ChemicalBook > CAS DataBase List > Clorsulon

Clorsulon

Product Name
Clorsulon
CAS No.
60200-06-8
Chemical Name
Clorsulon
Synonyms
chlorsulon;CLORSULON USP;orsuL;MK-401;l631529;curatrem;CLORSULON;keluosuolong;Clorsulon (MK-401;Clorsulon (200 mg)
CBNumber
CB8375438
Molecular Formula
C8H8Cl3N3O4S2
Formula Weight
380.66
MOL File
60200-06-8.mol
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Clorsulon Property

Melting point:
194-203°C
Boiling point:
651.7±65.0 °C(Predicted)
Density 
1.800±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.16±0.60(Predicted)
color 
White
CAS DataBase Reference
60200-06-8(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
CZ9090000
HS Code 
29350090
Toxicity
LD50 in mice (mg/kg): 761 i.p.; >10,000 orally (Ostlind)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
33973
Product name
Clorsulon
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
1140702
Product name
Clorsulon
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Cayman Chemical
Product number
30288
Product name
Clorsulon
Packaging
50mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
30288
Product name
Clorsulon
Packaging
100mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
30288
Product name
Clorsulon
Packaging
250mg
Price
$239
Updated
2024/03/01
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Clorsulon Chemical Properties,Usage,Production

Description

Clorsulon is a sulfonamide antiparasitic agent. It induces swelling and blebbing and reduces motility of F. hepatica mature flukes when used at a concentration of 10 μg/ml. In vivo, clorsulon (3.5-15 mg/kg) reduces the number of flukes in a goat model of F. hepatica infection. It completely eradicates naturally acquired F. hepatica adult flukes in sheep and cattle when administered at a dose of 7 mg/kg. Formulations containing clorsulon have been used in the treatment of liver flukes in sheep and cattle.

Chemical Properties

Crystalline Solid

Uses

analgesic, antiinflammatory

Uses

A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes).

Definition

ChEBI: 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide is a sulfonamide and a member of benzenes.

brand name

Curatrem [Veterinary] (Merial).

Veterinary Drugs and Treatments

Clorsulon is approved for use in the treatment of immature and adult forms of Fasciola hepatica (Liver fluke) in cattle. It is not effective against immature flukes less than 8 weeks old. It also has activity against Fasciola gigantica. Although not approved, the drug has been used in practice in various other species (e.g., sheep, llamas). It has activity against F. magna in sheep, but is not completely effective in eradicating the organism after a single dose, thus severely limiting its clinical usefulness against this parasite. Clorsulon is also not effective against the rumen fluke (Paramphistomum).

Clorsulon Preparation Products And Raw materials

Raw materials

Preparation Products

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Clorsulon Suppliers

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View Lastest Price from Clorsulon manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Clorsulon 60200-06-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
100kg
Release date
2021-10-21
Nantong Guangyuan Chemicl Co,Ltd
Product
Clorsulon 60200-06-8
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-16
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
Clorsulon 60200-06-8
Price
US $0.00-0.00/g
Min. Order
100g
Purity
99%
Supply Ability
20 tons
Release date
2023-08-03

60200-06-8, ClorsulonRelated Search:

Trichlorovinylsilane Glycine 6-Aminocaproic acid Benzenesulfonamide 3-Aminophenol ALTRENOGEST 3-Aminobenzenesulfonamide Tris(hydroxymethyl)aminomethane Trichloroethylene Sulfanilamide 2-Aminobenzenesulfonamide 1,1-DICHLOROPROPENE 1,2-DICHLOROPROPENE Clorsulon, Vetranal Foramsulfuron 1,1,2-TRICHLOROPROPENE BETA-CHLOROSTYRENE P-SULFONAMIDO STYRENE

  • 4-amino-6-(trichloroethenyl)-3-benzenedisulfonamide
  • curatrem
  • keluosuolong
  • l631529
  • 4-AMINO-6-(TRICHLORO-ETHENYL)-1,3-BENZENEDISULFONAMIDE
  • 4-AMINO-6-TRICHLOROVINYL-1,3-BENZENEDISULFONAMIDE
  • 4-AMINO-6-(TRICHLOROVINYL)-M-BENZENEDISULFONAMIDE
  • 1,3-Benzenedisulfonamide, 4-amino-6-(trichloroethenyl)-
  • chlorsulon
  • CLORSULON USP
  • 4-AMINO-6-(TRICHLOROETHENYL)-1,3-BENZENEDISULPHONAMIDE
  • MK-401
  • 4-AMINO-6-(1,2,2-TRICHLOROVINYL)BENZENE-1,3-DISULFONAMIDE
  • 4-Amino-6-(1,2,2-trichloroethenyl)-1,3-benzenedisulfonamide
  • CLORSULON
  • 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide
  • 4-azanyl-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide
  • Clorsulon (200 mg)
  • Foramsulfuron, Pestanal
  • 1,3-BenzenedisulfonaMide,4-aMino-6-(1,2,2-trichloroethenyl)-
  • orsuL
  • 4-Amino-6-(trichlorovinyl)benzene-1,3-disulfonamide
  • Clorsulon (MK-401
  • ClorsulonQ: What is Clorsulon Q: What is the CAS Number of Clorsulon Q: What is the storage condition of Clorsulon Q: What are the applications of Clorsulon
  • Clorsulon (1140702)
  • Clorsulon in methanol
  • C11691400 Clorsulon
  • Clorsulon, 10 mM in DMSO
  • 60200-06-8
  • 60200-02-8
  • C8H8Cl3N3O4S2
  • ZOMAX
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  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds