ChemicalBook > CAS DataBase List > Anticholinesterase
Anticholinesterase
- Product Name
- Anticholinesterase
- CAS No.
- 9000-81-1
- Chemical Name
- Anticholinesterase
- Synonyms
- ACHE;ACETYLCHOLINESTERASE;Native Electrophorus electricus (electric eel) Acetylcholinesterase;AcCholE;EC 3.1.1.7;Cholinesterase I;ANTICHOLINESTERASE;TRUE CHOLINESTERASE;Acetylcholinesterases;ACETYLCHOLINE ESTERASE
- CBNumber
- CB8359935
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
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Anticholinesterase Property
- storage temp.
- -20°C
- solubility
- H2O: 1 mg/mL
- form
- powder
- color
- slightly yellow
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Safety
- Hazard Codes
- B
- WGK Germany
- 3
- F
- 10-21
- Toxicity
- The inhibition of AChE by these anticholinesterases leads to an accumulation of endogenous ACh, and thus results in hyperactivation of cholinergic receptors. Signs of acute poisoning can include irritability, tremors, convulsions, and predominately parasympathetic effects, with death usually the result of respiratory failure. Since AChE is contained in erythrocytes, the assay of erythrocyte AChE activity can be used as a diagnostic tool to assess exposure to organophosphorus anticholinesterases.
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P285In case of inadequate ventilation wear respiratory protection.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C3389
- Product name
- Acetylcholinesterase from Electrophorus electricus (electric eel)
- Purity
- Type VI-S, lyophilized powder, 200-1,000?units/mg protein
- Packaging
- 500units
- Price
- $95
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C3389
- Product name
- Acetylcholinesterase from Electrophorus electricus (electric eel)
- Purity
- Type VI-S, lyophilized powder, 200-1,000?units/mg protein
- Packaging
- 2000units
- Price
- $252
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C3389
- Product name
- Acetylcholinesterase from Electrophorus electricus (electric eel)
- Purity
- Type VI-S, lyophilized powder, 200-1,000?units/mg protein
- Packaging
- 10000units
- Price
- $862
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C2888
- Product name
- Acetylcholinesterase from Electrophorus electricus (electric eel)
- Purity
- Type V-S, lyophilized powder, ≥1,000?units/mg protein
- Packaging
- 500units
- Price
- $133
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C2888
- Product name
- Acetylcholinesterase from Electrophorus electricus (electric eel)
- Purity
- Type V-S, lyophilized powder, ≥1,000?units/mg protein
- Packaging
- 1000units
- Price
- $268
- Updated
- 2024/03/01
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Anticholinesterase Chemical Properties,Usage,Production
Uses
Pesticides.
Uses
Acetylcholinesterase (AChE) from Sigma has been used in the structure-activity study of phosphoramido acid esters as inhibitors of AChE.
Uses
Acetylcholinesterase from Electrophorus electricus (electric eel) has been used:
- in acetylcholinesterase activity assay
- to study its effects on Xenopus embryonic hippocampal cells
- to study the effect of acetylcholine inhibitors on development and plasticity
Definition
Any substance that inhibits or inactivates acetylcholinesterase, thereby preventing the hydrolysis of acetylcholine. Their action leads to an accumulation of endogenous acetylcholine with a resultant hyperactivity of cholinergic neurons, which can prove lethal.
General Description
Predominantly exists as a tetrameric glycoprotein composed of disulfide-linked homodimers with a monomer MW of ~80 kDa.
Hazard
Tremors; convulsions; respiratory failure; death.
Biochem/physiol Actions
Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.
Anticholinesterase Preparation Products And Raw materials
Raw materials
Preparation Products
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Anticholinesterase Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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View Lastest Price from Anticholinesterase manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Anticholinesterase 9000-81-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98.0%
- Supply Ability
- 1kg/month
- Release date
- 2021-08-24
Career Henan Chemical Co
- Product
- Anticholinesterase 9000-81-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
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