Meisoindigo

Product Name: Meisoindigo
CAS No.: 97207-47-1
Chemical Name: Meisoindigo
Synonyms: CS-1454;Natura-α;Dian III;Natura-α;MEISOINDIGO;3'-digallate;Theaflavine-3;Meisoindigo, >96%;Methylisoindigotin;Meisoindigo, >=98%
CBNumber: CB8394558
Molecular Formula: C17H12N2O2
Formula Weight: 276.29
MOL File: 97207-47-1.mol

More

Less

Meisoindigo Property

Melting point:: 236-237°C
Boiling point:: 482.0±45.0 °C(Predicted)
Density: 1.381±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL in DMSO with ultrasonic
form: powder to crystal
pka: 11.62±0.20(Predicted)
color: Orange to Brown to Dark red

More

Less

Safety

HS Code: 2933.79.1500

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M3082
Product name: Meisoindigo
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: M3082
Product name: Meisoindigo
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $410
Updated: 2024/03/01

Cayman Chemical

Product number: 18007
Product name: Meisoindigo
Purity: ≥95%
Packaging: 500μg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18007
Product name: Meisoindigo
Purity: ≥95%
Packaging: 1mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 18007
Product name: Meisoindigo
Purity: ≥95%
Packaging: 5mg
Price: $341
Updated: 2024/03/01

More

Less

Meisoindigo Chemical Properties,Usage,Production

Description

Meisoindigo is a derivative of indirubin that has anticancer activity. It inhibits the growth of NB4, HL-60, and U937 leukemia and primary acute myeloid leukemia (AML) cells when used at concentrations of 5 and 10 μM. It also halts the cell cycle at the G₀/G₁ phase and induces apoptosis in leukemia cell lines and primary AML cells, induces myeloid differentiation, and potentiates the effects of cytarabine and idarubicin . Meisoindigo (10 μM) also induces apoptosis, decreases adherence, and decreases the expression of vascular cell adhesion molecule-1 (VCAM-1) in ECV304 human vein endothelial cells. Meisoindigo (50-150 mg/kg per day) decreases spleen size in an HL-60 mouse xenograft model of AML in a dose-dependent manner.

Chemical Properties

mp 236-237°C

Uses

Meisoindigo is a 5-HT3 receptor antagonist prevents acute nausea and vomiting associated with emetogenic cancer chemotherapy

Uses

Meisoindigo shows strong anti-proliferation effect against gemcitabine-resistant Pancreatic ductal adenocarcinoma (PDACs).

References

[1] lee cc, lin cp, lee yl, wang gc, cheng yc, liu he. meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia. leuk lymphoma. 2010 may;51(5):897-905.

Meisoindigo Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Meisoindigo Suppliers

Americas 1 China 114 Europe 1 Finland 1 Germany 1 India 2 Japan 1 United States 21 Global 142

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973 13515979683
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1079
Advantage: 58

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23680
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23662
Advantage: 75

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7856
Advantage: 58

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

More

Less

View Lastest Price from Meisoindigo manufacturers

Dideu Industries Group Limited

Product: Meisoindigo 97207-47-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-01

Shaanxi Dideu Medichem Co. Ltd

Product: Meisoindigo 97207-47-1
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

Career Henan Chemical Co

Product: Meisoindigo 97207-47-1
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

97207-47-1, MeisoindigoRelated Search:

4-Methyl-2-pentanone Dihydromyrcenol 1-(2,6-Dichlorophenyl)indolin-2-one Basic Violet 1 Methyl tetrahydrophthalic anhydride Methanol Mesotrione Methyl acrylate Acetonitrile cis-Octahydro-isoindole Paraquat dichloride Methylparaben Tetramethylammonium hydroxide Kresoxim-methyl Methyl 2-Butanone Indole Meisoindigo

1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)-DIONE

3-(1,2-dihydro-2-oxo-3h-indol-3-ylidene)-1,3-dihydro-1-methyl-2h-indol-2-one

MEISOINDIGO

N-methylisoindigotin

Dian III

Methylisoindigotin

Natura-α

Meisoindigo 3-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl-2H-indol-2-one

Methylisoindigotin Meisoindigo

Meisoindigo, >=98%

Meisoindigo, >96%

CS-1454

Meisoindigo(Natura-

DIAN III; N-METHYLISOINDIGOTIN; NATURA-Α

2H-Indol-2-one, 3-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl-

(3E)-1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one

Meisoindigo USP/EP/BP

1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one

Natura-α

3'-digallate

Theaflavine-3

(E)-1-methyl-[3,3'-biindolinylidene]-2,2'-dione

1-Methyl-[3,3'-biindolinylidene]-2,2'-dione

97207-47-1

Inhibitors