ChemicalBook > CAS DataBase List > 2'-BROMOACETANILIDE

2'-BROMOACETANILIDE

Product Name
2'-BROMOACETANILIDE
CAS No.
614-76-6
Chemical Name
2'-BROMOACETANILIDE
Synonyms
N-(2-BROMOPHENYL)ACETAMIDE;2-BROMOACETANILIDE;NISTC614766;o-Bromoacetanilide;2'-Bromoacetanilide;Acetanilide, 2'-bromo-;2'-Bromoacetanilide >N-Acetyl-2-bromoaniline;2-Bromo-N-acetylaniline;2'-Bromoacetanilide, 98+%
CBNumber
CB8742191
Molecular Formula
C8H8BrNO
Formula Weight
214.06
MOL File
614-76-6.mol
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2'-BROMOACETANILIDE Property

Melting point:
96.5-100.5 °C(lit.)
Boiling point:
346.8±25.0 °C(Predicted)
Density 
1.543±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.19±0.70(Predicted)
form 
Crystalline Powder
color 
White
BRN 
2086970
CAS DataBase Reference
614-76-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3139
Product name
2'-Bromoacetanilide
Purity
>98.0%(GC)
Packaging
5g
Price
$90
Updated
2025/07/31
TCI Chemical
Product number
B3139
Product name
2'-Bromoacetanilide
Purity
>98.0%(GC)
Packaging
25g
Price
$285
Updated
2023/06/20
TRC
Product number
B679010
Product name
2''-Bromoacetanilide
Packaging
50g
Price
$250
Updated
2021/12/16
TRC
Product number
B679010
Product name
2''-Bromoacetanilide
Packaging
25g
Price
$165
Updated
2021/12/16
Apolloscientific
Product number
OR4339
Product name
2'-Bromoacetanilide
Packaging
25g
Price
$66
Updated
2021/12/16
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2'-BROMOACETANILIDE Chemical Properties,Usage,Production

Uses

2''-Bromoacetanilide is used as a reagent in the preparation of furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ.

Synthesis

108-24-7

615-36-1

614-76-6

General procedure for the synthesis of 2'-bromoacetanilide from ethanoic anhydride and o-bromoaniline: o-bromoaniline (22.0 g, 128 mmol), acetic anhydride (13.06 g, 128 mmol) and a catalytic amount of 4-dimethylaminopyridine (DMAP) were dissolved in dichloromethane (100 mL), and stirred at 0 °C. The reaction mixture was slowly warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction mixture was washed with saturated aqueous sodium bicarbonate solution and subsequently concentrated. The concentrated residue was ground with a solvent mixture of hexane/dichloromethane, the solid product was collected by filtration and rinsed with hexane to give 2'-bromoacetanilide (25.4 g, 92.8% yield). The high performance liquid chromatography (HPLC) retention time (Rt) was 1.523 min.

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 11, p. 2187 - 2196
[2] Organic Letters, 2004, vol. 6, # 19, p. 3293 - 3296
[3] Organic Letters, 2016, vol. 18, # 22, p. 5896 - 5899
[4] Dyes and Pigments, 2018, vol. 159, p. 419 - 428
[5] Patent: US2005/192310, 2005, A1. Location in patent: Page/Page column 20

2'-BROMOACETANILIDE Preparation Products And Raw materials

Raw materials

Hexane Acetic anhydride 2-Bromoaniline Sodium bicarbonate Dichloromethane 4-Dimethylaminopyridine

Preparation Products

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2'-BROMOACETANILIDE Suppliers

Americas 1 China 107 Europe 1 Germany 3 India 5 Japan 1 Switzerland 1 The Netherlands 2 Ukraine 1 United Kingdom 5 United States 21 Global 148
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from 2'-BROMOACETANILIDE manufacturers

Honest Joy Holdings Limited
Product
2-Bromoacetanilide 614-76-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.7%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
2'-BROMOACETANILIDE 614-76-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-08

614-76-6, 2'-BROMOACETANILIDERelated Search:

2'-Bromo-4'-fluoroacetanilide 2',4'-DIBROMOACETANILIDE 2'-BROMOACETANILIDE 4-Acetyl-2-bromoacetanilide 2-BROMO-4'-(TRIFLUOROMETHYL)ACETANILIDE 2'-BROMO-4'-METHYLACETANILIDE 4'-BROMOACETANILIDE,4-BROMOACETANILIDE,P-BROMOACETANILIDE,4'-Bromoacetanilide 250,Bromoacetanilide,P-BROMOACETANILIDE, 98% (SEE 1735),p-BROMOACETANILIDE pure 2-METHYL-4-BROMOACETANILIDE N-Methyl-2-bromoacetanilide 3'-BROMOACETANILIDE,m-bromoacetanilid 4-AMINO-2,6-DIBROMOACETANILIDE N-(2-BROMO-4-ISOPROPYL-PHENYL)-ACETAMIDE 2-CHLORO-N-(2,6-DIBROMO-4-METHYLPHENYL)ACETAMIDE 2'-BROMO-4'-CHLOROACETANILIDE N-(2-BROMO-4-NITRO-PHENYL)-2-CHLORO-ACETAMIDE N-(2-BROMOPHENYL)-3-PHENYLPROP-2-ENAMIDE 2'-BROMO-5'-FLUORO-4'-METHYLACETANILIDE N-(2-BROMOPHENYL)PHTHALIMIDE

  • 2-Bromo-N-acetylaniline
  • Acetanilide, 2'-bromo-
  • o-Bromoacetanilide
  • 2-BROMOACETANILIDE
  • N-(2-BROMOPHENYL)ACETAMIDE
  • 2'-Bromoacetanilide, 98+%
  • N-(2-bromophenyl)ethanamide
  • AcetaMide, N-(2-broMophenyl)-
  • NISTC614766
  • N-Acetyl-2-bromoaniline
  • 2'-Bromoacetanilide &gt
  • 2'-BROMOACETANILIDE ISO 9001：2015 REACH
  • 2'-Bromoacetanilide
  • 2′-Bromoacetanilide, CAS 614-76-6
  • 614-76-6
  • C8H8NOBr
  • Protected Amines
  • Nitrogen Compounds
  • Organic Building Blocks
  • Building Blocks
  • Anilines, Amides & Amines
  • Bromine Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines