ChemicalBook > CAS DataBase List > 1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER

1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER

Product Name
1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
CAS No.
864754-18-7
Chemical Name
1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
Synonyms
inoethyL;1-(2-MorphoL;1-(2-Morpholinoethyl)-1H<;1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid;1-(2-Morpholinoethyl)pyrazole-4-boronic Acid Pinacol Ester;1-(2-MORPHOLINOETHYL)-1H-PYRAZOL-4-BORONIC ACID PINACOL ESTER;1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER;4-{2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyr...;1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester 97%;1-(2-Morpholin-4-ylethyl)-1H-pyrazol-4-ylboronic acid pinacol ester
CBNumber
CB8707033
Molecular Formula
C15H26BN3O3
Formula Weight
307.2
MOL File
864754-18-7.mol
More
Less

1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Property

Melting point:
89-94℃
Boiling point:
440.6±35.0 °C(Predicted)
Density 
1.15±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder
pka
6.71±0.10(Predicted)
Appearance
White to off-white Solid
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36-38
Safety Statements 
26
WGK Germany 
2
HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
706213
Product name
1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester
Purity
97%
Packaging
250mg
Price
$232
Updated
2025/07/31
Sigma-Aldrich
Product number
706213
Product name
1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester
Purity
97%
Packaging
1g
Price
$477
Updated
2025/07/31
TRC
Product number
M732775
Product name
1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester
Packaging
500mg
Price
$110
Updated
2021/12/16
Synthonix
Product number
T10045
Product name
4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)morpholine
Purity
90+%
Packaging
1g
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
094585
Product name
4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)morpholine
Purity
95+%
Packaging
250mg
Price
$213
Updated
2021/12/16
More
Less

1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

269410-08-4

3647-69-6

864754-18-7

GENERAL STEPS: N-(2-chloroethyl)morpholine hydrochloride (1.25 g, 6.70 mmol) was added to a solution of anhydrous N,N-dimethylformamide (20 mL) containing pinacol ester of 4-pyrazoleboronic acid (1.00 g, 5.15 mmol) and cesium carbonate (5.54 g, 17.01 mmol) at 0 °C. After stirring for 30 min, the ice water bath was removed. The reaction mixture was continued to be stirred at room temperature for 4 days. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (150 mL) and washed with brine (3 x 100 mL). The organic layer was dried with anhydrous sodium sulfate and subsequently concentrated under reduced pressure. The crude product was purified by fast column chromatography (Method L7; 12 g silica gel; eluent: ethyl acetate) to afford 1-(2-morpholinylethyl)-1H-pyrazole-4-boronic acid pinacol ester 0.75 g (2.44 mmol, 47% yield). analysis by GC-MS (Method L9) showed R1 = 5.49 min; (no mass detected).1H NMR ( 300 MHz, chloroform-d, method M2) δ 7.80-7.75 (m, 1H), 7.73 (s, 1H), 4.25 (t, J = 6.8 Hz, 2H), 3.73-3.44 (m, 4H), 2.81 (t, J = 6.8 Hz, 2H), 2.50-2.42 (m, 4H), 1.32 (s, 12H).

References

[1] Patent: WO2017/178416, 2017, A1. Location in patent: Page/Page column 116
[2] Patent: WO2010/75270, 2010, A1. Location in patent: Page/Page column 160

1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Suppliers

China 81 Germany 2 India 2 United Kingdom 2 United States 10 Global 97
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
716
Advantage
55
Tel
0519-81096292 15312577869
Email
chemscaler@yahoo.com.cn
Country
China
ProdList
311
Advantage
60
Tel
021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
896
Advantage
55
Tel
020-82185713,82185709 13418171485
Fax
020-82185696
Email
sales@chem-stone.com
Country
China
ProdList
744
Advantage
56
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Tel
18698614691
Fax
0411-84986229
Email
niche_biomedicine@163.com
Country
China
ProdList
63
Advantage
60
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
Tel
0731-88827538 15873153880
Fax
0731-88827238
Email
luxingbc@126.com
Country
China
ProdList
1999
Advantage
65
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Tel
18602194589
Email
lincy-110@163.com
Country
China
ProdList
863
Advantage
58
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Tel
022-66200236 18622210341
Fax
+86-022-66200236
Email
sales@atop-biotech.com
Country
China
ProdList
295
Advantage
60
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9148
Advantage
60
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tel
18511709189
Fax
010-58043593
Email
sales@hechemist.com
Country
China
ProdList
2835
Advantage
58
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Tel
13917627064
Fax
-qq：56229367
Email
56229367@qq.com
Country
China
ProdList
634
Advantage
58
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9911
Advantage
58
Tel
+86 028-84641798 15982321820
Email
abby@arkpharm.com
Country
China
ProdList
10000
Advantage
58
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
Tel
027-67849912
Email
sales@chemwish.com
Country
CHINA
ProdList
10821
Advantage
58
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
Tel
16621358918
Fax
QQ:402135374
Email
botuopharma888@163.com
Country
China
ProdList
9208
Advantage
58
Tel
0371-0371-55153829 18003835034
Email
2853979819@qq.com
Country
China
ProdList
9998
Advantage
58
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
More
Less

View Lastest Price from 1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER manufacturers

Career Henan Chemical Co
Product
1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER 864754-18-7
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-22

864754-18-7, 1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTERRelated Search:

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester 4-Pyrazoleboronic acid pinacol ester 1-Methyl-1H-pyrazole-4-boronic acid 1H-PYRAZOLE-4-BORONIC ACID 1-Methyl-4-pyrazole boronic acid pinacol ester 1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER

  • 1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
  • 4-(2-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YL]-ETHYL)-MORPHOLINE
  • 1-(2-MORPHOLINOETHYL)-1H-PYRAZOL-4-BORONIC ACID PINACOL ESTER
  • 1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazole-4-boronic acid, pinacol ester
  • 4-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)morpholine
  • Morpholine, 4-[2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethyl]-
  • 1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazole-4-boronic acid, pinacol ester 98%
  • 1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid
  • 4-{2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethyl}Morpholine
  • 1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester 97%
  • 1-(2-Morpholinoethyl)pyrazole-4-boronic Acid Pinacol Ester
  • 1-(2-Morpholinoethyl)-1<I>H</I>-pyrazole-4-boronic acid pinacol ester
  • inoethyL
  • 1-(2-MorphoL
  • 4-{2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyr...
  • 1-(2-Morpholin-4-ylethyl)-1H-pyrazol-4-ylboronic acid pinacol ester
  • 1-(2-Morpholinoethyl)-1<I>H<
  • 4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)morpholine - [T10045]
  • 864754-18-7
  • C15H26BN3O3
  • Boronate Esters
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Heteroaryl Boronate Esters
  • Organometallic Reagents