Gomisin A
- Product Name
- Gomisin A
- CAS No.
- 58546-54-6
- Chemical Name
- Gomisin A
- Synonyms
- D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
- CBNumber
- CB8374224
- Molecular Formula
- C23H28O7
- Formula Weight
- 416.47
- MOL File
- 58546-54-6.mol
Gomisin A Property
- Melting point:
- 88.5°C
- Boiling point:
- 454.79°C (rough estimate)
- Density
- 1.1772 (rough estimate)
- refractive index
- 1.5300 (estimate)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- powder to crystal
- pka
- 14.58±0.40(Predicted)
- color
- White to Light yellow
- LogP
- 4.770 (est)
Safety
- Safety Statements
- 24/25
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- G0537
- Product name
- Gomisin A
- Packaging
- 5MG
- Price
- $72
- Updated
- 2024/03/01
- Product number
- G0537
- Product name
- Gomisin A
- Packaging
- 25MG
- Price
- $258
- Updated
- 2024/03/01
- Product number
- 25149
- Product name
- Schisandrol B
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 25149
- Product name
- Schisandrol B
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 25149
- Product name
- Schisandrol B
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $169
- Updated
- 2024/03/01
Gomisin A Chemical Properties,Usage,Production
Description
Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .
Chemical Properties
White powder
Uses
Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.
Gomisin A Preparation Products And Raw materials
Raw materials
Preparation Products
Gomisin A Suppliers
- Tel
- 400-186-5138 13341702378
- Fax
- QQ:190129269
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- Country
- China
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- 1008
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- 58
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- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
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- China
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- +86-21-20908456
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- 021-58180499
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- China
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- 400-6009262 16621234537
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- 021-64823266
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- China
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- 14103
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- 4009903999 13355009207
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- 0539-6365991
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- China
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- 86-28-85159085
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- 86-28-85152372
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- China
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- +86-0755-89668383
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- +86-0755-89594066/4038
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- China
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- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
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- China
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- 9387
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- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
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- Tel
- 0411-62910999 13889544652
- meilunui@163.com
- Country
- China
- ProdList
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View Lastest Price from Gomisin A manufacturers
- Product
- Gomisin A 58546-54-6
- Price
- US $0.00-0.00/mg
- Min. Order
- 20mg
- Purity
- 98% HPLC
- Supply Ability
- 100kg
- Release date
- 2022-10-13
- Product
- Gomisin A 58546-54-6
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-15
- Product
- Gomisin A 58546-54-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12