N-DESMETHYL ROSIGLITAZONE

Product Name: N-DESMETHYL ROSIGLITAZONE
CAS No.: 257892-31-2
Chemical Name: N-DESMETHYL ROSIGLITAZONE
Synonyms: SB 237216;N-DESMETHYL ROSIGLITAZONE;N-Desmethyl Rosiglitazone Solution, 100ppm;5-[[4-[2-(2-pyridinylamino]ethoxy]phenyl]methyl]-2,4-thiazolidinedione;2,4-Thiazolidinedione, 5-[[4-[2-(2-pyridinylamino)ethoxy]phenyl]methyl]-;N-Desmethyl RosiglitazoneQ: What is N-Desmethyl Rosiglitazone Q: What is the CAS Number of N-Desmethyl Rosiglitazone Q: What is the storage condition of N-Desmethyl Rosiglitazone Q: What are the applications of N-Desmethyl Rosiglitazone
CBNumber: CB8433330
Molecular Formula: C17H17N3O3S
Formula Weight: 343.4
MOL File: 257892-31-2.mol

More

Less

N-DESMETHYL ROSIGLITAZONE Property

Melting point:: 177-179°C
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Pale Beige

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 22103
Product name: N-desmethyl Rosiglitazone
Purity: ≥98%
Packaging: 1mg
Price: $104
Updated: 2024/03/01

Cayman Chemical

Product number: 22103
Product name: N-desmethyl Rosiglitazone
Purity: ≥98%
Packaging: 5mg
Price: $395
Updated: 2024/03/01

Cayman Chemical

Product number: 22103
Product name: N-desmethyl Rosiglitazone
Purity: ≥98%
Packaging: 10mg
Price: $656
Updated: 2024/03/01

Usbiological

Product number: D3218-50
Product name: N-Desmethyl Rosiglitazone |
Packaging: 1mg
Price: $460
Updated: 2021/12/16

TRC

Product number: D292165
Product name: N-DesmethylRosiglitazone
Packaging: 2.5mg
Price: $155
Updated: 2021/12/16

More

Less

N-DESMETHYL ROSIGLITAZONE Chemical Properties,Usage,Production

Description

N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Item Nos. 71740 | 71742 | 11884), a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.

Chemical Properties

White Solid

Uses

A metabolite of Rosiglitazone.

Definition

ChEBI: N-desmethylrosiglitazone is an aromatic ether.

References

[1] J M LEHMANN. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).[J]. The Journal of Biological Chemistry, 1995, 270 22: 12953-12956. DOI: 10.1074/jbc.270.22.12953
[2] KWON-BOK KIM . Simultaneous quantification of rosiglitazone and its two major metabolites, N-desmethyl and p-hydroxy rosiglitazone in human plasma by liquid chromatography/tandem mass spectrometry: Application to a pharmacokinetic study[J]. Journal of Chromatography B, 2009, 877 20: Pages 1951-1956. DOI: 10.1016/j.jchromb.2009.05.001

N-DESMETHYL ROSIGLITAZONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-DESMETHYL ROSIGLITAZONE Suppliers

Canada 3 China 20 India 2 United Kingdom 1 United States 9 Global 35

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

257892-31-2, N-DESMETHYL ROSIGLITAZONERelated Search:

5-(4-Fluorobenzyl)-2,4-thiazolidinedione 5-Hydroxy rosiglitazone-d4 5-[[4-[1,1,2,2-tetradeuterio-2-[(5-hydroxypyridin-2-yl)-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Rosiglitazone maleate 5-[4-[N-(2-Pyridylamino)ethoxy]benzylidene]thiazolidine-2,4-dione 5-[[4-[2-[pyridin-2-yl(trideuteriomethyl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione 5-HYDROXY ROSIGLITAZONE Rosiglitazone 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione sodium salt 2,4-Thiazolidinedione DESMETHYL ROSIGLITAZONE-D4 AKOS 92116 ROSIGLITAZONE-5-SULFOXY ROSIGLITAZONE D-TARTRATE N-DESMETHYL ROSIGLITAZONE

SB 237216

N-Desmethyl Rosiglitazone Solution, 100ppm

N-DESMETHYL ROSIGLITAZONE

5-[[4-[2-(2-pyridinylamino]ethoxy]phenyl]methyl]-2,4-thiazolidinedione

2,4-Thiazolidinedione, 5-[[4-[2-(2-pyridinylamino)ethoxy]phenyl]methyl]-

N-Desmethyl RosiglitazoneQ: What is N-Desmethyl Rosiglitazone Q: What is the CAS Number of N-Desmethyl Rosiglitazone Q: What is the storage condition of N-Desmethyl Rosiglitazone Q: What are the applications of N-Desmethyl Rosiglitazone

257892-31-2

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Aromatics

Heterocycles

Sulfur & Selenium Compounds