NU7026

Product Name: NU7026
CAS No.: 154447-35-5
Chemical Name: NU7026
Synonyms: CS-595;LY 293646;NU7026, >=98%;NU 7026; NU-7026;NU7026 USP/EP/BP;NU7026;LY293646; NU-7026;NU 7026, DNA-PK inhibitor;DNA-PK Inhibitor II NU7026 NU-7026;2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one
CBNumber: CB8503981
Molecular Formula: C17H15NO3
Formula Weight: 281.31
MOL File: 154447-35-5.mol

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NU7026 Property

Melting point:: 267-269 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:: 459.9±45.0 °C(Predicted)
Density: 1.330
storage temp.: 2-8°C
solubility: DMSO: 3 mg/mL at 60 °C, soluble
form: solid
pka: 0.49±0.20(Predicted)
color: tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N1537
Product name: NU7026
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $279
Updated: 2024/03/01

Sigma-Aldrich

Product number: 260961
Product name: DNA-PK Inhibitor II
Packaging: 5mg
Price: $245
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 25mg
Price: $356
Updated: 2024/03/01

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NU7026 Chemical Properties,Usage,Production

Uses

DNA-PK Inhibitor II is an antiproliferative agent, and inhibitor of DNA-PK.

Uses

NU7026 has been used:

as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell
in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)
to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells

Definition

ChEBI: 2-(4-morpholinyl)-4-benzo[h][1]benzopyranone is an organooxygen compound and an organic heterotricyclic compound.

Biological Activity

ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair.

Biochem/physiol Actions

Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).

storage

Store at +4°C

NU7026 Preparation Products And Raw materials

Raw materials

Preparation Products

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NU7026 Suppliers

China 85 India 1 Switzerland 1 United Kingdom 2 United States 15 Global 104

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9958
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Chengdu YouSuo Biotechnology Limited

Tel: 13693449011
Fax: -
Email: 83948782@qq.com
Country: China
ProdList: 92
Advantage: 50

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View Lastest Price from NU7026 manufacturers

Career Henan Chemical Co

Product: NU7026 154447-35-5
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-24

154447-35-5, NU7026Related Search:

Imidazolidinyl urea NU7441 (KU-57788) KU-55933 (ATM Kinase Inhibitor) VE-821 KU-60019 ABT 737 Olaparib NU7026 4H-1-Benzopyran-4-one, 2-(diethylamino)-

DNA-PK Inhibitor II - CAS 154447-35-5 - Calbiochem

NU 7026; NU-7026

CS-595

2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE

NU7026, >=98%

2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one

NU7026;LY293646; NU-7026

LY 293646

2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one

4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)-

2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026

NU7026 USP/EP/BP

DNA-PK Inhibitor II NU7026 NU-7026

DNA-dependent protein kinase,inhibit,NU-7026,Apoptosis,DNA-PK,LY-293646,Inhibitor,LY 293646,NU 7026

NU 7026, DNA-PK inhibitor

154447-35-5

Inhibitors