1-Methylpyrazole

Product Name: 1-Methylpyrazole
CAS No.: 930-36-9
Chemical Name: 1-Methylpyrazole
Synonyms: 1-METHYL-1H-PYRAZOLE;methylpyrazole;AKOS PAO-1140;1-Methypyrazole;N-METHYLPYRAZOLE;1-METHYLPYRAZOLE;Methylpyrazole,98%;Pyrazole, 1-methyl-;1-Methylpyrazole>1-Methylpyrazole,97%
CBNumber: CB8430465
Molecular Formula: C4H6N2
Formula Weight: 82.1
MOL File: 930-36-9.mol

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1-Methylpyrazole Property

Melting point:: 36.5°C (estimate)
Boiling point:: 127 °C
Density: 0.988 g/mL at 20 °C (lit.)
refractive index: n20/D 1.477
Flash point:: 35 °C
storage temp.: Inert atmosphere,Room Temperature
Water Solubility: Soluble in water
pka: 2.25±0.10(Predicted)
form: Liquid
color: Clear colorless to light yellow
BRN: 105207
InChI: InChI=1S/C4H6N2/c1-6-4-2-3-5-6/h2-4H,1H3
InChIKey: UQFQONCQIQEYPJ-UHFFFAOYSA-N
SMILES: N1(C)C=CC=N1
CAS DataBase Reference: 930-36-9(CAS DataBase Reference)
NIST Chemistry Reference: 1-methylpyrazole(930-36-9)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38
Safety Statements: 26-37/39-16
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
F: 10
HazardClass: 3
PackingGroup: III
HS Code: 29331990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 91493
Product name: 1-Methylpyrazole
Purity: ≥99.0% (GC)
Packaging: 10g
Price: $113
Updated: 2024/03/01

TCI Chemical

Product number: M0969
Product name: 1-Methylpyrazole
Purity: >98.0%(GC)
Packaging: 5g
Price: $21
Updated: 2024/03/01

TCI Chemical

Product number: M0969
Product name: 1-Methylpyrazole
Purity: >98.0%(GC)
Packaging: 25g
Price: $83
Updated: 2024/03/01

Alfa Aesar

Product number: L14831
Product name: 1-Methyl-1H-pyrazole, 97+%
Packaging: 5g
Price: $51.65
Updated: 2024/03/01

Alfa Aesar

Product number: L14831
Product name: 1-Methyl-1H-pyrazole, 97+%
Packaging: 25g
Price: $148.65
Updated: 2024/03/01

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1-Methylpyrazole Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

1-Methylpyrazole is a useful synthetic intermediate. It is used to synthesize heteroaryl(fluorophenyl)piperidinylindoles as α1 adrenoceptor antagonists. It is also used to prepare quinazoline derivatives as glucokinase activators.

Definition

ChEBI: A member of the class of pyrazoles that is the 1-methyl derivative of 1H-pyrazole.

Synthesis

1-Methylpyrazole was prepared by the condensation of 1,1,3,3-tetraethoxypropane with methylhydrazine[1].

References

[1] Peggy W. Alley, David A. Shirley. “The Metalation of 1-Phenyl- and 1-Methylpyrazole with n-Butyllithium.” Journal of the American Chemical Society 80 23 (1958): 6271–6274.

1-Methylpyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

5-(Aminomethyl)-1-methyl-1H-pyrazole 97% Ethyl 1-methyl-1H-pyrazole-5-carboxylate 1-Methyl-1H-pyrazole-5-carboxylic acid 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester (1-Methyl-1H-pyrazol-3-yl)methanol

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1-Methylpyrazole Suppliers

Americas 1 Belgium 3 China 287 Europe 3 France 2 Germany 8 India 25 Japan 3 Russia 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 13 United States 42 Global 392

CMS Chemicals Limited

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Fisher Scientific Uk Ltd.

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Melrob Ltd (part of Nordmann)

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Manchester Organics

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Apollo Scientific Ltd.

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Key Organics Limited/Bionet Research

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Carbosynth Limited

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ENDEAVOUR SPECIALITY CHEMICALS LTD.

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Atlantic Research Chemicals Ltd.

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Fluorochem Ltd

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Eurolabs Limited

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Fluorochem Ltd.

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VWR International

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View Lastest Price from 1-Methylpyrazole manufacturers

Hubei Lidu New Material Technology Co., Ltd

Product: METHYLPYRAZOLE 930-36-9
Price: US $0.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 20tons
Release date: 2024-09-18

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 1-Methylpyrazole 930-36-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-10

Hebei Weibang Biotechnology Co., Ltd

Product: 1-Methylpyrazole 930-36-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

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