2,3,5-Triphenyltetrazolium chloride
- Product Name
- 2,3,5-Triphenyltetrazolium chloride
- CAS No.
- 298-96-4
- Chemical Name
- 2,3,5-Triphenyltetrazolium chloride
- Synonyms
- TTC;tt;RT;TTZ;TETRAZOLIUM SALT;TTL;red tetazolium;TETRAZOLIUM CHLORIDE;TRIPHENYLTETRAZOLIUM CHLORIDE;2,3,5-TRIPHENYL-2H-TETRAZOLIUM CHLORIDE
- CBNumber
- CB9666209
- Molecular Formula
- C19H15ClN4
- Formula Weight
- 334.8
- MOL File
- 298-96-4.mol
2,3,5-Triphenyltetrazolium chloride Property
- Melting point:
- 250 °C(lit.)
- Boiling point:
- 490.96°C (rough estimate)
- Density
- 1.1704 (rough estimate)
- bulk density
- 230kg/m3
- refractive index
- 1.6110 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: may be clear to slightly hazy
- form
- powder
- color
- faint yellow
- PH
- 3.7 (20°C, 10g/L in H2O)
- Water Solubility
- Soluble in water, ethanol and acetone. Insoluble in ether.
- λmax
- 247 nm
- Sensitive
- Light Sensitive & Hygroscopic
- Merck
- 14,9744
- BRN
- 3923356
- Stability:
- Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents.
- Biological Applications
- Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer
- InChIKey
- PKDBCJSWQUOKDO-UHFFFAOYSA-M
- CAS DataBase Reference
- 298-96-4(CAS DataBase Reference)
- EPA Substance Registry System
- 2,3,5-Triphenyltetrazolium chloride (298-96-4)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- XF8100000
- F
- 3-8-10
- TSCA
- Yes
- HS Code
- 29339900
- Toxicity
- LD50 intravenous in mouse: 5600ug/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T8877
- Product name
- 2,3,5-Triphenyltetrazolium chloride
- Purity
- ≥98.0% (HPLC)
- Packaging
- 5g
- Price
- $62.9
- Updated
- 2025/07/31
- Product number
- 1.08380
- Product name
- 2,3,5-Triphenyltetrazolium chloride
- Purity
- for microbiology
- Packaging
- 10g
- Price
- $67.1
- Updated
- 2025/07/31
- Product number
- 17779
- Product name
- 2,3,5-Triphenyl-tetrazolium chloride solution
- Purity
- suitable for microbiology
- Packaging
- 10amp
- Price
- $281
- Updated
- 2025/07/31
- Product number
- 1.08380
- Product name
- 2,3,5-Triphenyltetrazolium chloride
- Purity
- for microbiology
- Packaging
- 100g
- Price
- $642
- Updated
- 2025/07/31
- Product number
- TX1510
- Product name
- 2,3,5-Triphenyl-2H-Tetrazolium Chloride
- Packaging
- 25g
- Price
- $281
- Updated
- 2022/05/15
2,3,5-Triphenyltetrazolium chloride Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies.
Uses
2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia
Uses
In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases.
Definition
ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion.
General Description
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.
Synthesis
531-52-2
298-96-4
E. The 2,3,5-triphenylformamidine (IV-1) solid obtained in Step D was mixed with 300 mL of dichloromethane and 300 mL of water. After the solid was completely dissolved, N-chlorosuccinimide (0.11 mol, 14.7 g) was added and the reaction was carried out with stirring at 0 °C for 5 h. F. The reaction mixture from Step E was allowed to partition and the upper aqueous phase was separated. The organic phase was distilled under reduced pressure to remove the solvent to give the crude product 2,3,5-triphenyltetrazole (V-1). The crude product was purified by recrystallization with chloroform to give 30.2 g of pure product (yield: 90%).
Purification Methods
Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.]
References
[1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983, vol. 22, # 8, p. 771 - 775
[2] J. Appl. Chem. USSR (Engl. Transl.), 1983, vol. 56, # 3, p. 617 - 621
[3] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1983, vol. 56, # 3, p. 649 - 653
[4] Patent: CN108440433, 2018, A. Location in patent: Paragraph 0057; 0058; 0059; 0064; 0065
[5] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981, vol. 20, # 5, p. 404 - 406
2,3,5-Triphenyltetrazolium chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3,5-Triphenyltetrazolium chloride manufacturers
- Product
- RT
- Price
- US $85.00/box
- Min. Order
- 1box
- Purity
- 99
- Supply Ability
- 10000
- Release date
- 2025-11-03
- Product
- 2,3,5-Triphenyltetrazolium chloride 298-96-4
- Price
- US $2.20-8.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons
- Release date
- 2025-07-08
- Product
- 2,3,5-Triphenyltetrazolium chloride 298-96-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 3500kg/month
- Release date
- 2021-09-10