PYRROLIDIN-1-YL-ACETIC ACID

Product Name: PYRROLIDIN-1-YL-ACETIC ACID
CAS No.: 37386-15-5
Chemical Name: PYRROLIDIN-1-YL-ACETIC ACID
Synonyms: AKOS BC-0363;AKOS BBS-00000323;RARECHEM AL BO 0350;SALOR-INT L481092-1EA;1-PYRROLIDINEACETIC ACID;N-PYRROLIDINOACETIC ACID;1-PYRROLIDINYLACETIC ACID;1-Pyrroltdinylacetic acid;Pyrroldin-1-yl-acetic acid;PYRROLIDIN-1-YL-ACETIC ACID
CBNumber: CB8412478
Molecular Formula: C6H11NO2
Formula Weight: 129.16
MOL File: 37386-15-5.mol

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PYRROLIDIN-1-YL-ACETIC ACID Property

Melting point:: 184-185 °C
Boiling point:: 233.8±23.0 °C(Predicted)
Density: 1.153±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly, Sonicated, Heated), Methanol (Slightly)
form: Solid
pka: 2.47±0.10(Predicted)
color: Pale Yellow
InChI: InChI=1S/C6H11NO2/c8-6(9)5-7-3-1-2-4-7/h1-5H2,(H,8,9)
InChIKey: IPXNXMNCBXHYLQ-UHFFFAOYSA-N
SMILES: N1(CC(O)=O)CCCC1

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L481092
Product name: 1-PYRROLIDINYLACETIC ACID
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: L481092
Product name: 1-PYRROLIDINYLACETIC ACID
Purity: Aldrich
Packaging: 250mg
Price: $179
Updated: 2024/03/01

TRC

Product number: P998495
Product name: 1-PyrrolidineaceticAcid
Packaging: 2.5g
Price: $275
Updated: 2021/12/16

Matrix Scientific

Product number: 027154
Product name: Pyrrolidin-1-ylacetic acid
Packaging: 500mg
Price: $153
Updated: 2021/12/16

AK Scientific

Product number: Y8903
Product name: Pyrrolidin-1-ylaceticacid
Packaging: 1g
Price: $111
Updated: 2021/12/16

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PYRROLIDIN-1-YL-ACETIC ACID Chemical Properties,Usage,Production

Uses

1-?Pyrrolidineacetic Acid is a useful reactant and reagent in organic reactions. It can be found used in cosmetic products such as wrinkle-?preventive?/ameliorating products.

Synthesis

22041-19-6

37386-15-5

b) Synthesis of 2-(pyrrolidin-1-yl)acetic acid: ethyl 2-(pyrrolidin-1-yl)acetate (2 g, 12.7 mmol, 1.0 eq.) was dissolved in 8N HCl and the reaction was stirred for 16 hrs. at 95°C. Upon completion of the reaction, the mixture was concentrated, the reaction was quenched and extracted as in Intermediate Example 15(b). Subsequently, the solvent was removed by distillation to afford the target product 2-(pyrrolidin-1-yl)acetic acid in 91% (1.5 g) yield. The product was analyzed by LC-MS (ESI): calculated mass 129.1; measured mass 130.1 [M + H]+ (retention time: 0.26 min).

References

[1] Patent: WO2013/53983, 2013, A1. Location in patent: Page/Page column 40
[2] Patent: US2015/11548, 2015, A1. Location in patent: Paragraph 0161
[3] Liebigs Annalen der Chemie, 1983, # 6, p. 950 - 961

PYRROLIDIN-1-YL-ACETIC ACID Preparation Products And Raw materials

Raw materials

Ethanol Bromoacetic acid Sodium hydroxide Pyrrolidine

Preparation Products

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PYRROLIDIN-1-YL-ACETIC ACID Suppliers

China 71 Germany 4 India 2 Russia 1 South Korea 1 Switzerland 1 United Kingdom 2 United States 11 Global 93

Accela ChemBio Inc.

Tel: +1(858) 699-3322
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Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
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Alchem Pharmtech,Inc.

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Matrix Scientific

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3B Scientific Corporation

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Anvia Chemicals, LLC

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HONEST JOY HOLDINGS LIMITED

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View Lastest Price from PYRROLIDIN-1-YL-ACETIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: PYRROLIDIN-1-YL-ACETIC ACID 37386-15-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-20

Shaanxi Dideu New Materials Co. Ltd

Product: PYRROLIDIN-1-YL-ACETIC ACID 37386-15-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-18

37386-15-5, PYRROLIDIN-1-YL-ACETIC ACIDRelated Search:

ETHYL PYRROLIDINOACETATE PHENYL-PYRROLIDIN-1-YL-ACETIC ACID METHYL1-PYRROLIDINEACETATE (R)-METHYL 2-(PYRROLIDIN-2-YL)ACETATE METHYL (2S)-PYRROLIDIN-2-YLACETATE 2-(pyrrolidin-3-yl)acetic acid (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID N-beta-(t-Butyloxycarbonyl)-L-homoproline, (S)-N-t-Butyloxycarbonyl-2-(pyrrolidin-2-yl)acetic acid 2-(1-(TERT-BUTOXYCARBONYL)PYRROLIDIN-3-YL)ACETIC ACID L-beta-Homoproline, (S)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride (S)-(1-Boc-pyrrolidin-3-yl)acetic acid 2-pyrrolidin-1-ylacetic acid N-beta-(9-Fluorenylmethyloxycarbonyl)-L-homoproline, (S)-N-(9-Fluorenylmethyloxycarbonyl)-2-(pyrrolidin-2-yl)acetic acid (2,5-DIOXO-PYRROLIDIN-1-YL)-ACETIC ACID CARBOMETHOXYCARBONYL-D-PRO-D-PHE BENZYL ESTER CARBOMETHOXYCARBONYL-PRO-PHE-OBZL 2-(3,5-DIOXO-4-AZATRICYCLO[5.2.1.0(2,6)]DEC-8-EN-4-YL)-4-METHYLPENTANOIC ACID 4-(4-METHYLPHENYL)-4-OXO-2-(1-PYRROLIDINYL)BUTANOIC ACID

AKOS BBS-00000323

AKOS BC-0363

1-PYRROLIDINEACETIC ACID

1-PYRROLIDINYLACETIC ACID

N-PYRROLIDINOACETIC ACID

SALOR-INT L481092-1EA

PYRROLIDIN-1-YL-ACETIC ACID

RARECHEM AL BO 0350

Pyrroldin-1-yl-acetic acid

1-Pyrrolidinylacetic acid N-Pyrrolidinoacetic acid

pyrrolidin-1-ylacetic acid(SALTDATA: FREE)

1-Pyrroltdinylacetic acid

2-(1-Pyrrolidyl)acetic Acid

Eravacycline intermediate F

37386-15-5