4-(Chloromethyl)pyridine hydrochloride
- Product Name
- 4-(Chloromethyl)pyridine hydrochloride
- CAS No.
- 1822-51-1
- Chemical Name
- 4-(Chloromethyl)pyridine hydrochloride
- Synonyms
- 4-PICOLYL CHLORIDE HYDROCHLORIDE;4-Picolyl chloride;TIMTEC-BB SBB003917;4-Picolyl chloride h;4-(Chloromethyl)pyridine HCL;4-Plcolyl Chloride Hydrochloride;4-(Chloromethyl) Pyridine HCL 99%;4-(Chloromethyl)pyridine hydrochl;4-(CHLOROMETHYL)PYRIDINIUM CHLORIDE;4-Picolyl chloride hydrochloride,97%
- CBNumber
- CB8380214
- Molecular Formula
- C6H6ClN.ClH
- Formula Weight
- 164.03
- MOL File
- 1822-51-1.mol
4-(Chloromethyl)pyridine hydrochloride Property
- Melting point:
- 166-173 °C(lit.)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- soluble in DMSO, Methanol
- form
- Fine Crystalline Powder
- color
- Yellow to orange
- Water Solubility
- 750 g/L (20 ºC)
- Sensitive
- Hygroscopic
- BRN
- 3689154
- CAS DataBase Reference
- 1822-51-1(CAS DataBase Reference)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34-4-22-36/37/38
- Safety Statements
- 26-36/37/39-45-36
- RIDADR
- UN 3261 8/PG 3
- WGK Germany
- 3
- F
- 3-10
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- P43807
- Product name
- 4-(Chloromethyl)pyridine hydrochloride
- Purity
- 97%
- Packaging
- 10g
- Price
- $24.8
- Updated
- 2024/03/01
- Product number
- P43807
- Product name
- 4-(Chloromethyl)pyridine hydrochloride
- Purity
- 97%
- Packaging
- 100g
- Price
- $160
- Updated
- 2024/03/01
- Product number
- C0805
- Product name
- 4-(Chloromethyl)pyridine Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $113
- Updated
- 2024/03/01
- Product number
- C0805
- Product name
- 4-(Chloromethyl)pyridine Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 250g
- Price
- $675
- Updated
- 2024/03/01
- Product number
- A12859
- Product name
- 4-(Chloromethyl)pyridine hydrochloride, 98%
- Packaging
- 5g
- Price
- $31.65
- Updated
- 2024/03/01
4-(Chloromethyl)pyridine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
YELLOW TO ORANGE FINE CRYSTALLINE POWDER
Uses
It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst?15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Purification Methods
Purify it by recrystallisation from EtOH or EtOH/dry Et2O. It melts between 171o and 175o, and the clear melt resolidifies on further heating at 190o and turns red to black at 280o but does not melt again. The picrate-hydrochloride (prepared in EtOH) has m 146-147o. The free base is an oil. [Mosher & Tessieri J Am Chem Soc 73 4925 1951, Beilstein 20 III/IV 2752.]
4-(Chloromethyl)pyridine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(Chloromethyl)pyridine hydrochloride manufacturers
- Product
- 4-(Chloromethyl)pyridine hydrochloride 1822-51-1
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-05
- Product
- 4-(Chloromethyl)pyridine hydrochloride 1822-51-1
- Price
- US $15.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-24
- Product
- 4-(Chloromethyl)pyridine hydrochloride 1822-51-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-10-11