ChemicalBook > CAS DataBase List > Emedastine

Emedastine

Product Name
Emedastine
CAS No.
87233-61-2
Chemical Name
Emedastine
Synonyms
EMEDASTINE;Emedastine impurity F;Emedastine Impurity 14;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole;1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole;1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole;1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole;1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole;allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis
CBNumber
CB8728076
Molecular Formula
C17H26N4O
Formula Weight
302.41
MOL File
87233-61-2.mol
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Emedastine Property

Boiling point:
446.6±55.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 125 mg/mL (413.35 mM); Ethanol: 100 mg/mL (330.68 mM)
pka
8.86±0.10(Predicted)
CAS DataBase Reference
87233-61-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0028590
Product name
Emedastine
Purity
≥98.0%
Packaging
5mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009136
Product name
EMEDASTINE
Purity
95.00%
Packaging
5MG
Price
$496.67
Updated
2021/12/16
ChemScene
Product number
CS-0028590
Product name
Emedastine
Purity
≥98.0%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0028590
Product name
Emedastine
Purity
≥98.0%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0028590
Product name
Emedastine
Purity
≥98.0%
Packaging
100mg
Price
$2250
Updated
2021/12/16
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Emedastine Chemical Properties,Usage,Production

Uses

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

Definition

ChEBI: 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the ifumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

brand name

Emadine (Alcon).

Clinical Use

Emedastine also is a newer antihistamine used topically in the eye for conjunctivitis. It has very high H1 receptor selectivity characteristics, and it is structurally related to the benzimidazoles, such as astemizole. Inhibition of mast cell release of inflammatory mediators has been noted.

Emedastine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Emedastine manufacturers

Career Henan Chemical Co
Product
Emedastine 87233-61-2
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-14

87233-61-2, EmedastineRelated Search:


  • EMEDASTINE
  • 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole
  • 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole
  • 1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole
  • 1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole
  • 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
  • 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole
  • Emedastine impurity F
  • allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis
  • Emedastine Impurity 14
  • 87233-61-2
  • C17H26N4O
  • impurity
  • DCP