ChemicalBook > CAS DataBase List > SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE

Product Name
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
CAS No.
125494-59-9
Chemical Name
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
Synonyms
SIBUTRAMINE HCL MONOHYDRATE;Sibutramine sib;SibutramineHClH2O;SIBUTRAMINE HCL HYDRATE;)-SibutraMine-d6 HCl H2O;BTS-54524, Reductil, Meridia;SIBUTRAMINE HYDROCHLORIDE HYDRATE;Sibutramine hydrochloride solution;Sibutramine Hydrochloride Monohydra;SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
CBNumber
CB8708494
Molecular Formula
C17H29Cl2NO
Formula Weight
334.32
MOL File
125494-59-9.mol
More
Less

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Property

Melting point:
193-195.5°C
Flash point:
9℃
storage temp. 
Room temp
solubility 
DMSO: >30mg/mL
form 
solid
color 
white
More
Less

Safety

Hazard Codes 
Xi,T,F
Risk Statements 
36/37/38-39/23/24/25-23/24/25-11
Safety Statements 
22-24/25-36-26-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BS164401
Product name
Sibutramine hydrochloride monohydrate
Packaging
10mg
Price
$96
Updated
2021/12/16
Biosynth Carbosynth
Product number
BS164401
Product name
Sibutramine hydrochloride monohydrate
Packaging
50mg
Price
$337
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000830
Product name
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
Purity
95.00%
Packaging
25MG
Price
$704.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000830
Product name
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
Purity
95.00%
Packaging
250MG
Price
$1593.9
Updated
2021/12/16
DC Chemicals
Product number
DCAPI1430
Product name
sibutraminehydrochloride
Purity
>99%
Packaging
1g
Price
$1000
Updated
2021/12/16
More
Less

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Chemical Properties,Usage,Production

Description

Sibutramine was introduced as Meridia in the US for the control of obesity, in conjunction with a reduced-calorie diet. Sibutramine can be prepared in four steps from 4-chlorobenzyl cyanide. Sibutramine acts as a serotonin and noradrenaline reuptake inhibitor ; in animal studies, it reduces energy intake by creating a satieted feeling and increases energy expenditure by enhancing thermogenesis. In a clinical study in obese patients treated with 10 or 15 mg of Sibutramine once-daily, meaningful weight loss was sustained for 12 months ; an additional study demonstrated a lack of abuse potential. An appreciable part of Sibutramine's effect would also be due to its 2N-mono and didesmethylmetabolites, which are very potent monoamine reuptake inhibitors themselves.

Chemical Properties

White Solid

Originator

Knoll (Germany)

Uses

A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure

Uses

antiobesity agent;neurotransmitter reuptake inhibitor

Uses

antihyperlipidemic

brand name

Meridia (Abbott);Meridia, Reductil.

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Suppliers

Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
Advantage
62
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
More
Less

View Lastest Price from SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE manufacturers

Zhejiang kaitao Import and export Co. LTD
Product
Sibutramine Hydrochloride Monohydrate 125494-59-9
Price
US $1300.00/Kg/Bag
Min. Order
100g
Purity
99.4%
Supply Ability
1000GK
Release date
2021-10-29
Zhejiang Lihui import and export Co. LTD
Product
Sibutramine Hydrochloride Monohydrate 125494-59-9
Price
US $1300.00/g/Bag
Min. Order
100g/Bag
Purity
99.8%
Supply Ability
2000kg
Release date
2021-10-27
Career Henan Chemical Co
Product
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE 125494-59-9
Price
US $1.00-2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

125494-59-9, SIBUTRAMINE HYDROCHLORIDE MONOHYDRATERelated Search:


  • [1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl-butyl]-dimethyl-amine hydrate hydrochloride
  • 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride
  • 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrate hydrochloride
  • 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
  • Sibutramine Hydrochloride CIV (125 mg)
  • )-SibutraMine-d6 HCl H2O
  • 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride
  • CyclobutaneMethanaMine,1-(4-chlorophenyl)-N,N-diMethyl-a-(2-Methylpropyl)-, hydrochloride, hydrate (1:1:1)
  • Sibutramine hydrochloride solution
  • SibutramineHClH2O
  • BTS-54524, Reductil, Meridia
  • Meridia, Reductil, 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine monohydrate hydrochloride
  • Sibutramine monohydrate hydrochloride
  • 1-(1-(4-chlorophenyl)cyclobutyl)-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
  • SIBUTRAMINE HCL HYDRATE
  • SIBUTRAMINE HCL MONOHYDRATE
  • SIBUTRAMINE HYDROCHLORIDE HYDRATE
  • SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
  • Sibutramine sib
  • Sibutramine Hydrochloride Monohydrate Standard
  • Sibutramine Hydrochloride Monohydra
  • Sibutramine hydrochloride solution in Methanol,1000ug/ml
  • Sibutramine Hydrochloride MonohydrateQ: What is Sibutramine Hydrochloride Monohydrate Q: What is the CAS Number of Sibutramine Hydrochloride Monohydrate Q: What is the storage condition of Sibutramine Hydrochloride Monohydrate Q: What are the applications of Sibutramine Hydrochloride Monohydrate
  • Sibutramine Hydrochloride CIV (1612845)
  • 125494-59-9
  • C17H19D7ClNHCl
  • C17H26ClNxHClxH2O
  • C16H24ClNHCl
  • C17H26ClNHClH2O
  • 33432
  • CRESTOR
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Anilines, Aromatic Amines and Nitro Compounds