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Triethylene glycol dimethacrylate

Description Application Reference
Product Name
Triethylene glycol dimethacrylate
CAS No.
109-16-0
Chemical Name
Triethylene glycol dimethacrylate
Synonyms
TEGDMA;TEDMA;Ethy;TRGDMA;tgm3;tgm35;tgm3s;TGM 3;TGM 35;tgm3pc
CBNumber
CB8485829
Molecular Formula
C14H22O6
Formula Weight
286.32
MOL File
109-16-0.mol
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Triethylene glycol dimethacrylate Property

Melting point:
-52°C
Boiling point:
170-172 °C5 mm Hg(lit.)
Density 
1.092 g/mL at 25 °C(lit.)
vapor pressure 
0.077Pa at 20℃
refractive index 
n20/D 1.461(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform, Methanol
form 
Oil
color 
Colourless to Pale Yellow
Specific Gravity
1.092
Water Solubility 
3.6g/L at 20℃
BRN 
1797351
Stability:
Light Sensitive
InChIKey
HWSSEYVMGDIFMH-UHFFFAOYSA-N
LogP
2.3 at 20℃
CAS DataBase Reference
109-16-0(CAS DataBase Reference)
NIST Chemistry Reference
2-Propenoic acid, 2-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester(109-16-0)
EPA Substance Registry System
Triethylene glycol dimethacrylate (109-16-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-43
Safety Statements 
26-28-36/37
RIDADR 
UN 3334
WGK Germany 
1
RTECS 
OZ4100000
8-19
TSCA 
TSCA listed
HS Code 
29161900
Hazardous Substances Data
109-16-0(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 10837mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
261548
Product name
Triethylene glycol dimethacrylate
Purity
contains 80-120 ppm MEHQ as inhibitor, 95%
Packaging
250ml
Price
$82.2
Updated
2024/03/01
Sigma-Aldrich
Product number
261548
Product name
Triethylene glycol dimethacrylate
Purity
contains 80-120 ppm MEHQ as inhibitor, 95%
Packaging
1l
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
759406
Product name
Triethylene glycol dimethacrylate
Purity
contains 200?ppm monomethyl ether hydroquinone as inhibitor, 99%
Packaging
1ML
Price
$361
Updated
2023/06/20
TCI Chemical
Product number
T0948
Product name
Triethylene Glycol Dimethacrylate (stabilized with MEHQ)
Purity
>95.0%(GC)
Packaging
25mL
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
T0948
Product name
Triethylene Glycol Dimethacrylate (stabilized with MEHQ)
Purity
>95.0%(GC)
Packaging
500mL
Price
$89
Updated
2024/03/01
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Triethylene glycol dimethacrylate Chemical Properties,Usage,Production

Description

Triethylene glycol dimethacrylate is used as a cross-linking agent in the synthesis of poly (methacrylic acid-g-ethylene glycol) hydrogels which shows large changes in swelling due to changes in pH, temperature and solvent composition. They are also used as divinylic methacrylic monomers which are widely used to form copolymers with divinylbenzene (DVB) and glycidyl methacrylate (GMA) or hydroxyethyl methacrylate (HEMA) comonomers. As a monomer, it is typically used in dental resin materials that can cause specific stress responses in eukaryotic cells. It commonly used to aesthetically restore the structure and function of teeth impaired by caries, erosion, or fracture.
It is cytotoxic via apoptosis, induce genotoxic effects, and delay the cell cycle. It also influences the response of cells of the innate immune system, inhibit specific odontoblast cell functions, or delay the odontogenic differentiation and mineralization processes in pulp-derived cells including stem cells. It is also used as a diluent co-monomer in dimethacrylate based dental composites as well as being used as a branching agent in the atom transfer radical polymerization (ATRP) of styrene.

Application

Triethylene glycol dimethacrylate (TEGDMA) is a resin monomer widely used in the composition of dentin bonding agents and composite resins to restore teeth structures impaired by caries and/or fractures. However, resin monomers can be released into the oral environment and can trigger hazardous biological effects on oral tissues. The release of the resin monomers due to degradation and incomplete polymerization can occur hours or days after the treatment. Due to its hydrophilic nature, hydrolysis plays an important role in the degradation processe of TEGDMA. Chemical interactions with oral fluids and mechanical influences may also cause the degradation of resin monomers. Direct contact or diffusion of resin monomers through the dentinal tubules creates ways of interaction between dental pulp tissue and resin monomers. Dentin thickness and the severity of caries lesions are important factors in determining the amount of resin monomers interacting with dental pulp tissue. TEGDMA has been reported to cause cytotoxicity, impaired cellular functions, pulpal inflammatory responses, and changes in the immune system. In addition, TEGDMA may reduce the mineralization capacity of dental pulp cells by decreasing the expression of the mineralization related genes pathways and causing adverse effects.

Reference

Krifka, S, et al. "A review of adaptive mechanisms in cell responses towards oxidative stress caused by dental resin monomers. " Biomaterials 34.19(2013):4555-4563.

Description

Triethylene glycol dimethacrylate was employed to optimize the dilution of high-viscosity monomers and to link together the macromolecules constituting the polymer, to make their three-dimentional structure more rigid. It is also a crosslinking agent of acrylic resins, used in sealents or in dental bonding resins. These are mainly used in dentistry, by dental technicians and dentists.

Chemical Properties

Colorless liquid

Uses

Triethyleneglycol dimethacrylate is a methacrylic monomer for use as cross-linking agent for adhesives and dental restorative materials.

Uses

TEGDMA is a monomer typically used in dental resin materials that can cause specific stress responses in eukaryotic cells.

Uses

Esters of acrylic acid and methacrylic acid, more commonly known as acrylates and methacrylates are key raw materials in the coatings and printing industry, and in food packaging.

General Description

Triethylene glycol dimethacrylate (TEGDMA) is a hydrophilic, low viscosity, difunctional methacrylic monomer employed as a crosslinking agent.

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Triethylene glycol dimethacrylate Suppliers

KPX Green Chemical Co., Ltd.
Tel
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Fax
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Email
kdh@korgc.com
Country
South Korea
ProdList
28
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58
Hannong Chemicals Inc.
Tel
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Fax
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Email
ir@hannong.co.kr
Country
South Korea
ProdList
40
Advantage
58
Miwon Specialty Chemical Co., Ltd.
Tel
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Fax
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Email
miramer@mwc.co.kr
Country
South Korea
ProdList
16
Advantage
58
Miwon Commercial Co., Ltd.
Tel
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Fax
--
Email
pcbu@mwc.co.kr
Country
South Korea
ProdList
226
Advantage
46
CHEMICAL LAND21
Tel
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Fax
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Email
sales21@chemicalland21.com
Country
South Korea
ProdList
6303
Advantage
74
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View Lastest Price from Triethylene glycol dimethacrylate manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Triethylene glycol dimethacrylate 109-16-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Triethylene glycol dimethacrylate 109-16-0
Price
US $0.00/KG
Min. Order
25KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-30
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Triethylene glycol dimethacrylate 109-16-0
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-29

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