Mog (35-55)

ChemicalBook > CAS DataBase List > Mog (35-55)

Product Name: Mog (35-55)
CAS No.: 149635-73-4
Chemical Name: Mog (35-55)
Synonyms: MOG (35-55);MEVGWYRSPFSRVVHLYRNGK;MK21;MOG (35-55) TFA;MOG (35-55), RAT;MOG (MOUSE, RAT);MOG (35-55), MOUSE, RAT;MOG (RAT, MOUSE, 35-55);MOG (35-55) (rat, Mouse);H-MEVGWYRSPFSRVVHLYRNGK-OH
CBNumber: CB8355199
Molecular Formula: C118H177N35O29S
Formula Weight: 2581.95
MOL File: 149635-73-4.mol

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Mog (35-55) Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: -15°C
solubility: ≥32.25 mg/mL in H2O; insoluble in EtOH; ≥86 mg/mL in DMSO
form: solid
Water Solubility: Soluble to 0.50 mg/ml in water
Sequence: H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-VAL-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH
InChI: InChI=1/C118H177N35O29S/c1-61(2)47-80(103(169)143-81(49-66-30-34-70(156)35-31-66)104(170)139-75(26-17-42-129-116(122)123)99(165)145-86(53-90(121)158)98(164)133-56-91(159)136-79(115(181)182)25-15-16-41-119)142-108(174)85(52-69-55-128-60-135-69)147-112(178)95(63(5)6)152-113(179)96(64(7)8)151-101(167)77(28-19-44-131-118(126)127)141-109(175)87(58-154)148-106(172)83(48-65-21-11-10-12-22-65)146-110(176)89-29-20-45-153(89)114(180)88(59-155)149-100(166)76(27-18-43-130-117(124)125)140-105(171)82(50-67-32-36-71(157)37-33-67)144-107(173)84(51-68-54-132-74-24-14-13-23-72(68)74)137-92(160)57-134-111(177)94(62(3)4)150-102(168)78(38-39-93(161)162)138-97(163)73(120)40-46-183-9/h10-14,21-24,30-37,54-55,60-64,73,75-89,94-96,132,154-157H,15-20,25-29,38-53,56-59,119-120H2,1-9H3,(H2,121,158)(H,128,135)(H,133,164)(H,134,177)(H,136,159)(H,137,160)(H,138,163)(H,139,170)(H,140,171)(H,141,175)(H,142,174)(H,143,169)(H,144,173)(H,145,165)(H,146,176)(H,147,178)(H,148,172)(H,149,166)(H,150,168)(H,151,167)(H,152,179)(H,161,162)(H,181,182)(H4,122,123,129)(H4,124,125,130)(H4,126,127,131)/t73-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,94-,95-,96-/s3
InChIKey: JMTCEFUSRHYJBF-LTFOILMJNA-N
SMILES: N1(CCC[C@H]1C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1C=CC(=CC=1)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O)CC(N)=O)C(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1C=CC(=CC=1)O)NC(=O)[C@@H](NC(CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(O)=O)NC([C@H](CCSC)N)=O)=O)CC1C2C=CC=CC=2NC=1 |&1:4,8,19,25,36,43,50,60,68,80,91,99,114,120,131,143,150,157,165,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2568
Product name: MOG(35-55)
Packaging: 1
Price: $229
Updated: 2021/12/16

ApexBio Technology

Product number: A8306
Product name: MOG(35-55)
Packaging: 5mg
Price: $294
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0003907
Product name: MOG (35-55)-MOUSE, RAT
Purity: 95.00%
Packaging: 1MG
Price: $733.72
Updated: 2021/12/16

ApexBio Technology

Product number: A8306
Product name: MOG(35-55)
Packaging: 1mg
Price: $98
Updated: 2021/12/16

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Mog (35-55) Chemical Properties,Usage,Production

Description

MOG (35-55) or myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. MOG (35-55) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. MOG (35-55) induces strong T and B cell responses and is highly encephalitogenic. MOG (35-55) induces T cell-mediated multiple sclerosis in animal models. When co-administered with ITE, MOG (35-55) induces tolerogenic dendritic cells and suppresses disease development in mouse preclinical models of multiple sclerosis.

Uses

Mog (35-55) can be used as an antigen immunized C57BL/6J mice to induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.

Biological Activity

mog (35-55) is a truncated peptide derived from the human myelin oligodendrocyte glycoprotein (mog). mog, a member of the immunoglobulin superfamily, is expressed wildly in the central nervous system. in mouse and rat models for human multiple sclerosis, mog is involved in inducing the experimental autoimmune encephalomyelitis. humoral auto-immunity to the myelin oligodendrocyte glycoprotein (mog) may be associated with the pathogenesis of multiple sclerosis (ms) [1].mog (35-55) is involved in inducing autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination [2]. in hla-dr2-transgenic mice, myelin oligodendrocyte glycoprotein-35-55 peptide induced severe chronic experimental autoimmune encephalomyelitis [3].mog35-55 was highly encephalitogenic and could induce strong t and b cell responses in rats [4]. in nod/lt mice (h-2g7) and c57bl/6 mice (h-2b), single injection of mog35-55 in cfa could induce ms-like disease [4].

storage

Store at -20°C

References

[1]. de march a k, de bouwerie m, kolopp-sarda m n, et al. anti-myelin oligodendrocyte glycoprotein b-cell responses in multiple sclerosis[j]. journal of neuroimmunology, 2003, 135(1): 117-125.
[2]. slavin a, ewing c, liu j, et al. induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein[j]. autoimmunity, 1998, 28(2): 109-120.
[3]. rich c, link j m, zamora a, et al. myelin oligodendrocyte glycoprotein‐35–55 peptide induces severe chronic experimental autoimmune encephalomyelitis in hla‐dr2‐transgenic mice[j]. european journal of immunology, 2004, 34(5): 1251-1261.
[4]. slavin a, ewing c, liu j, et al. induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein[j]. autoimmunity, 1998, 28(2): 109-120.

Mog (35-55) Preparation Products And Raw materials

Raw materials

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View Lastest Price from Mog (35-55) manufacturers

Dorne Chemical Technology co. LTD

Product: Mog (35-55) 149635-73-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2024-03-26

Shanghai Affida new material science and technology center

Product: Mog (35-55) 149635-73-4
Price: US $0.00-0.00/Box
Min. Order: 1Box
Purity: 99
Supply Ability: 50000KG/month
Release date: 2024-04-11

Zibo Hangyu Biotechnology Development Co., Ltd

Product: ACTH (1-14) 149635-73-4
Price: US $0.10-0.30/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-01-03

149635-73-4, Mog (35-55)Related Search:

H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH PLP (139-151) Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (TFA) BIOT-MEVGWYRSPFSRVVHLYRNGK-OH Mog (35-55)

H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH

H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH (MOUSE, RAT)

MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS

MEVGWYRSPFSRVVHLYRNGK

MK21

H-MEVGWYRSPFSRVVHLYRNGK-OH

MET-GLU-VAL-GLY-TRP-TYR-ARG-PRO-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS

MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS: MEVGWYRSPFSRVVHLYRNGK

MOG (35-55) (rat, Mouse)

MYELIN OLIGODENDROCYTE GLYCOPRTOTEIN PEPTIDE FRAGMENT (33-55) RAT, MOUSE, MOG Peptide (33-55) Rat, Mouse

Myelin Oligodendrocyte Glycoprotien (35-55) rat MOG (35-55)

Myelin Oligodendrocyte Glycoprotein (35-55)

MOG(35-55)| Myelin Oligodendrocyte Glycoprotein Peptide: 35-55,rat,mouse

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat

MYELIN OLIGODENDROCYTE GLYCOPROTEIN PEPTIDE (35-55) (RAT, MOUSE)

MYELIN OLIGODENDROCYTE GLYCOPROTEIN PEPTIDE FRAGMENT 35-55 RAT, MOUSE

MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55) (MOUSE, RAT)

MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55), RAT

MYELIN OLIGODENDROCYTE PROTEIN (35-55)

MOG (35-55), MOUSE, RAT

MOG (35-55), RAT

MOG (35-55)

MOG (MOUSE, RAT)

MOG PEPTIDE (35-55) (RAT, MOUSE)

MOG (RAT, MOUSE, 35-55)

L-Lysine, L-methionyl-L-α-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-seryl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl-

H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH USP/EP/BP

MOG (35-55) TFA

L-Lysine,L-methionyl-L-a-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-seryl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl-

149635-73-4

C118H177N35O29S

peptide

Various Peptides