ChemicalBook > CAS DataBase List > 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE

2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE

Product Name
2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE
CAS No.
10592-27-5
Chemical Name
2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE
Synonyms
2,3-Dihydro-7-azaindole;7-azaindoline;2,3-Dihydro-7-azaindole 98%;1H,2H,3H-pyrrolo[2,3-b]pyridine;2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro-;2,3-Dihydropyrrolo[2,3-b]pyridine, 97+%;1H-Pyrrolo[2,3-b]pyridine,2,3-dihydro-(6CI,8CI,9CI);2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine 7-azaindoline;2,3 DIHYDRO 1H PYRROLO[2,3 B]PYRIDINE,2,3DIHYDRO1HPYRROLO[2,3B]PYRIDINE
CBNumber
CB8366902
Molecular Formula
C7H8N2
Formula Weight
120.15
MOL File
10592-27-5.mol
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2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE Property

Melting point:
78-83 °C
Boiling point:
114°C/10mmHg(lit.)
Density 
1.23
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
10.75±0.20(Predicted)
form 
Powder
color 
White
Water Solubility 
Slightly soluble in water.
λmax
306nm(Cyclohexane)(lit.)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
702358
Product name
2,3-Dihydro-7-azaindole
Purity
97%
Packaging
1g
Price
$104
Updated
2023/06/20
Sigma-Aldrich
Product number
702358
Product name
2,3-Dihydro-7-azaindole
Purity
97%
Packaging
5g
Price
$147
Updated
2023/01/07
TCI Chemical
Product number
D5078
Product name
2,3-Dihydro-7-azaindole
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$19
Updated
2025/07/31
TCI Chemical
Product number
D5078
Product name
2,3-Dihydro-7-azaindole
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$54
Updated
2025/07/31
TRC
Product number
D451585
Product name
2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine
Packaging
250mg
Price
$55
Updated
2021/12/16
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2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Beige powder

Uses

It can be used as pharmaceutical raw material and intermediate.

Synthesis

271-63-6

10592-27-5

a) 7-azaindole (100 g, 0.846 mol), Ni/Al?O? catalyst (12 g, 10 wt%), and toluene (200 g) were added to the autoclave and stirred and mixed homogeneously to obtain the reaction solution A; b) the autoclave was replaced with nitrogen for 8 times, followed by hydrogen for 4 times to ensure that the reaction system was oxygen-free; c) the reaction solution A was subjected to hydrogenation reaction at a pressure of 2 MPa hydrogen and 130 °C; d) after the completion of the reaction, the hydrogenation mixture was filtered to remove the catalyst to obtain the filtrate B; e) after distillation and recovery of the organic solvent from the filtrate B, 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine (94.59 g, 93.4% yield) was obtained, and the purity of the product was analyzed by gas chromatography, which was ≥98%.

References

[1] Patent: CN107987076, 2018, A. Location in patent: Paragraph 0043-0047; 0058-0063; 0075-0079
[2] Patent: CN106188050, 2016, A. Location in patent: Paragraph 0016
[3] Patent: US2011/144105, 2011, A1. Location in patent: Page/Page column 16
[4] Synthesis, 2005, # 15, p. 2503 - 2506
[5] Patent: WO2004/78757, 2004, A2. Location in patent: Page 32; 48-49

2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE Suppliers

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View Lastest Price from 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 10592-27-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 10592-27-5
Price
US $500.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-04

10592-27-5, 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINERelated Search:

5-BROMO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine 2-chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine 4-Methoxy-1-methyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid 4-chloro-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-1,3-DIONE 6,7-dihydro-5H-pyrrolo[3,4-b] pyridine dihydrochloride,6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE 1,3-dihydro-2H-pyrrolo[2,3-c]pyridine-2-one 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE HYDROCHLORIDE 1,3-DIHYDRO-2H-PYRROLO[2,3-B]PYRIDINE-2-ONE 7-Azaindole 5-METHOXY-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID 5-METHYL-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBONITRILE PGP-4008

  • 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE
  • 2,3-Dihydro-7-azaindole 98%
  • 7-azaindoline
  • 1H-Pyrrolo[2,3-b]pyridine,2,3-dihydro-(6CI,8CI,9CI)
  • 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine 7-azaindoline
  • 2,3-Dihydro-7-azaindole
  • 1H,2H,3H-pyrrolo[2,3-b]pyridine
  • 2,3-Dihydropyrrolo[2,3-b]pyridine, 97+%
  • 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro-
  • 2,3 DIHYDRO 1H PYRROLO[2,3 B]PYRIDINE,2,3DIHYDRO1HPYRROLO[2,3B]PYRIDINE
  • 10592-27-5
  • PYRROLIDINE
  • API intermediates