6-Methyl-2-(methylthio)pyrimidin-4-ol
- Product Name
- 6-Methyl-2-(methylthio)pyrimidin-4-ol
- CAS No.
- 6328-58-1
- Chemical Name
- 6-Methyl-2-(methylthio)pyrimidin-4-ol
- Synonyms
- NSC37678;NSC43815;ST074533;NSC193525;ST5114026;ZINC05182359;ZINC00039515;ZINC03864720;Enamine_001117;6-Methyl-2-(methylthio)
- CBNumber
- CB8663120
- Molecular Formula
- C6H8N2OS
- Formula Weight
- 156.21
- MOL File
- 6328-58-1.mol
6-Methyl-2-(methylthio)pyrimidin-4-ol Property
- Melting point:
- 224-226°C
- Boiling point:
- 259.2±23.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- solid
- pka
- 8.24±0.50(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39-24/25
- WGK Germany
- 3
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- R683868
- Product name
- 6-METHYL-2-(METHYLTHIO)-4(3H)-PYRIMIDINONE
- Purity
- AldrichCPR
- Packaging
- 10MG
- Price
- $148
- Updated
- 2025/07/31
- Product number
- 775754
- Product name
- 4-Hydroxy-6-methyl-2-methylthiopyrimidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $268
- Updated
- 2023/06/20
- Product number
- M338678
- Product name
- 6-Methyl-2-(methylthio)-1H-pyrimidin-4-one
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR939412
- Product name
- 6-Methyl-2-(methylthio)-1H-pyrimidin-4-one
- Purity
- 95%
- Packaging
- 10g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- Z2590
- Product name
- 2-Methylmercapto-4-hydroxy-6-methylpyrimidine
- Packaging
- 10g
- Price
- $141
- Updated
- 2021/12/16
6-Methyl-2-(methylthio)pyrimidin-4-ol Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
56-04-2
74-88-4
6328-58-1
Sodium hydroxide (97%, 15.7 g, 381 mmol) was added to 500 mL of water and the suspension was stirred for 10 min at room temperature. 6-Methyl-2-thioxasulfinyl-1,2,3,4-tetrahydropyrimidin-4-one (98%, 53.5 g, 369 mmol) was added and the mixture was stirred until completely dissolved for 10 minutes. Iodomethane (28.99 mL, 461 mmol) was slowly added dropwise and the reaction mixture continued to be stirred for 4 hours at room temperature. After completion of the reaction, a colorless solid was obtained by filtration, washed with ice-cold water (2 x 100 mL) and dried under vacuum at 60 °C to give 6-methyl-4-hydroxy-2-methylthiopyrimidine (57 g, 98% yield) as a colorless solid. The product was analyzed by LC-MS: m/z = 156.9 [M + H]+; retention time (RT) = 0.61 min.
References
[1] Patent: WO2017/59191, 2017, A1. Location in patent: Paragraph 00126-00129
[2] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 18, p. 3025 - 3030
[3] Archiv der Pharmazie, 1984, vol. 317, # 5, p. 425 - 430
6-Methyl-2-(methylthio)pyrimidin-4-ol Preparation Products And Raw materials
Raw materials
Preparation Products
6-Methyl-2-(methylthio)pyrimidin-4-ol Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 6-Methyl-2-(methylthio)pyrimidin-4-ol manufacturers
- Product
- 6-METHYL-2-(METHYLTHIO)PYRIMIDIN-4-OL
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-08