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N-ACETYLPROCAINAMIDE

Product Name
N-ACETYLPROCAINAMIDE
CAS No.
32795-44-1
Chemical Name
N-ACETYLPROCAINAMIDE
Synonyms
acekainid;acecainide;TIMTEC-BB SBB005970;N-ACETYLPROCAINAMIDE;n-acetyloprokainamid;N-ACETYLPROCAINAMIDE, 99+%;N-ACETYLPROCAINAMIDE USP/EP/BP;4-acetamido-N-(2-(diethylamino)ethyl)benzamide;4’-((2-(diethylamino)ethyl)carbamoyl)acetanilide;4’-((2-(diethylamino)ethyl)carbamoyl)-acetanilid
CBNumber
CB8432449
Molecular Formula
C15H23N3O2
Formula Weight
277.36
MOL File
32795-44-1.mol
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N-ACETYLPROCAINAMIDE Property

Melting point:
138-140 °C(lit.)
Boiling point:
500.0±35.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
soluble1%, clear, colorless to faintly yellow (1N HCl)
pka
14.54±0.46(Predicted)
Merck 
13,20
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3249
WGK Germany 
3
RTECS 
AE1974350
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
269476
Product name
N-Acetylprocainamide
Purity
≥99%
Packaging
250mg
Price
$62.4
Updated
2024/03/01
Sigma-Aldrich
Product number
269476
Product name
N-Acetylprocainamide
Purity
≥99%
Packaging
1g
Price
$176
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0031256
Product name
N-ACETYLPROCAINAMIDE
Purity
95.00%
Packaging
1G
Price
$681.09
Updated
2021/12/16
ChemScene
Product number
CS-4707
Product name
N-Acetylprocainamide
Purity
≥98.0%
Packaging
100mg
Price
$60
Updated
2021/12/16
CSNpharm
Product number
CSN11506
Product name
N-Acetylprocainamide
Packaging
100mg
Price
$48
Updated
2021/12/16
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N-ACETYLPROCAINAMIDE Chemical Properties,Usage,Production

Originator

Acecainide ,ZYF Pharm Chemical

Uses

antiprotozoal

Uses

N-acetylprocainamide (NAPA) was used as a model drug in the study of establishing a quantitative approach to predict the renal clearances of basic drugs using N-1-methylnicotinamide (NMN).

Definition

ChEBI: A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.

Manufacturing Process

1.0 g of p-amino-N-(2-diethylaminoethyl)benzamide is dissolved in chloroform. A few ice cubes are added to the solution. Acetyl chloride is added dropwise with stirring until no more white precipitate forms; the latter is separated by filtering under suction. The precipitate is washed with cold acetone and dried overnight in a vacuum oven at room temperature. The product is dissolved in a minimum amount of hot isopropanol and allowed to precipitate in the cold. The p-acetamido-N-(2-diethylaminoethyl)benzamide hydrochloride, is recrystallized a second time from hot isopropanol, melting point 190°-193°C. The free base is obtained from the hydrochloride by dissolving the latter in water, adjusting the pH to greater than 10 with dilute sodium hydroxide, and adding an equal volume of benzene. After shaking in a separatory funnel, the benzene layer is recovered and evaporated to dryness. So the p-acetamido-N- (2-diethylaminoethyl)benzamide is obtained.

Therapeutic Function

Antiarrhythmic

General Description

The relaxant effects of N-acetylprocainamide on bovine tracheal smooth muscle was studied.

N-ACETYLPROCAINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ACETYLPROCAINAMIDE Suppliers

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View Lastest Price from N-ACETYLPROCAINAMIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-AcetylprocainaMide 32795-44-1
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-11
Dideu Industries Group Limited
Product
N-ACETYLPROCAINAMIDE 32795-44-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-11

32795-44-1, N-ACETYLPROCAINAMIDERelated Search:

p-Acetotoluidide 4-Amino-N-methylbenzamide N-Benzylethylenediamine 4-Amino-N-methylbenzylamine N'-BENZYL-N,N-DIMETHYLETHYLENEDIAMINE N-ACETYLPROCAINAMIDE 4-Acetamidobenzaldehyde 4-Aminobenzylamine 4-METHYLFORMANILIDE procainamide N-ACETYLPROCAINAMIDE HYDROCHLORIDE,N-ACETYLPROCAINAMIDE HCL,N-ACETYLPROCAINAMIDE HYDROCHLORIDEAPPROX 97% N,N,N'-TRIETHYLETHYLENEDIAMINE Cloxacepride p-Aminobenzamide N-{4-[(methylamino)methyl]phenyl}acetamide N1-BENZYL-N2-ETHYLETHANE-1,2-DIAMINE 4-ACETAMIDOBENZYLAMINE 4-AMINO-N-ETHYLBENZAMIDE

  • 4-(acetylamino)-n-(2-(diethylamino)ethyl)-benzamid
  • 4-(acetylamino)-n-[2-(diethylamino)ethyl]-benzamid
  • 4-acetamido-N-(2-(diethylamino)ethyl)benzamide
  • 4’-((2-(diethylamino)ethyl)carbamoyl)-acetanilid
  • 4’-((2-(diethylamino)ethyl)carbamoyl)acetanilide
  • acecainide
  • acekainid
  • n-acetyloprokainamid
  • N-ACETYLPROCAINAMIDE
  • TIMTEC-BB SBB005970
  • N-ACETYLPROCAINAMIDE, 99+%
  • 4-(Acetylamino)-N-[2-(diethylamino)ethyl]benzamide
  • Benzamide, 4-(acetylamino)-N-[2-(diethylamino)ethyl]-
  • N-ACETYLPROCAINAMIDE USP/EP/BP
  • KcsA,N Acetylprocainamide,N-Acetylprocainamide,inhibit,Potassium Channel,NAcetylprocainamide,Inhibitor,Drug Metabolite
  • 32795-44-1
  • C15H23N3O2
  • 4CH3CONHC6H4CONHCH2CH2NC2H52
  • Carbonyl Compounds
  • Amides
  • Building Blocks
  • Organic Building Blocks
  • TINDAMAX
  • Amides
  • Carbonyl Compounds
  • Organic Building Blocks