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3,4-DIHYDROISOQUINOLINE

Product Name
3,4-DIHYDROISOQUINOLINE
CAS No.
3230-65-7
Chemical Name
3,4-DIHYDROISOQUINOLINE
Synonyms
AKOS 213-252;3,4-DihydroisoquinoL;4-DIHYDROISOQUINOLINE;3,4-DIHYDROISOQUINOLINE;Isoquinoline, 3,4-dihydro-;3,4-Dihydroisoquinoline ,97%;3,4-Dihydroisoquinoline >=97.5% (GC);3,4-DIHYDROISOQUINOLINE ISO 9001：2015 REACH
CBNumber
CB8674610
Molecular Formula
C9H9N
Formula Weight
131.17
MOL File
3230-65-7.mol
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3,4-DIHYDROISOQUINOLINE Property

Melting point:
251-254℃
Boiling point:
241.8±20.0℃ (760 Torr)
Density 
1.05±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.6041 (589.3 nm 30℃)
Flash point:
91.6±22.6℃
storage temp. 
2-8°C
pka
5.80±0.20(Predicted)
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Safety

Hazard Codes 
T
Risk Statements 
22-24-36/38
Safety Statements 
26-36/37-45
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H310Fatal in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
779385
Product name
3,4-Dihydroisoquinoline
Purity
≥97.5% (GC)
Packaging
1g
Price
$205
Updated
2024/03/01
Sigma-Aldrich
Product number
779385
Product name
3,4-Dihydroisoquinoline
Purity
≥97.5% (GC)
Packaging
5g
Price
$382.8
Updated
2024/03/01
TRC
Product number
D450820
Product name
3,4-Dihydroisoquinoline
Packaging
5g
Price
$1540
Updated
2021/12/16
Matrix Scientific
Product number
177535
Product name
3,4-Dihydroisoquinoline
Purity
95%
Packaging
25g
Price
$2146
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0098048
Product name
3,4-DIHYDROISOQUINOLINE
Purity
95.00%
Packaging
5MG
Price
$499.52
Updated
2021/12/16
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3,4-DIHYDROISOQUINOLINE Chemical Properties,Usage,Production

Uses

3,4-Dihydroisoquinoline is derived from 1,2,3,4-Tetrahydroisoquinoline (T293820), which is used as a reagent in the preparation of 4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.

Uses

3,4-Dihydroisoquinoline can be used as a reactant to synthesize:

  • 5,6-Dihydro-8H-isoquino[1,2-b]quinazolin-8-one by decarboxylative cyclization reaction with isatoic anhydride using tetrabutylammonium iodide (TBAI).
  • 1-naphtholyl tetrahydroisoquinoline by aza-Friedel-Crafts reaction with various naphthols.
  • 3,4-dihydroisoquinoline pseudo bases, which are employed as starting materials for the preperation of 3-benzazepine derivatives.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 6567, 1994 DOI: 10.1016/S0040-4039(00)78274-8

3,4-DIHYDROISOQUINOLINE Preparation Products And Raw materials

Raw materials

2-PhenylethylaMine Ethyl formate Formic acid Chloroform Polyphosphoric acid Sodium carbonate

Preparation Products

Praziquantel
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3,4-DIHYDROISOQUINOLINE Suppliers

China 62 Germany 1 India 1 South Korea 1 United Kingdom 3 United States 7 Global 75
CARBONE SCIENTIFIC CO.,LTD
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ETA SCIENTIFIC Co.,Ltd
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UK GREEN SCIENTIFIC CO.,LIMITED
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sales@gs-chem.com
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United Kingdom
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6098
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3230-65-7, 3,4-DIHYDROISOQUINOLINERelated Search:

7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride 1-METHYL-6,7-DIHYDROXY-3,4-DIHYDROISOQUINOLINE MONOHYDRATE 1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline 1-METHYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE, 99+% 3,4-DIHYDROISOQUINOLINE 3,4-Dihydro-2H-isoquinolin-1-one 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER 1,2-Dihydroisoquinoline-1-one 1-Phenyl-3,4-dihydroisoquinoline 2-BENZYL-2,3-DIHYDROISOQUINOLIN-4(1H)-ONE HYDROCHLORIDE 7-Amino-1,2-dihydroisoquinolin-3-(4H)-one 6-Methoxy-3(2H)-isoquinolinone TERT-BUTYL 5-HYDROXY-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 2-TERT-BUTYL 6-METHYL 3,4-DIHYDROISOQUINOLINE-2,6(1H)-DICARBOXYLATE 1-CYANO-2-BENZOYL-1,2-DIHYDROISOQUINOLINE TERT-BUTYL 6-HYDROXY-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 6,7-Dimethoxy-3,4-dihydroisoquinoline

  • 3,4-DIHYDROISOQUINOLINE
  • AKOS 213-252
  • 3,4-Dihydroisoquinoline >=97.5% (GC)
  • 3,4-Dihydroisoquinoline ,97%
  • Isoquinoline, 3,4-dihydro-
  • 3,4-DihydroisoquinoL
  • 3,4-DIHYDROISOQUINOLINE ISO 9001：2015 REACH
  • 4-DIHYDROISOQUINOLINE
  • 3230-65-7