ChemicalBook > CAS DataBase List > Anticholinesterase

Anticholinesterase

Product Name
Anticholinesterase
CAS No.
9000-81-1
Chemical Name
Anticholinesterase
Synonyms
ACHE;ACETYLCHOLINESTERASE;Native Electrophorus electricus (electric eel) Acetylcholinesterase;AcCholE;EC 3.1.1.7;Cholinesterase I;ANTICHOLINESTERASE;TRUE CHOLINESTERASE;Acetylcholinesterases;ACETYLCHOLINE ESTERASE
CBNumber
CB8359935
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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Anticholinesterase Property

storage temp. 
-20°C
solubility 
H2O: 1 mg/mL
form 
powder
color 
slightly yellow
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Safety

Hazard Codes 
B
WGK Germany 
3
F 
10-21
Toxicity
The inhibition of AChE by these anticholinesterases leads to an accumulation of endogenous ACh, and thus results in hyperactivation of cholinergic receptors. Signs of acute poisoning can include irritability, tremors, convulsions, and predominately parasympathetic effects, with death usually the result of respiratory failure. Since AChE is contained in erythrocytes, the assay of erythrocyte AChE activity can be used as a diagnostic tool to assess exposure to organophosphorus anticholinesterases.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C3389
Product name
Acetylcholinesterase from Electrophorus electricus (electric eel)
Purity
Type VI-S, lyophilized powder, 200-1,000?units/mg protein
Packaging
500units
Price
$95
Updated
2024/03/01
Sigma-Aldrich
Product number
C3389
Product name
Acetylcholinesterase from Electrophorus electricus (electric eel)
Purity
Type VI-S, lyophilized powder, 200-1,000?units/mg protein
Packaging
2000units
Price
$252
Updated
2024/03/01
Sigma-Aldrich
Product number
C3389
Product name
Acetylcholinesterase from Electrophorus electricus (electric eel)
Purity
Type VI-S, lyophilized powder, 200-1,000?units/mg protein
Packaging
10000units
Price
$862
Updated
2024/03/01
Sigma-Aldrich
Product number
C2888
Product name
Acetylcholinesterase from Electrophorus electricus (electric eel)
Purity
Type V-S, lyophilized powder, ≥1,000?units/mg protein
Packaging
500units
Price
$133
Updated
2024/03/01
Sigma-Aldrich
Product number
C2888
Product name
Acetylcholinesterase from Electrophorus electricus (electric eel)
Purity
Type V-S, lyophilized powder, ≥1,000?units/mg protein
Packaging
1000units
Price
$268
Updated
2024/03/01
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Anticholinesterase Chemical Properties,Usage,Production

Uses

Pesticides.

Uses

Acetylcholinesterase (AChE) from Sigma has been used in the structure-activity study of phosphoramido acid esters as inhibitors of AChE.

Uses

Acetylcholinesterase from Electrophorus electricus (electric eel) has been used:

  • in acetylcholinesterase activity assay
  • to study its effects on Xenopus embryonic hippocampal cells
  • to study the effect of acetylcholine inhibitors on development and plasticity

Definition

Any substance that inhibits or inactivates acetylcholinesterase, thereby preventing the hydrolysis of acetylcholine. Their action leads to an accumulation of endogenous acetylcholine with a resultant hyperactivity of cholinergic neurons, which can prove lethal.

General Description

Predominantly exists as a tetrameric glycoprotein composed of disulfide-linked homodimers with a monomer MW of ~80 kDa.

Hazard

Tremors; convulsions; respiratory failure; death.

Biochem/physiol Actions

Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.

Anticholinesterase Preparation Products And Raw materials

Raw materials

Preparation Products

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Anticholinesterase Suppliers

China 132 Europe 2 Germany 2 Switzerland 1 United States 6 Global 143
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View Lastest Price from Anticholinesterase manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Anticholinesterase 9000-81-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-24
Career Henan Chemical Co
Product
Anticholinesterase 9000-81-1
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-24

9000-81-1, AnticholinesteraseRelated Search:

Acephate N-ACETYLGUANIDINE TRIS(ACETYLACETONATO)YTTRIUM N-HYDRATE Acetosyringone Acetyl coenzyme A sodium salt 2,5-Dimethoxyacetoacetanilide ACETYL COENZYME A (C2:0) LITHIUM Acetylsalicylic acid CARNITINE ACETYLTRANSFERASE 2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide Cupric acetylacetonate Ferric acetylacetonate COBALT(II) ACETYLACETONATE N-BUTYLISOCYANIDE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tris(2,4-pentanedionato)chroMiuM(III) Butyrylcholinesterase

  • Esterase, acetyl choline
  • TRUE CHOLINESTERASE
  • TRUE CHOLINESTERASE HUMAN
  • TRUE CHOLINESTERASE TYPE VI-S
  • TRUE CHOLINESTERASE TYPE V-S
  • TRUE CHOLINESTERASE TYPE XII-S
  • ACETYLCHOLINESTERASE TYPE III ELECTRIC
  • ACETYLCHOLINE ESTERASE F. ELECTROPHORUS ELECT., ~850 U/MG
  • CHOLINESTERASE, ACETYL AMPHIPHILIC FROM HUMAN ERYTH
  • CHOLINESTERASE ACETYL TYPE XIIIFROM HUMA N ERYTHROC
  • ACETYLCHOLINE ESTERASE MEMBR.B. F. BOV. ERYTHROC. ~400U/MG*
  • Acetylcholinesterase from electric eel
  • ACETYLCHOLINE ESTERASE
  • ACETYLCHOLINESTERASE
  • ACETYLCHOLINE ACETYLHYDROLASE
  • ACETYLCHOLINE ACETYLHYDROLASE HUMAN
  • ACETYLCHOLINE ACETYLHYDROLASE TYPE VI-S
  • ACETYLCHOLINE ACETYLHYDROLASE TYPE V-S
  • ACETYLCHOLINE ACETYLHYDROLASE TYPE XII-S
  • EC 3.1.1.7
  • CHOLINESTERASE, ACETYL
  • CHOLINESTERASE, ACETYL HUMAN
  • CHOLINESTERASE, ACETYL TYPE VI-S
  • CHOLINESTERASE, ACETYL TYPE V-S
  • CHOLINESTERASE, ACETYL TYPE XII-S
  • ANTICHOLINESTERASE
  • Acetylcholinesterase from electric eel, 200u/g
  • Acetylcholinesterase, 200u/g
  • CHOLINESTERASE, ACETYL TYPE VI-S FROMELE CTRIC EEL
  • ACETYLCHOLINESTERASE TYPE XII-S BOVINE
  • CHOLINESTERASE, ACETYL TYPE V-SFROM ELEC TRIC EEL
  • CHOLINESTERASE, ACETYL HUMANRECOMBINANT
  • ACETYLCHOLINE ESTERASE F. ELECTROPHORUS&
  • AcetylcholinesteraseExBovineErythro-
  • Cholinesterase,BeefPancreas
  • Acetylcholinesterasefrombovineerythrocytes
  • acetylcholinesterase from electrophorus electricus (electric eel)
  • acetylcholinesterase from human erythrocytes
  • acetylcholinesterase human
  • ACETYL CHOLINESTERASE TYPE V-S FROM ELECTRIC EEL
  • Acetylcholine acetylhydrolase, AChE, Cholinesterase, Acetyl
  • Acetylcholine acetylhydrolase, AChE
  • Acetylcholinesterase-Agarose
  • Acetylcholine acetylhydrolase, AChE, Acetylcholine Esterase, membrane-bound, from bovine erythrocytes
  • Acetylcholinesterase human,AChE, Acetylcholine acetylhydrolase
  • Acetylcholinesterase from human erythrocytes,AChE, Acetylcholine acetylhydrolase
  • CHOLINESTERASE ACETYL TYPE III
  • Acetylcholinesterase from Electrophorus electricus (electric eel),AChE, Acetylcholine acetylhydrolase, Cholinesterase, Acetyl
  • ACHE
  • Acetylcholine esterase from bovine erythrocytes, lyophil.
  • Esterase, acetylcholine (ELECTRIC EEL)
  • ACETYLCHOLINESTERASE FROM ELECTRO
  • Cholinesterase I
  • Acetylthiocholinesterase
  • Acetylcholinesterases
  • Acetylcholinesterase (AChE)
  • Acetylcholine hydrolase
  • Acetyl beta-methylcholinesterase