ChemicalBook > CAS DataBase List > Linarin

Linarin

Product Name
Linarin
CAS No.
480-36-4
Chemical Name
Linarin
Synonyms
BUDDLEOSIDE;ACACETIN-7-O-RUTINOSIDE;BUDDLOSIDE;Buddleoflavonoloside;Linarigenin glycoside;Acacetin-7-O-β-D-rutinoside;LINARIN;Linarine;Linarin-RM;Linaric acid
CBNumber
CB8663711
Molecular Formula
C28H32O14
Formula Weight
592.55
MOL File
480-36-4.mol
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Linarin Property

Melting point:
258-260°C
Boiling point:
885.2±65.0 °C(Predicted)
Density 
1.62±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Acetic Acid (Very Slightly, Heated), Acetonitrile (Slightly), DMSO (Slightly)
form 
Solid
pka
6.11±0.40(Predicted)
color 
White to Pale Beige
Stability:
Hygroscopic
InChIKey
YFVGIJBUXMQFOF-BWLJPJRBNA-N
SMILES
C12C(O)=CC(O[C@H]3[C@H](O)[C@H]([C@H](O)[C@@H](CO[C@@H]4O[C@H]([C@H](O)[C@@H](O)[C@H]4O)C)O3)O)=CC=1OC(C1C=CC(OC)=CC=1)=CC2=O |&1:6,7,9,10,12,15,17,18,20,22,r|
CAS DataBase Reference
480-36-4(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80822
Product name
Linarin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$304
Updated
2025/07/31
TCI Chemical
Product number
L0447
Product name
Linarin
Packaging
250MG
Price
$345
Updated
2025/07/31
Cayman Chemical
Product number
26900
Product name
Linarin
Packaging
5mg
Price
$66
Updated
2024/03/01
Cayman Chemical
Product number
26900
Product name
Linarin
Packaging
10mg
Price
$111
Updated
2024/03/01
Cayman Chemical
Product number
26900
Product name
Linarin
Packaging
25mg
Price
$242
Updated
2024/03/01
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Linarin Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, easily soluble in methanol, almost insoluble in ether, derived from wild chrysanthemum, great thistle, and small thistle.

Uses

Linarine (Diosmin EP Impurity E) is a naturally occurring flavone glycoside that was identified to possess potential sedative and anticonvulsant properties.

in vivo

Linarin (oral administration; 50-150 mg/kg; 8 weeks) can improve bone loss in ovariectomized mice[2].

Animal Model:Ovariectomy treated female C57/BL6 mice[2]
Dosage:50 and 150 mg/kg
Administration:Oral administration (p.o.); 8 weeks
Result:Dose?dependently preserved the trabecular bone microarchitecture of ovariectomized mice.
Slightly increased BMD compared to the control OVX group.
Significantly decreased OVX-induced serum ALP and OCN levels.

IC 50

AChE

Linarin Preparation Products And Raw materials

Raw materials

Preparation Products

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Linarin Suppliers

EMMX Biotechnology LLC
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View Lastest Price from Linarin manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Linarin Powder 480-36-4
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-14
Shaanxi Dideu Medichem Co. Ltd
Product
Linarin 480-36-4
Price
US $1.00-2.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
20000KG
Release date
2024-08-09
Hebei Fengqiang Trading Co., LTD
Product
Linarin 480-36-4
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-08-31

480-36-4, LinarinRelated Search:


  • LINARIN
  • BUDDLEOSIDE
  • BUDDLOSIDE
  • ACACETIN-7-O-RUTINOSIDE
  • ACACETIN-7-RUTINOSIDE
  • 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-4'-methoxyflavone
  • 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
  • 7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
  • Acacetin-7-O-β-D-rutinoside
  • Buddleoflavonoloside
  • Linarigenin glycoside
  • Buddleoside,Linarin
  • 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
  • Buddloside,Linarin
  • LINARIN WITH HPLC
  • ACACETIN-7-RUTINOSIDE hplc
  • Linarine
  • Diosmin Impurity E (Linarin)
  • 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-4'-methoxyflavone
  • 2-(4-methoxyphenyl)-4H-benzopyran-4-one
  • 7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-
  • Flos Chrysanthemi Indici Extract
  • Linarin, 98%, from Dendranthema indicum (L.) Des Moul.
  • Acaciin、Buddleoside
  • Diosmin Impurity 5 (Diosmin EP Impurity E)(Linarin)
  • Buddleoside 480-36-4
  • Diosmin EP Impurity E(Linarin)
  • Extract of Chrysanthemum indicum
  • Diosmin ep imp E
  • Diosmin EP Impurity E
  • 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-
  • 5-hydroxy-2-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
  • Linarine (1.0 mg/mL in Methanol)
  • 5-Hydroxy-2-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
  • Linaric acid
  • 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranos...
  • Diosmin EP Impurity EQ: What is Diosmin EP Impurity E Q: What is the CAS Number of Diosmin EP Impurity E Q: What is the storage condition of Diosmin EP Impurity E Q: What are the applications of Diosmin EP Impurity E
  • Linarin 480-36-4
  • 5-Hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside
  • Linarin (6CI, 7CI, 8CI)
  • 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one (linarin),
  • Linarin (50 mg)
  • Linarin Powder
  • Linarin-RM
  • Dioxamine EP Impurity E
  • Linarin, 10 mM in DMSO
  • 480-36-4
  • C28H33O14
  • 59255
  • Tri-substituted Flavones
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract