ETHYL 2-METHYL-3-INDOLEACETATE Property

Melting point:

95 °C(Solv: ethyl ether (60-29-7))

Boiling point:

195-196 °C/3.5 mmHg (lit.)

Density 

1.11 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.571(lit.)

Flash point:

>230 °F

pka

17.27±0.30(Predicted)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

ETHYL 2-METHYL-3-INDOLEACETATE Chemical Properties,Usage,Production

Uses

• ;Reactant for preparation of hydroxamate derivatives as HDAC inhibitor with anticancer activity1• ;Reactant for stereoselective preparation of AG-041R, as a Potent Gastrin/CCK-B Receptor Antagonist2

Uses

• Reactant for preparation of hydroxamate derivatives as HDAC inhibitor with anticancer activity
• Reactant for stereoselective preparation of AG-041R, as a Potent Gastrin/CCK-B Receptor Antagonist

General Description

Ethyl 2-methyl-3-indoleacetate, also known as ethyl 2-(2-methyl-1H-indol-3-yl)acetate, is a substituted 1H-indole.