13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
- Product Name
- 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
- CAS No.
- 363-23-5
- Chemical Name
- 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
- Synonyms
- PGEM;13,14-Dihydro-15-keto-PGE2;CUJMXIQZWPZMNQ-XYYGWQPLSA-N;15-keto-13,14-dihydroprostaglandine2;13,14-dihydro-15-oxo-prostaglandin E2;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2;13,14-Dihydro-15-ketoprostaglandinE2 solution;9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID;(5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid;(5Z,11α)-11-Hydroxy-9,15-dioxoprost-5-en-1-oic acid
- CBNumber
- CB8349316
- Molecular Formula
- C20H32O5
- Formula Weight
- 352.47
- MOL File
- 363-23-5.mol
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Property
- Boiling point:
- 538.1±45.0 °C(Predicted)
- Density
- 1.086±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 4.75±0.10(Predicted)
Safety
- Hazard Codes
- F,Xn,Xi
- Risk Statements
- 11-20/21/22-36/37/38-67-66-36
- Safety Statements
- 16-26-36
- RIDADR
- UN 1231 3/PG 2
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 14650
- Product name
- 13,14-dihydro-15-keto Prostaglandin E2
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $77
- Updated
- 2024/03/01
- Product number
- 14650
- Product name
- 13,14-dihydro-15-keto Prostaglandin E2
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $340
- Updated
- 2024/03/01
- Product number
- 14650
- Product name
- 13,14-dihydro-15-keto Prostaglandin E2
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $602
- Updated
- 2024/03/01
- Product number
- 10007214
- Product name
- 13,14-dihydro-15-keto Prostaglandin E2 MaxSpec? Standard
- Purity
- >95%
- Packaging
- 100μg
- Price
- $118
- Updated
- 2023/06/20
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Chemical Properties,Usage,Production
Description
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Δ13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 12 and 57 μM, respectively) or induce adenylate cyclase activity in the same cells (EC50s = >18 and >38 μM, respectively). Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery. Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC).
Uses
13,14-Dihydro-15-ketoPGE2 is a primary metabolite of PGE2 in plasma.
Definition
ChEBI: The 13,14-dihydro derivative of 15-oxo-prostaglandin E2.
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Preparation Products And Raw materials
Raw materials
Preparation Products
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Suppliers
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- Country
- Switzerland
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