ChemicalBook > CAS DataBase List > 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

Product Name
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
CAS No.
124750-51-2
Chemical Name
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
Synonyms
Losaint-B;ALSTint-A04;Valsartan IMP;Valsartan Impurity;Valsartan Impurity 8;Valsartan Impurity 9;TRITYLATED BROMO IMP;Fimasartan Impurity B;Valsartan impurity 19;Valsartan intermediate
CBNumber
CB8369024
Molecular Formula
C33H25BrN4
Formula Weight
557.48
MOL File
124750-51-2.mol
More
Less

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Property

Melting point:
152-155°C
Boiling point:
61°C/12mmHg(lit.)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Chloroform and Methanol (Sparingly)
form 
Solid
pka
0.29±0.10(Predicted)
color 
White
Stability:
Moisture Sensitive
InChI
InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2
InChIKey
ZTFVTXDWDFIQEU-UHFFFAOYSA-N
SMILES
N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1
CAS DataBase Reference
124750-51-2(CAS DataBase Reference)
More
Less

Safety

RIDADR 
UN 2811 6.1/PG III
HazardClass 
6.1
PackingGroup 
III
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T137073
Product name
5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE
Purity
Aldrich
Packaging
10mg
Price
$139
Updated
2024/03/01
Biosynth Carbosynth
Product number
FB19245
Product name
5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole
Packaging
50g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19245
Product name
5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole
Packaging
100g
Price
$240
Updated
2021/12/16
AK Scientific
Product number
J11478
Product name
OlmesartanImpurity20
Packaging
100mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19245
Product name
5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole
Packaging
25g
Price
$100
Updated
2021/12/16
More
Less

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Chemical Properties,Usage,Production

Description

5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole is an intermediate in the synthesis of Losartan and Valsartan. Utilized for various purposes, 5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole has found application as a fluorescent probe to identify DNA damage. It serves as a photosensitizer in photodynamic therapy and acts as a catalyst in polymer synthesis. Furthermore, this compound functions as a fluorescent label to detect proteins and as a fluorescent indicator to detect metal ions.

Chemical Properties

Off-White Solid

Uses

Used as Olmesartan medoxomil related intermediate, Olmesartan medoxomil is an angiotensin II receptor antagonist[1]. 

Application

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts.

Hazard

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes.

References

[1] HAI Z. Determination of the related substances in N-triphenylmethyl-5-(4’-bromomethylbiphenyl-2-yl-) terazole by HPLC[J]. West China Journal of Pharmaceutical Sciences, 2015.

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Suppliers

Canada 2 China 404 Europe 2 France 1 Germany 3 India 95 Japan 1 Slovakia 1 South Korea 2 Ukraine 1 United Kingdom 6 United States 27 Global 545
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
KKyemistry (India) Pvt. Ltd.
Tel
--
Fax
--
Email
info@kyemistryindia.com
Country
India
ProdList
197
Advantage
50
Saptagir Laboratories PVT.LTD.
Tel
--
Fax
--
Email
info@saptagirlabs.com
Country
India
ProdList
12
Advantage
58
SGMR Pharmaceuiticals Pvt Ltd
Tel
--
Fax
--
Email
api.marketing@sgmrpharma.com
Country
India
ProdList
51
Advantage
58
Dhanvi Exim Services
Tel
--
Fax
--
Email
info@dhanviexim.com
Country
India
ProdList
204
Advantage
58
Sris Pharmaceuticals
Tel
--
Fax
--
Email
marketing@srispharma.co.in
Country
India
ProdList
130
Advantage
58
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Chemspec Chemicals Pvt., Ltd.
Tel
--
Fax
--
Email
ccpl@chemspec.co.in
Country
India
ProdList
11
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
SVS Interchem (SVS)
Tel
--
Fax
--
Email
svsinterchem@gmail.com
Country
India
ProdList
117
Advantage
58
Chaturya Biotech (Tanuj Life Sciences)
Tel
--
Fax
--
Email
info@chaturyabiotech.com
Country
India
ProdList
398
Advantage
58
Angels Pharma India Private Limited.
Tel
--
Fax
--
Email
info@angelspharma.com
Country
India
ProdList
6
Advantage
58
New Rise Life Science
Tel
--
Fax
--
Email
info@newriselifescience.com
Country
India
ProdList
150
Advantage
58
Synthink Research Chemicals
Tel
--
Fax
--
Country
India
ProdList
398
Advantage
58
S. Amit Speciality Chemicals Pvt. Ltd.
Tel
--
Fax
--
Email
gupta@s-amit.com
Country
India
ProdList
177
Advantage
58
OctaneX Labs
Tel
--
Fax
--
Email
info@octanexlabs.com
Country
India
ProdList
101
Advantage
58
Corvine Chemicals & Pharmaceuticals Ltd.
Tel
--
Fax
--
Email
info@corvinechemicals.com
Country
India
ProdList
10
Advantage
58
Unitrade Agencies
Tel
--
Fax
--
Country
India
ProdList
197
Advantage
58
Trignokem International.
Tel
--
Fax
--
Email
ignokem@gmail.com
Country
India
ProdList
233
Advantage
58
Sibram Pharmaceutical
Tel
--
Fax
--
Email
contact@sibram.com
Country
India
ProdList
136
Advantage
58
Saburi Life Sciences
Tel
--
Fax
--
Email
info@saburilifesciences.com
Country
India
ProdList
47
Advantage
58
Clearsynth Labs
Tel
--
Fax
--
Email
fo@clearsynth.com
Country
India
ProdList
3887
Advantage
58
Veronicaa Pharmachem
Tel
--
Fax
--
Country
India
ProdList
23
Advantage
58
Carbontree (T)
Tel
--
Fax
--
Email
info@carbontree.in
Country
India
ProdList
56
Advantage
58
Vasista Pharma Chem Pvt., Ltd. (Vasista Group)
Tel
--
Fax
--
Email
srinivasaraju@vasista.co.in
Country
India
ProdList
34
Advantage
58
Pharma Direct International
Tel
--
Fax
--
Email
pharmadirectintl@gmail.com
Country
India
ProdList
44
Advantage
58
Anlon Healthcare Pvt., Ltd.
Tel
--
Fax
--
Email
somesh@anloncro.com
Country
India
ProdList
18
Advantage
58
Global Chemie
Tel
--
Fax
--
Country
India
ProdList
162
Advantage
58
Bizten Impex Private Limited.
Tel
--
Fax
--
Country
India
ProdList
109
Advantage
58
Chemic Life Sciences Pvt., Ltd.
Tel
--
Fax
--
Email
chemiclifesciences@gmail.com
Country
India
ProdList
7
Advantage
58
Vindhya Pharma India Pvt., Ltd.
Tel
--
Fax
--
Email
dn@vindhyapharma.com
Country
India
ProdList
51
Advantage
58
Ralington Pharma.
Tel
--
Fax
--
Email
info@ralingtonpharma.com
Country
India
ProdList
311
Advantage
58
Maithili Life Sciences Pvt., Ltd. (MLSP)
Tel
--
Fax
--
Email
info@maithililifesciences.com
Country
India
ProdList
9
Advantage
58
Arunodaya Pharma Pvt., Ltd.
Tel
--
Fax
--
Email
arunodayapharma@gmail.com
Country
India
ProdList
62
Advantage
58
Anant Pharmaceuticals Pvt. ltd
Tel
--
Fax
--
Email
info@anantlabs.com
Country
India
ProdList
736
Advantage
58
Psn Medicare Private Limited
Tel
--
Fax
--
Country
India
ProdList
50
Advantage
58
Fine Chemicals & Scientific Co.
Tel
--
Fax
--
Email
finechemicals@gmail.com
Country
India
ProdList
67
Advantage
58
Chempro Pharma Pvt. Ltd.
Tel
--
Fax
--
Email
ankitsehgal@chemprogroup.net
Country
India
ProdList
170
Advantage
58
Nivon Specialties (India)
Tel
--
Fax
--
Email
info@nivonindia.com
Country
India
ProdList
154
Advantage
58
Oceanic Pharmachem Pvt. Ltd.
Tel
--
Fax
--
Email
info@oceanicpharmachem.com
Country
India
ProdList
2005
Advantage
58
Satyan Pharmaceuticals Pvt Ltd.
Tel
--
Fax
--
Email
common@satyanltd.com
Country
India
ProdList
54
Advantage
58
Kkyemistry (india) Pvt., Ltd.
Tel
--
Fax
--
Email
marketing@kyemistryindia.com
Country
India
ProdList
163
Advantage
58
Global Pharma Tek (GPT)
Tel
--
Fax
--
Email
ramaiah.t@globalpharmatek.com
Country
India
ProdList
28
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Telangana Pharmatech
Tel
--
Fax
--
Country
India
ProdList
34
Advantage
58
ChemOrbit International
Tel
--
Fax
--
Email
2014@gmail.com
Country
India
ProdList
264
Advantage
58
Manus Aktteva Biopharma LLP
Tel
--
Fax
--
Country
India
ProdList
655
Advantage
58
Blue Waters International
Tel
--
Fax
--
Email
dharmesh.gandhi@blue-waters.in
Country
India
ProdList
86
Advantage
58
Smilax Laboratories Limited
Tel
--
Fax
--
Country
India
ProdList
37
Advantage
58
Molecraft LifeSciences Pvt Ltd
Tel
--
Fax
--
Email
info@molecraft.com
Country
India
ProdList
757
Advantage
0
More
Less

View Lastest Price from 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole manufacturers

Sinoway Industrial co., ltd.
Product
BBTT 124750-51-2
Price
US $0.00/KG
Min. Order
2KG
Purity
99% up, High Density
Supply Ability
20 tons
Release date
2021-09-09
Hebei Dangtong Import and export Co LTD
Product
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 124750-51-2
Price
US $36.00-27.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg
Release date
2023-09-19
.GZ HONESTCHEM CO.,LTD
Product
N-(Triphenylmethyl)-5-(4-Bromomethylbiphenyl-2-yl-)Tetrazole 124750-51-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
500KG
Release date
2021-07-02

124750-51-2, 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazoleRelated Search:

4,4'-Dimethylbiphenyl Decabromodiphenyl oxide FIREMASTER BP-6 Biphenyl 2-Bromobiphenyl 2,3,5-Triphenyltetrazolium chloride 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide Fimasartan 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide 2-(2-butyl-4-hydroxy-6-MethylpyriMidin-5-yl)-N,N-diMethylacetaMide OlMesartan MedoxoMil iMpurity V N-Trityl Olmesartan Ethyl Ester METHYL TRIPHENYLMETHYL ETHER 2-(2-butyl-4-Methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-1,6-dihydropyriMidin-5-yl)-N,N-diMethylethanethioaMide 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester Diethyl 2-propylImidazoledicarbonate OlMesartan MedoxoMil Butyl IMpurity 4,5-Dimethyl-1,3-dioxol-2-one

  • N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole
  • N-(TRIPHENYLMETHYL)-5-(4'-BROMOMETHYLBIPHENYL-2-YL) TETRAZOLE
  • 5-(4'-BROMOMETHYL-1,1'-BIPHENYL-2-YL)-1-TRIPHENYLMETHYL-1H-TETRAZOLE
  • 5-(4'-BROMOMETHYL-BIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE
  • 1H-Tetrazole, 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-
  • Trityl tetrazole bromomethyl biphenyl
  • 5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-
  • 5-[4'-(Bromomethyl)[1,1'-Biphenyl]-1-(Triphenylmethyl)Tetrazole]
  • 2-(N-Triphenylmethyltetrazolyl)-4-Bromomethylbiphenyl)97%
  • Valsartan intermediate
  • 5-[4Bromomethyl-(1,1biphenyl)-2-yl]-1-triphenylmethyltetrazole
  • N-(TRIPHENYLMETHYL)-5-(4''-BROMOMETHYLBIPHENYL-2-YL-)TETRAZOLE(BBTT)
  • 5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-trityl-1H-tetrazole
  • (TRIPHENYLMETHYL)TETRAZOLE
  • Fimasartan Impurity B
  • Olmesartan Medoxomil Impurity 32
  • Olmesartan Medoxomil Impurity 30
  • N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole
  • intermediate of sartan drugs
  • Olmesartan Medoxomil-21
  • 5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE
  • N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yi-)tetrazole
  • N-(Triphenylmethyl)C5-(4'-Bromomethylbiphenyl-2Yl)Tetrazole
  • n-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole,N-(Triphenyl methyl)-5-(4'-Bromomethyl-biphenyl-2-yl)tetrazole(TTBB,BBTT)
  • 5-(4'-BroMoMethyl-1,1'-biphenyl-2-yl)-1-triphenylM
  • 5-[5-(broMoMethyl)-2-phenylphenyl]-1-(triphenylMethyl)-1H-1,2,3,4-tetrazole
  • Candesartan BroMo IMpurity：5-(4'-(BroMoMethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetrazole
  • [2'-(1-Trityl-1H-tetrazol-5-yl)biphenyl-4-yl]Methyl BroMide
  • 4-[2'-(N-TriphenylMethyltetrazol-5-yl)phenyl]benzyl BroMide
  • 4'-BroMoMethyl-2-(1-trityl-1H-tetrazol-5-yl)biphenyl
  • 4-BroMoMethyl-2'-[N-triphenylMethyl-1H-tetrazol-5-yl]biphenyl
  • N-(Trityl)-5-(4'-BroMoMethyl Biphenyl-2-Yl)-Tetrazole
  • Irbesartan BroMo IMpurity
  • Olmesartan Impurity (N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yl)tetrazole)
  • 5-{2-[4-(bromomethyl)phenyl]phenyl}-1-(triphenylmethyl)-1H-1,2,3,4-tetrazole
  • ALSTint-A04
  • Losaint-B
  • Olmesartan1 Impurity 28
  • N-(Triphenylmethyl)-5-(4’-bromomethylbiphenylyl)tetrazole
  • Losartan BroMo N1 Trityl IMpurity
  • Valsartan BroMo IMpurity
  • Irbesartan BroMo N1-Trityl IMpurity
  • 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole
  • OlMesartan IMpurity (N-(TriphenylMethyl)-5-(4'-broMoMethylbiphenylyl)tetrazole)
  • 5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetrazole 200mg Desbutoxy Valsartan Benzyl Ester
  • Candesartan Bromo N1-Trityl Impurity
  • Valsartan Impurity
  • N-(Tm)-5-(4'-bromomethylbiphenyl-2-yl ) tetrazole(TTBB)
  • Valsartan Impurity 8
  • Valsartan Impurity 9
  • Valsartan impurity 19
  • (R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)propionamido)-3-methylbutanoic acid
  • Valsartan IMP
  • 5-[4'-(Bromomethyl)-1,1'-biphenyl-2-yl]-1-triphenylmethyl-1H-tetrazole&gt
  • Irbesartan Bromo N2-Trityl Impurity
  • 5-(4'-Bromomethyl-1,1'- biphenyl-2-yl)-1- triphenylmethyl-1Htetrazole （BBTT）
  • 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole USP/EP/BP
  • 1-Triphenylmethyl-5-[4'-(bromomethyl)biphenyl-2-yl]tetrazole DISCONTINUED, offer B685310