(2-FLUOROBENZYL)METHYLAMINE

Product Name: (2-FLUOROBENZYL)METHYLAMINE
CAS No.: 399-30-4
Chemical Name: (2-FLUOROBENZYL)METHYLAMINE
Synonyms: (2-FLUOROBENZYL)METH;(2-FLUOROBENZYL)METHYLAMINE;N-Methyl-2-fluorobenzylaMine;2-FLUORO-N-METHYLBENZYLAMINE;(2-fluorobenZzyl)methylamine;N-Methyl-o-fluorobenzylamine;(2-Fluorobenzyl)Methyla E 95%;(2-Fluorobenzyl)methylamine95%;(2-FLUOROBENZYL)METHYLAMINE 95%;(2-Fluorobenzyl)Methylamine,>98%
CBNumber: CB8473549
Molecular Formula: C8H10FN
Formula Weight: 139.17
MOL File: 399-30-4.mol

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(2-FLUOROBENZYL)METHYLAMINE Property

Melting point:: 139-140 °C
Boiling point:: 73 °C/12 mmHg (lit.)
Density: 1.047 g/mL at 25 °C (lit.)
refractive index: n20/D 1.5010(lit.)
Flash point:: 155 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 9.05±0.10(Predicted)
form: Liquid
color: Colorless to tan
Water Solubility: Slightly soluble in water.
Sensitive: Air Sensitive

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26-36/37
WGK Germany: 3
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 631094
Product name: 2-Fluoro-N-methylbenzylamine
Purity: 97%
Packaging: 1g
Price: $65.1
Updated: 2023/06/20

Sigma-Aldrich

Product number: 631094
Product name: 2-Fluoro-N-methylbenzylamine
Purity: 97%
Packaging: 5g
Price: $162
Updated: 2022/05/15

TRC

Product number: F596735
Product name: (2-Fluorobenzyl)methylamine
Packaging: 1g
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: PC201248
Product name: (2-Fluorobenzyl)methylamine
Purity: 98%
Packaging: 10g
Price: $103
Updated: 2021/12/16

Apolloscientific

Product number: PC201248
Product name: (2-Fluorobenzyl)methylamine
Purity: 98%
Packaging: 25g
Price: $206
Updated: 2021/12/16

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(2-FLUOROBENZYL)METHYLAMINE Chemical Properties,Usage,Production

Uses

It is used as a pharmaceutical intermediate.

Uses

Reactant for:

Preparation of biologically and pharmacologically active molecules

Synthesis

1159505-77-7

399-30-4

Example 4 Synthesis of N-methyl-2-fluorobenzylamine: to a stirred solution of compound 16 (135.6 mg, 0.5 mmol, 1.0 eq.) in anhydrous THF (5 mL) was slowly added LiAlH4 (38 mg, 1.0 mmol, 2.0 eq.) at 0 °C. The reaction mixture was heated to reflux and stirred for 10 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was carefully quenched with water and subsequently extracted with ether (10 mL x 3). The target product N-methyl-2-fluorobenzylamine was isolated and purified by acid/base extraction using 2N HCl and 2N NaOH. Finally, the solvent was evaporated under reduced pressure (15 torr) to give the colorless oily product N-methyl-2-fluorobenzylamine (60 mg, 86% yield).

References

[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7520 - 7521
[3] Patent: US2012/59179, 2012, A1. Location in patent: Page/Page column 17

(2-FLUOROBENZYL)METHYLAMINE Preparation Products And Raw materials

Raw materials

Methylamine Hydrogen bromide Phosphorus tribromide 2-Fluorobenzyl alcohol

Preparation Products

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(2-FLUOROBENZYL)METHYLAMINE Suppliers

China 96 Germany 1 India 3 Switzerland 1 United Kingdom 1 United States 11 Global 113

Creasyn Finechem(Tianjin) Co., Ltd.

Tel: 022-83946278 13820503911
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Alfa Aesar

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Energy Chemical

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Shanghai Hanhong Scientific Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

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Syntechem Co.,Ltd

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Shenyang Yuancheng Pharmaceutical Technology Co., Ltd.

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Shanghai Litong Chemical Technology Co.,Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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View Lastest Price from (2-FLUOROBENZYL)METHYLAMINE manufacturers

Career Henan Chemical Co

Product: (2-FLUOROBENZYL)METHYLAMINE 399-30-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-11

399-30-4, (2-FLUOROBENZYL)METHYLAMINERelated Search:

2-Chloro-N-ethyl-6-fluorobenzenemethanamine 2-Fluorobenzylamine (4-FLUORO-BENZYL)-METHYL-AMINE (3-FLUOROBENZYL)METHYLAMINE,(3-Fluorobenzyl)methylamine95% Diflubenzuron 2-(2-CHLORO-6-FLUOROBENZYL)-4,5-DICHLOROPYRIDAZINE-3-(2H)-ONE 4,5-DICHLORO-2-(2-FLUOROBENZYL)PYRIDAZINE-3(2H)-ONE Flumetralin Teflubenzuron N-ETHYL-O-FLUOROBENZYLAMINE TETRAFLUOROPHTHALIMIDE N-[4-(TRIFLUOROMETHYL)PHENYL]-2-FLUOROBENZAMIDE N-FORMYL-MET-LEU-PHE-O-FLUOROBENZYLAMIDE N-(N-PROPYL)-2-CHLORO-6-FLUOROBENZYLAMINE N,N-BIS(2-CHLORO-6-FLUOROBENZYL)HYDROXYLAMINE alpha-Trifluoromethyl-(3-fluorobenzyl)amine Hydrochloride N-(2-CHLORO-6-FLUOROBENZYL)-N-METHYLAMINE N1-(2,4-DIFLUOROBENZYL)-3-CHLORO-2,2-DIMETHYLPROPANAMIDE

(2-FLUOROBENZYL)METHYLAMINE

2-FLUORO-N-METHYLBENZYLAMINE

(2-Fluorobenzyl)methylamine95%

(2-FLUOROBENZYL)METHYLAMINE 95%

(2-fluorobenZzyl)methylamine

(2-Fluorobenzyl)Methyla E 95%

(2-FLUOROBENZYL)METH

N-Methyl-o-fluorobenzylamine

1-(2-FLUOROPHENYL)-N-METHYLMETHANAMINE

N-Methyl-2-fluorobenzylaMine

Benzenemethanamine, 2-fluoro-N-methyl-

(2-Fluorobenzyl)Methylamine,>98%

2-Fluoro-<i>N</i>-methylbenzylamine

399-30-4

Building Blocks

Amines

C8

Nitrogen Compounds

Organic Building Blocks

Amines

C8

Nitrogen Compounds