N-Ethylcyclohexylamine Property

Melting point:

-15°C (estimate)

Boiling point:

165 °C (lit.)

Density 

0.844 g/mL at 25 °C (lit.)

vapor density 

4.4 (vs air)

vapor pressure 

2 mm Hg ( 20 °C)

refractive index 

n20/D 1.452(lit.)

Flash point:

111 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

Liquid

pka

11.16±0.20(Predicted)

color 

Clear colorless to light yellow

explosive limit

7.6%

BRN 

2070280

LogP

1.027 at 25℃ and pH7.75

CAS DataBase Reference

5459-93-8(CAS DataBase Reference)

NIST Chemistry Reference

Cyclohexanamine, N-ethyl-(5459-93-8)

EPA Substance Registry System

N-Ethylcyclohexylamine (5459-93-8)

Safety

Hazard Codes 

C

Risk Statements 

10-20/21/22-35

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2734 8/PG 2

WGK Germany 

3

RTECS 

GX1225000

Autoignition Temperature

473 °F

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29213000

Hazardous Substances Data

5459-93-8(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

N-Ethylcyclohexylamine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Uses

Intermediate in production of herbicides and pharmaceuticals.

Uses

N-Ethylcyclohexylamine can be used in the synthesis of a series of isatin-N-Mannich bases.

Production Methods

N-Ethylcyclohexylamine is produced by hydrogenation of ethylaniline at 180 ℃ and 6 MPa or by amination of cyclohexanone under hydrogenation conditions in the presence of ethylamine. The amine is a starting material for the preplant sugar beet, grass, and spinach herbicide cycloate (Zeneca's Ro-Neet), which is obtained by converting N-ethylcyclohexylamine into S-ethyl-N-ethyl-N-cyclohexylthiocarbamate. A minor use of N-ethylcyclohexylamine is for vulcanization accelerators.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 6749, 1996 DOI: 10.1016/S0040-4039(96)01458-X

General Description

A clear colorless liquid with an ammonia-like odor. Floats on water and slightly soluble in water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Highly flammable. Slightly soluble in water.

Reactivity Profile

N-Ethylcyclohexylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Corrosive and toxic.

Health Hazard

Inhalation of high concentration of vapor will produce irritation of the respiratory tract and lungs. Inhalation of large quantities of vapor may be fatal.

Fire Hazard

Behavior in Fire: Dangerous when exposed to heat or flame. Can react vigorously with oxidizing materials.

Safety Profile

Moderately toxic by ingestion, inhalation, and skin contact. A severe skin and eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fKe, use alcohol foam, mist, spray, dry chemical. See also AMINES