ChemicalBook > CAS DataBase List > 5-BROMO-2-METHOXYANILINE

5-BROMO-2-METHOXYANILINE

Product Name
5-BROMO-2-METHOXYANILINE
CAS No.
6358-77-6
Chemical Name
5-BROMO-2-METHOXYANILINE
Synonyms
5-bromo-o-anisidine;2-amino-4-bromoanisole;4-Bromo-2-aminoanisole;2-Methoxy-5-bromoaniline;5-BROMO-2-METHOXYANILINE;5-Bromo-2-methoxyaniline >5-Bromo-2-methoxyaniline 98%;5-bromo-2-methoxybenzenamine;5-Bromo-2-methoxyaniline, 97%;Benzenamine, 5-bromo-2-methoxy-
CBNumber
CB8454146
Molecular Formula
C7H8BrNO
Formula Weight
202.05
MOL File
6358-77-6.mol
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5-BROMO-2-METHOXYANILINE Property

Melting point:
94-96°C
Boiling point:
275℃
Density 
1.531
Flash point:
120℃
storage temp. 
2-8°C
pka
3.46±0.10(Predicted)
form 
powder to crystal
color 
Light yellow to Brown
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C7H8BrNO/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,9H2,1H3
InChIKey
OPGNSNDTPPIYPG-UHFFFAOYSA-N
SMILES
C1(N)=CC(Br)=CC=C1OC
CAS DataBase Reference
6358-77-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/21/22-33-43-22
Safety Statements 
26-33-36/37/39-45-36/37
RIDADR 
UN2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
2921490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
750808
Product name
5-Bromo-2-methoxyaniline
Purity
95%
Packaging
5g
Price
$80.8
Updated
2025/07/31
TCI Chemical
Product number
B3828
Product name
5-Bromo-2-methoxyaniline
Purity
>97.0%(T)
Packaging
1g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
B3828
Product name
5-Bromo-2-methoxyaniline
Purity
>97.0%(T)
Packaging
5g
Price
$94
Updated
2025/07/31
Medical Isotopes, Inc.
Product number
37956
Product name
5-Bromo-2-methoxyaniline
Purity
98%
Packaging
5G
Price
$377
Updated
2021/12/16
Matrix Scientific
Product number
009827
Product name
5-Bromo-2-methoxyaniline
Purity
98%
Packaging
100g
Price
$545
Updated
2021/12/16
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5-BROMO-2-METHOXYANILINE Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

5-Bromo-2-methoxyaniline is used as a pharmaceutical intermediate.

Synthesis

33696-00-3

6358-77-6

General procedure for the synthesis of 5-bromo-2-methoxyaniline from 2-nitro-4-bromoanisole: 1. Preparation of Intermediate 11A: An ethanol (65 mL) solution of 4-bromo-1-methoxy-2-nitrobenzene (2.00 g, 8.62 mmol), zinc powder (5.64 g, 86.0 mmol), and ammonium chloride (4.61 g, 86.0 mmol) was stirred for 2 hours at room temperature. 2. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc) and filtered through diatomaceous earth (CELITE). 3. The filtrate was concentrated by evaporation to give Intermediate 11A (1.74 g, 100% yield) as an off-white solid. 4. Mass spectral analysis (LCMS-ESI) of Intermediate 11A showed m/z 202,204 ([M+H]? , [M+2+H]?) , and a retention time (RT) of 0.70 min (Method J).

References

[1] Patent: WO2014/22343, 2014, A1. Location in patent: Paragraph 00169
[2] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 5, p. 1357 - 1366
[3] Journal fuer Praktische Chemie (Leipzig), 1935, vol. <2> 143, p. 18,24
[4] Gazzetta Chimica Italiana, 1932, vol. 62, p. 51,54
[5] Justus Liebigs Annalen der Chemie, 1883, vol. 217, p. 44

5-BROMO-2-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-METHOXYANILINE Suppliers

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View Lastest Price from 5-BROMO-2-METHOXYANILINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-2-METHOXYANILINE 6358-77-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-2-METHOXYANILINE 6358-77-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
5-BROMO-2-METHOXYANILINE 6358-77-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-30

6358-77-6, 5-BROMO-2-METHOXYANILINERelated Search:

4-BROMO-2-NITROANISOLE 4-BROMO-2-FLUORO-6-NITROANISOLE 6-BROMO-2H-1,4-BENZOXAZIN-3(4H)-ONE 5-BROMO-2-BENZOXAZOLINONE 97 LACMOID 2-Bromo-5-methoxyaniline, HCl 4-BROMO-2-METHOXYANILINE[2-AMINO-5-BROMOANISOLE] ,4-BROMO-2-METHOXYANILINE 2-BROMO-4-METHOXYANILINE 4-BROMO-3-METHOXYANILINE, 98+%,2-bromo-5-aminoanisole(4-bromo-3-methoxyaniline),4-Bromo-3-methoxyaniline, 97+%,4-BROMO-3-METHOXYANILINE 5-Bromo-2-methoxyaniline, HCl 2-BROMO-5-METHOXYANILINE 4-Bromoanisole 5,5'-DIBROMO BAPTA AM NS-2028 LABOTEST-BB LT01143471 2-BROMO-4-METHOXYANILINE Hydrochloride 3-Bromo-4-methoxyaniline hydrochloride 2-BROMO-6-METHOXYANILINE

  • 5-BROMO-2-METHOXYANILINE
  • 5-bromo-2-methoxybenzenamine
  • 2-amino-4-bromoanisole
  • 5-bromo-o-anisidine
  • 5-Bromo-2-methoxyaniline 98%
  • 2-Amino-4-bromoanisole, 5-Bromo-o-anisidine
  • 2-Methoxy-5-bromoaniline
  • 4-Bromo-2-aminoanisole
  • 5-Bromo-2-methoxyaniline &gt
  • Benzenamine, 5-bromo-2-methoxy-
  • 5-Bromo-2-methoxyaniline, 97%
  • 6358-77-6
  • Amines
  • blocks
  • Bromides