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Gomisin A

Product Name
Gomisin A
CAS No.
58546-54-6
Chemical Name
Gomisin A
Synonyms
D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
CBNumber
CB8374224
Molecular Formula
C23H28O7
Formula Weight
416.47
MOL File
58546-54-6.mol
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Gomisin A Property

Melting point:
88.5°C
Boiling point:
454.79°C (rough estimate)
Density 
1.1772 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
powder to crystal
pka
14.58±0.40(Predicted)
color 
White to Light yellow
LogP
4.770 (est)
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Safety

Safety Statements 
24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
G0537
Product name
Gomisin A
Packaging
5MG
Price
$72
Updated
2024/03/01
TCI Chemical
Product number
G0537
Product name
Gomisin A
Packaging
25MG
Price
$258
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
25149
Product name
Schisandrol B
Purity
≥98%
Packaging
10mg
Price
$169
Updated
2024/03/01
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Gomisin A Chemical Properties,Usage,Production

Description

Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .

Chemical Properties

White powder

Uses

Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.

Gomisin A Preparation Products And Raw materials

Raw materials

Preparation Products

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Gomisin A Suppliers

Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-186-5138 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1008
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Aktin Chemicals, Inc.
Tel
86-28-85159085
Fax
86-28-85152372
Email
info@aktinchem.com
Country
China
ProdList
297
Advantage
62
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
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View Lastest Price from Gomisin A manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Gomisin A 58546-54-6
Price
US $0.00-0.00/mg
Min. Order
20mg
Purity
98% HPLC
Supply Ability
100kg
Release date
2022-10-13
Shanghai Standard Technology Co., Ltd.
Product
Gomisin A 58546-54-6
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-15
Career Henan Chemical Co
Product
Gomisin A 58546-54-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

58546-54-6, Gomisin ARelated Search:


  • 2,3,13-tetramethoxy-l-stereoisomer
  • benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,5,6,7,8-tetrahydro-6,7-dimethy
  • wuweizialcoholb
  • wuweizichunb
  • BESIGOMISIN
  • GOMISIN A
  • SCHISANDROL B
  • SCHIZANDROL B
  • Besigomsin
  • Besigomsin (jan/inn)
  • D01752
  • Gomisin A/Schisandrin
  • (6S,7S)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6β,7β-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6α-ol
  • TJN-101
  • Schisandrol B (Gomisin-A
  • Schizandrol B, froM Schisandra chinensis
  • Schizandrol B, 98%, from Schisandra chinensis (Turcz.) Baill.
  • Gomisin A Standard
  • Grifola frondosa (Dicks.) Gray
  • Grifola frondsa
  • Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
  • Schizandrol B,Gomisin A
  • (6S,7S)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol
  • (6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • Schisandrin ethyl alcohol
  • (6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
  • Schisandrol B-RM
  • 58546-54-6
  • 58546-54-8
  • C23H28O7
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Miscellaneous Natural Products