ChemicalBook > CAS DataBase List > Benzo-18-crown-6

Benzo-18-crown-6

Product Name
Benzo-18-crown-6
CAS No.
14098-24-9
Chemical Name
Benzo-18-crown-6
Synonyms
2,3,5,6,8,9,11,12,14,15-decahydrobenzo[b][1,4,7,10,13,16]hexaoxacyclooctadecine;BENZO-18-CROWN-6;Benzo-18-crown-6,97%;Benzo-18-crown-6 98%;Monobenzo-18-crown-6;BENZO-18-CROWN-6 99+%;BENZO-18-CROWN 6-ETHER;1,2$l^{2}-azaboretidine;Benzo-18-crown-6, 97% 1GR;Benzo-18-crown 6-Ether >
CBNumber
CB8727150
Molecular Formula
C16H24O6
Formula Weight
312.36
MOL File
14098-24-9.mol
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Benzo-18-crown-6 Property

Melting point:
42-45 °C (lit.)
Boiling point:
412.28°C (rough estimate)
Density 
1.1858 (rough estimate)
refractive index 
1.4795 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
very faint turbidity in Methanol
form 
Liquid
color 
Clear colorless
Sensitive 
Hygroscopic
BRN 
1626123
InChI
InChI=1S/C16H24O6/c1-2-4-16-15(3-1)21-13-11-19-9-7-17-5-6-18-8-10-20-12-14-22-16/h1-4H,5-14H2
InChIKey
DSFHXKRFDFROER-UHFFFAOYSA-N
SMILES
O1C2=CC=CC=C2OCCOCCOCCOCCOCC1
CAS DataBase Reference
14098-24-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
22-24/25-37/39-26
WGK Germany 
3
3
HazardClass 
IRRITANT
HS Code 
29329985
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
372293
Product name
Benzo-18-crown-6
Purity
98%
Packaging
5g
Price
$162
Updated
2023/06/20
TCI Chemical
Product number
B1539
Product name
Benzo-18-crown 6-Ether
Purity
>96.0%(GC)
Packaging
1g
Price
$72
Updated
2025/07/31
TCI Chemical
Product number
B1539
Product name
Benzo-18-crown 6-Ether
Purity
>96.0%(GC)
Packaging
5g
Price
$287
Updated
2025/07/31
TRC
Product number
B130068
Product name
Benzo-18-crown-6
Packaging
500mg
Price
$130
Updated
2021/12/16
SynQuest Laboratories
Product number
2H11-1-02
Product name
Benzo-18-crown-6
Packaging
250mg
Price
$85
Updated
2021/12/16
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Benzo-18-crown-6 Chemical Properties,Usage,Production

Chemical Properties

white granular powder and chunks

Uses

Benzo-18-crown-6-ether (B18C6) is an organic compound that can be used to prepare stable microcapsule responsive layers for further assembly into bilayer microcapsules. For example, 18-Crown-6-ether is used to prepare the response layer and is coated with a G-quadruplex cross-linked hydrogel layer stabilized by K+; when Mg2+ ions are present, 18-Crown-6-ether and K+ ions can respectively Dissociates and locks with the G-quadruplex cross-linked layer, thereby achieving switchable controlled release of the load[1].

Purification Methods

Purify it by passage through a DEAE cellulose column in cyclohexane. It recrystallises from n-hexane. Its thiourea complex has m 127o [5-6 mol of urea to ether, Pedersen J Org Chem 36 1690 1971]. The stability constants of the Na+, K+, Rb+, Cs+, Tl+ and Ba2+ complexes are described in Hofmanova et al. Inorg Chim Acta 28 73 1978. [NMR: Live & Chan J Am Chem Soc 98 3769 1976]. [Beilstein 19/12 V 618.] IRRITANT.

References

[1] Ehala S, et al. Application of affinity capillary electrophoresis and density functional theory to the investigation of benzo-18-crown-6-ether complex with ammonium cation. J Chromatogr A. 2009 Nov 6;1216(45):7927-31. DOI:10.1016/j.chroma.2009.09.034

Benzo-18-crown-6 Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzo-18-crown-6 Suppliers

Wuxi InterpiPharm, Inc.
Tel
510-83782303 13771177691
Fax
0510- 8378-9906
Email
sales@itppharm.com
Country
China
ProdList
110
Advantage
62
Wuhan EEChem Technologies Co., Ltd
Tel
0711-3617768 13308685235
Fax
0711-3616558
Email
lihongcai4360@sina.com
Country
China
ProdList
1510
Advantage
55
Shanghai Kuokun Biotechnology Co., Ltd
Tel
15900929397
Email
3154863169@qq.com
Country
China
ProdList
309
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
5061
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32035
Advantage
58
Puyang Borui Technology Development Co., Ltd
Tel
15203933070
Email
450281857@qq.com
Country
China
ProdList
96
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Sichuan Zhongbang Pharma CO.,LTD
Tel
0830-0830-2585019 13679670161
Fax
0830-2589033
Email
sales2@zhongbangst.com
Country
China
ProdList
105
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Benzo-18-crown-6 manufacturers

Dideu Industries Group Limited
Product
Benzo-18-crown-6 14098-24-9
Price
US $1.10/g
Min. Order
1g
Purity
99.0% Min
Supply Ability
100 Tons Min
Release date
2025-09-19
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Benzo-18-crown-6 14098-24-9
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-27
LY Global chemicals co.,ltd .
Product
Benzo-18-crown-6 14098-24-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98% Min
Supply Ability
1000kg
Release date
2023-03-18

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