ChemicalBook > CAS DataBase List > 4-Hydroxy-2-butanone

4-Hydroxy-2-butanone

Product Name
4-Hydroxy-2-butanone
CAS No.
590-90-9
Chemical Name
4-Hydroxy-2-butanone
Synonyms
4-hydroxybutan-2-one;CH3C(O)CH2CH2OH;Methylolacetone;2-Butanone, 4-hydroxy-;3-Oxobutanol;Butanone glycol;3-Ketobutan-1-ol;H**4-HYDROXY-2-BUTANONE;ketobutanol;3-Oxo-1-butanol
CBNumber
CB8493505
Molecular Formula
C4H8O2
Formula Weight
88.11
MOL File
590-90-9.mol
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4-Hydroxy-2-butanone Property

Melting point:
15°C (estimate)
Boiling point:
73-76 °C/12 mmHg (lit.)
Density 
1.023 g/mL at 25 °C (lit.)
refractive index 
1.430
Flash point:
91°F
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform, Methanol (Slightly)
form 
Oil
pka
14.43±0.10(Predicted)
color 
Clear Colourless
Water Solubility 
Miscible with water, alcohol, ethanol and ether.
BRN 
1737666
LogP
-1.209 at 25℃
CAS DataBase Reference
590-90-9(CAS DataBase Reference)
NIST Chemistry Reference
4-Hydroxy-2-butanone(590-90-9)
EPA Substance Registry System
2-Butanone, 4-hydroxy- (590-90-9)
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Safety

Risk Statements 
10
Safety Statements 
16-24/25
RIDADR 
UN 1993
WGK Germany 
3
TSCA 
Yes
HS Code 
29144000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
252557
Product name
4-Hydroxy-2-butanone
Purity
95%
Packaging
100g
Price
$176
Updated
2024/03/01
TCI Chemical
Product number
H0584
Product name
4-Hydroxy-2-butanone
Purity
>95.0%(GC)
Packaging
25mL
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
H0584
Product name
4-Hydroxy-2-butanone
Purity
>95.0%(GC)
Packaging
100mL
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
L11456
Product name
4-Hydroxy-2-butanone, 95%
Packaging
25g
Price
$59.1
Updated
2024/03/01
Alfa Aesar
Product number
L11456
Product name
4-Hydroxy-2-butanone, 95%
Packaging
100g
Price
$150
Updated
2024/03/01
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4-Hydroxy-2-butanone Chemical Properties,Usage,Production

Chemical Properties

Colourless to pale yellow liquid

Uses

4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.

Application

4-Hydroxy-2-butanone has been used in the synthesis of:

  • 3-buten-2-one via dehydration over anatase-TiO2 catalyst
  • 4-methyl-5-hydroxymethylthiazole
  • (±)-lineatin
  • mevalonic acid lactone
  • verrucarin
  • β-hydroxylactones

Definition

ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.

General Description

4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.

4-Hydroxy-2-butanone Preparation Products And Raw materials

Raw materials

Acetone Vitamin A Formaldehyde Potassium carbonate Paraformaldehyde Hydrochloric acid Methyl vinyl ketone

Preparation Products

Methyl vinyl ketone
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4-Hydroxy-2-butanone Suppliers

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View Lastest Price from 4-Hydroxy-2-butanone manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
4-Hydroxy-2-butanone 590-90-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-11-16
Hebei Yanxi Chemical Co., Ltd.
Product
4-Hydroxy-2-butanone 590-90-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
95%+
Supply Ability
30MT/Month
Release date
2023-01-30
Hebei Weibang Biotechnology Co., Ltd
Product
4-Hydroxy-2-butanone 590-90-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25

590-90-9, 4-Hydroxy-2-butanoneRelated Search:

Methylparaben Kresoxim-methyl CHLOROPHOSPHONAZO III Bensulfuron methyl 4-Cyanophenol 2-Butanone oxime Methyl acrylate 2-(METHYLSULFONYL)ETHANOL 4-Methyl-2-pentanone Methyl Parathion-methyl Acetoin 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Methyl 4-chloro-3-oxo-butanoate Ethyl 4,4,4-trifluoroacetoacetate Ethyl 2-oxocyclopentanecarboxylate Ethyl 2-oxocyclohexanecarboxylate Mordant Blue 29

  • H**4-HYDROXY-2-BUTANONE
  • 2-Butanone, 4-hydroxy-
  • 2-Butanone,4-hydroxy-
  • 3-Ketobutan-1-ol
  • 3-Oxo-1-butanol
  • 3-Oxobutanol
  • 4-Butanol-2-one
  • 4-hydroxy-2-butanon
  • CH3C(O)CH2CH2OH
  • Methylolacetone
  • Monomethylolacetone
  • 4-HYDROXY-2-BUTANONE
  • 2-HYDROXYETHYL METHYL KETONE
  • 4-hydroxybutan-2-one
  • 4-Hydroxy-2-butanone,95%
  • ketobutanol
  • 1-Hydroxy-3-butanone
  • Hydroxy-2-butan
  • 4-Hydroxy-2-butanone , 95.0%(GC)
  • 4-hydrxy-2-butone
  • Butanone glycol
  • 4-Hydroxy-2-butanone &gt
  • 590-90-9
  • 590-50-9
  • HOCH2CH2COCH3
  • KETONE
  • Organic Building Blocks
  • Ketones
  • Carbonyl Compounds
  • C3 to C6
  • Building Blocks
  • in-stock
  • straight chain compounds
  • ketone
  • 1
  • bc0001
  • 590-90-9
  • john's