ChemicalBook > CAS DataBase List > PAF (C18)

PAF (C18)

Product Name
PAF (C18)
CAS No.
74389-69-8
Chemical Name
PAF (C18)
Synonyms
C18 PAF;PAF (C18);ro14-8161;C18-02:0 PC;PAF (C18),99%;c18-paf-acether;PLATELET ACTIVATING FACTOR-18;PLATELET ACTIVATING FACTOR (C18);hydroxide,innersalt,4-oxide,(r)-thyl;1-O-STEARYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CBNumber
CB8371788
Molecular Formula
C28H58NO7P
Formula Weight
551.74
MOL File
74389-69-8.mol
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PAF (C18) Property

storage temp. 
-20°C
solubility 
chloroform: 10 mg/mL
form 
powder
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29310099
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
60910
Product name
PAF C-18
Purity
≥97%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
60910
Product name
PAF C-18
Purity
≥97%
Packaging
10mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
60910
Product name
PAF C-18
Purity
≥97%
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
60910
Product name
PAF C-18
Purity
≥97%
Packaging
25mg
Price
$257
Updated
2024/03/01
AK Scientific
Product number
1976AH
Product name
1-O-Octadecyl-2-Acetyl-Sn-Glycero-3-Phosphocholine
Packaging
25mg
Price
$383
Updated
2021/12/16
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PAF (C18) Chemical Properties,Usage,Production

Chemical Properties

white solid

Uses

C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.

Uses

C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.

Definition

ChEBI: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaine in which the 1-alkyl and 2-acyl groups are specified as octacdecyl and acetyl respectively

General Description

C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.

Biochem/physiol Actions

C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18-PAF), a platelet-activating factor (PAF) facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis. C18-PAF exhibits neurotoxic effects by initiating caspase-independent death in PAF receptor-deficient neurons.

PAF (C18) Preparation Products And Raw materials

Raw materials

Preparation Products

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PAF (C18) Suppliers

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74389-69-8, PAF (C18)Related Search:

2-O-METHYL PAF C-18 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DINONADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE 1-STEAROYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE LYSO-PAF (C18) 2-O-METHYL PAF C-18 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE PAF (C18) 1-stearoyl-2-linoleoylphosphatidylcholine 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE ENANTIO-PAF (C18) DEHYDRO-LYSO-PAF (C18) 1-O-Octadecyl-2-acetyl-sn-glycero-3-phosphocholine, PAF(C18) PAF C-18:1,Dehydro-PAF(C18), L-α-Phosphatidylcholine, β-acetyl-γ-O-(octadec-9-cis-enyl),DEHYDRO-PAF (C18) LYSOLECITHIN PAF(C18)

  • PAF (C18)
  • PLATELET ACTIVATING FACTOR-18
  • PLATELET ACTIVATING FACTOR (C18)
  • 1-o-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
  • 1-o-stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
  • L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-OCTADECYL
  • C18-02:0 PC
  • C18 PAF
  • PAF (C18) (1-O-OCTADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE)
  • 3,5,9-trioxo-4-phosphaheptacosan-1-aminium,7-(acetyloxy)-4-hydroxy-n,n,n-trime
  • c18-paf-acether
  • hydroxide,innersalt,4-oxide,(r)-thyl
  • ro14-8161
  • 1-O-STEARYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-OCTADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-OCTADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-OCTADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 1-O-OCTADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-OCTADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • PHOSPHATIDYL CHOLINE, BETA-ACETYL-GAMMA-O-(OCTADEC-9-CIS-ENYL))
  • 1-0-Octadecyl-2-acetoyl-Sn-glycero-3-phosphocholine
  • 1-cis-9-octadecenyl-2-acetyl-sn-glycero-3-phosphocholine
  • PAF (C18),99%
  • 74389-69-8
  • C28H58NO7P