ChemicalBook > CAS DataBase List > N-Ethylmorpholine

N-Ethylmorpholine

Product Name
N-Ethylmorpholine
CAS No.
100-74-3
Chemical Name
N-Ethylmorpholine
Synonyms
HEM;Ethylmorpholine;4-ETHYLMORPHOLINE;N-Ethylmorfolin;Texacat NEM;Toyocat -NEM;LUPRAGEN(R) N 104;N-ETHYLMORPHOLINE;4-ethyl-morpholin;4-Ethylmorhpoline
CBNumber
CB8667476
Molecular Formula
C6H13NO
Formula Weight
115.17
MOL File
100-74-3.mol
More
Less

N-Ethylmorpholine Property

Melting point:
-63 °C (lit.)
Boiling point:
139 °C (lit.)
Density 
0.91 g/mL at 20 °C (lit.)
vapor pressure 
8.1 hPa (20 °C)
refractive index 
n20/D 1.441(lit.)
Flash point:
82 °F
storage temp. 
Store below +30°C.
solubility 
miscible
form 
Powder
pka
7.67(at 25℃)
color 
Cream to beige to brown-grey
PH
11.8 (100g/l, H2O, 20℃)
explosive limit
1.9%(V)
Water Solubility 
miscible
FreezingPoint 
-63℃
Sensitive 
Air Sensitive
BRN 
102969
Exposure limits
NIOSH REL: TWA 5 ppm (23 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 20 ppm (94 mg/m3); ACGIH TLV: TWA 5 ppm (adopted).
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents. Slightly air sensitive.
LogP
0.08 at 24.6℃
CAS DataBase Reference
100-74-3(CAS DataBase Reference)
NIST Chemistry Reference
Morpholine, 4-ethyl-(100-74-3)
EPA Substance Registry System
N-Ethylmorpholine (100-74-3)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
10-21/22-34
Safety Statements 
26-36/37/39-45-16
RIDADR 
UN 2920 8/PG 2
OEB
A
OEL
TWA: 5 ppm (23 mg/m3) [skin]
WGK Germany 
1
RTECS 
QE4025000
F 
8-23
Autoignition Temperature
160 °C
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29349990
Hazardous Substances Data
100-74-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1640 mg/kg LD50 dermal Rabbit 900 mg/kg
IDLA
100 ppm
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
04499
Product name
4-Ethylmorpholine
Purity
BioXtra, suitable for protein sequencing, ≥99.5% (GC)
Packaging
25ml
Price
$94.7
Updated
2024/03/01
Sigma-Aldrich
Product number
04499
Product name
4-Ethylmorpholine
Purity
BioXtra, suitable for protein sequencing, ≥99.5% (GC)
Packaging
100ml
Price
$266
Updated
2024/03/01
Sigma-Aldrich
Product number
8.01295
Product name
4-Ethylmorpholine
Purity
for synthesis
Packaging
250ML
Price
$35.4
Updated
2022/05/15
TCI Chemical
Product number
E0145
Product name
4-Ethylmorpholine
Purity
>99.0%(GC)(T)
Packaging
25mL
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
E0145
Product name
4-Ethylmorpholine
Purity
>99.0%(GC)(T)
Packaging
500mL
Price
$47
Updated
2024/03/01
More
Less

N-Ethylmorpholine Chemical Properties,Usage,Production

Chemical Properties

4-Ethylmorpholine is a colorless liquid with an ammonia-like odor.

Physical properties

Colorless, flammable liquid with an ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 400 μg/m3 (85 ppbv) and 1.2 mg/m3 (250 ppbv), respectively (Hellman and Small, 1974).

Uses

Catalyst in polyurethane foam production

Uses

N-Ethylmorpholine is a component of the buffer used in basic peptide separation through anion-exchange chromatography. Further, it acts as a catalyst in the preparation of polyurethane foam.

Uses

Intermediate for dyestuffs, pharmaceuticals; rubber accelerators and emulsifying agents; solvent for dyes, resins, oils; catalyst in making polyurethane foams.

Preparation

N-Ethylmorpholine is synthesized by the reaction of morpholine with bromoethane.

Synthesis Reference(s)

The Journal of Organic Chemistry, 56, p. 678, 1991 DOI: 10.1021/jo00002a035
Tetrahedron Letters, 37, p. 6749, 1996 DOI: 10.1016/S0040-4039(96)01458-X

General Description

N-Ethylmorpholine appears as a colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83°F.

Air & Water Reactions

Highly flammable. Moderately soluble in water .

Reactivity Profile

N-Ethylmorpholine can react vigorously with oxidizing materials. N-Ethylmorpholine dissolves LiAlH4.

Hazard

Irritant to skin and eyes, absorbed by skin. Flammable, moderate fire risk. Toxic by skin absorption.

Health Hazard

Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights.

Flammability and Explosibility

Flammable

Safety Profile

oison by intravenous route. Moderately toxic by ingestion. Mildly toxic by inhalation. A skin and severe eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidzing materials. To fight fire, use alcohol foam, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

Primary irritant (without allergic reaction). This material is used as a catalyst in polyurethane foam production. It is a solvent for dyes and resins. It is used as an intermediate in surfactant, dye, pharmaceutical, and rubber chemical manufacture

Environmental Fate

Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987).
At an influent concentration of 1,000 mg/L, treatment with GAC resulted in an effluent concentration of 467 mg/L. The adsorbability of the carbon used was 107 mg/g carbon (Guisti et al., 1974).

Shipping

UN2920 Corrosive liquids, flammable, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable liquid. UN1993 Flammable liquids, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required

Incompatibilities

May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine,etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Corrodes some metals. Unless inhibited, violent polymerization can occur from heat, sunlight, and contact with strong oxidizers permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Attacks some plastics, rubber and coatings

Waste Disposal

Controlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices).

N-Ethylmorpholine Preparation Products And Raw materials

Raw materials

Diethylene glycol Bromoethane Ammonia

Preparation Products

Water quality stabilizer Trandolapril
More
Less

N-Ethylmorpholine Suppliers

Americas 1 Belgium 1 Canada 1 China 170 Europe 4 France 1 Germany 10 India 19 Italy 1 Japan 6 Malaysia 1 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 12 United States 32 Global 263
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
MD Chemicals
Tel
--
Fax
--
Email
info@mdchemicals.net
Country
United States
ProdList
158
Advantage
58
Huntsman Corporation
Tel
--
Fax
--
Email
hpporders@huntsman.com
Country
United States
ProdList
28
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
CiVentiChem Inc.
Tel
--
Fax
--
Email
sales@cvchem.com
Country
United States
ProdList
50
Advantage
50
Amines & Plasticizers
Tel
--
Fax
--
Email
marketing@amines.com
Country
United States
ProdList
28
Advantage
63
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
SKC Inc.
Tel
--
Fax
--
Email
skcorder@skcinc.com
Country
United States
ProdList
1378
Advantage
76
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Loba Chemie Pvt. Ltd.
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
71
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Acros Organics USA
Tel
--
Fax
--
Email
eveleth@fisherchem.com
Country
United States
ProdList
3846
Advantage
81
BASF Corporation
Tel
--
Fax
--
Country
United States
ProdList
573
Advantage
86
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
More
Less

View Lastest Price from N-Ethylmorpholine manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
N-Ethylmorpholine 100-74-3
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-05
Hebei Weibang Biotechnology Co., Ltd
Product
4-Ethylmorpholine 100-74-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2021-01-20
Career Henan Chemical Co
Product
N-Ethylmorpholine 100-74-3
Price
US $1.00/kg
Min. Order
1kg
Purity
As required
Supply Ability
1000kg
Release date
2018-12-20

100-74-3, N-EthylmorpholineRelated Search:

Dimethomorph Moroxydine Tridemorph Moroxydine hydrochloride N-Formylmorpholine 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)THIOUREA 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE MOPS 2-Morpholinoethanol 3-MORPHOLINO-1,2-PROPANEDIOL 4-[2-(PIPERAZIN-1-YL)-ACETYL]-MORPHOLINE 4-DIMETHYLAMINE ETHYLMORPHOLINE N-(1-Cyclopenten-1-yl)morpholine 3-(4-MORPHOLINO)PROPIONITRILE N-Acetylmorpholine MOPSO N-(1-Cyclohexen-1-yl)morpholine Morniflumate

  • 4-ethyl-morpholin
  • Texacat NEM
  • Toyocat -NEM
  • N-ETHYLMORPHOLINE
  • LUPRAGEN(R) N 104
  • 4-ETHYLMORPHOLINE
  • 4-ETHYLMORPHOLINE, FOR PROTEIN SEQUENCE ANALYSIS
  • N-ETHYLMORPHOLINE 99%
  • N-Ethyl-MorpholineForSynthesis
  • 4-Ethylmorhpoline
  • Morpholine, 4-ethyl-
  • Dabco NCM, NEM, NMM
  • Ethylmorpholine
  • HEM
  • n-ethvlmorpholine
  • N-Ethyldiethylenimideoxide
  • N-Ethylmorfolin
  • N-Ethyltetrahydro-1,4-oxazine
  • N-Ethylmorpholine,99%
  • Lupragen N104 (N Ethylmorpholine)
  • N-EthylMorpholine, 99% 100ML
  • N-EthylMorpholine, 99% 500ML
  • 4-ETHYLMORPHOLINE FOR SYNTHESIS
  • N-EthylMorpholine, 98.5%
  • 4-Ethylmorpholine,98%
  • 4-EthylMorpholine >=97.0% (GC)
  • 4-Ethylmorpholine, 99%, bioxtra grade
  • 4-Ethylmorpholine&gt
  • N-Ethylmorpholine cas no: 100-74-3
  • N-Ethyl-morpholine 97% For Synthesis
  • 100-74-3
  • CH3CH2NCH2CH2OCH2CH2
  • C6H13ON
  • BioChemical
  • Building Blocks
  • Morpholines
  • Heterocyclic Building Blocks
  • Protein Analysis
  • Proteomics and Protein Expression
  • Protein Sequencing
  • Reagents for Protein Sequencing
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Morpholines/Thiomorpholines
  • Heterocyclic Building Blocks
  • Morpholines
  • Isoxazoles ,Oxazoles
  • Protein Sequencing
  • Protein Structural Analysis
  • Reagents for Protein Sequencing
  • Building Blocks