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Gomisin A

Product Name
Gomisin A
CAS No.
58546-54-6
Chemical Name
Gomisin A
Synonyms
D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
CBNumber
CB8374224
Molecular Formula
C23H28O7
Formula Weight
416.47
MOL File
58546-54-6.mol
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Gomisin A Property

Melting point:
88.5°C
Boiling point:
454.79°C (rough estimate)
Density 
1.1772 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
powder to crystal
pka
14.58±0.40(Predicted)
color 
White to Light yellow
LogP
4.770 (est)
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Safety

Safety Statements 
24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

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N-Bromosuccinimide Price

TCI Chemical
Product number
G0537
Product name
Gomisin A
Packaging
5MG
Price
$72
Updated
2024/03/01
TCI Chemical
Product number
G0537
Product name
Gomisin A
Packaging
25MG
Price
$258
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
10mg
Price
$169
Updated
2024/03/01
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Gomisin A Chemical Properties,Usage,Production

Description

Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .

Chemical Properties

White powder

Uses

Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.

Gomisin A Preparation Products And Raw materials

Raw materials

Preparation Products

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Gomisin A Suppliers

Americas 1 China 186 Europe 1 Germany 1 India 2 Japan 3 United Kingdom 5 United States 24 Global 223
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from Gomisin A manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Gomisin A 58546-54-6
Price
US $0.00-0.00/mg
Min. Order
20mg
Purity
98% HPLC
Supply Ability
100kg
Release date
2022-10-13
Hebei Duling International Trade Co. LTD
Product
Gomisin A 58546-54-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2022-10-11
Shanghai Standard Technology Co., Ltd.
Product
Gomisin A 58546-54-6
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-15

58546-54-6, Gomisin ARelated Search:

Gomisin C(Schisantherin A) Schisandrin A Nortropine GOMISIN N Schisandrin Silibinin Ginkgo biloba extract WUWEIZISU C (5S)-6α,7β-Dimethyl-1,2,3,11,12-pentamethoxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β,10-triol 5-benzoate 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer SCHISANTHERIN C 98+% HPLC Gomisin K3 GOMISIN,GOMISIN C SCHISANDROL B (GOMISIN A)(P),SCHISANDROL B(GOMISIN A) SNAP-N-SHOOT 0.1mg/mL(P),Gomisin A(Schisandrol B) Masoprocol Gomisin B(Schisantherin B) Dihydromyristicin

  • 2,3,13-tetramethoxy-l-stereoisomer
  • benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,5,6,7,8-tetrahydro-6,7-dimethy
  • wuweizialcoholb
  • wuweizichunb
  • BESIGOMISIN
  • GOMISIN A
  • SCHISANDROL B
  • SCHIZANDROL B
  • Besigomsin
  • Besigomsin (jan/inn)
  • D01752
  • Gomisin A/Schisandrin
  • (6S,7S)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6β,7β-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6α-ol
  • TJN-101
  • Schisandrol B (Gomisin-A
  • Schizandrol B, froM Schisandra chinensis
  • Schizandrol B, 98%, from Schisandra chinensis (Turcz.) Baill.
  • Gomisin A Standard
  • Grifola frondosa (Dicks.) Gray
  • Grifola frondsa
  • Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
  • Schizandrol B，Gomisin A
  • (6S,7S)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol
  • (6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • Schisandrin ethyl alcohol
  • (6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • 58546-54-6
  • 58546-54-8
  • C23H28O7
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Miscellaneous Natural Products