ChemicalBook > CAS DataBase List > Fluorescamine

Fluorescamine

Product Name
Fluorescamine
CAS No.
38183-12-9
Chemical Name
Fluorescamine
Synonyms
FLURAM;Fluaram;FLURAM(R);RO 20-7234;Fluorescamin;FLUORESCAMINE;FluorescamineA.R.;Fluorescamine, pure;FLURAMANALYTICAL GRADE;Fluorescamine Labeling
CBNumber
CB8755458
Molecular Formula
C17H10O4
Formula Weight
278.26
MOL File
38183-12-9.mol
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Fluorescamine Property

Melting point:
153-157 °C (lit.)
Boiling point:
381.08°C (rough estimate)
Density 
1.2661 (rough estimate)
refractive index 
1.5447 (estimate)
Flash point:
-17 °C
storage temp. 
room temp
solubility 
acetonitrile: soluble
form 
powder
color 
off-white to yellow
Water Solubility 
Soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water.
Merck 
14,4158
BRN 
921143
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
38183-12-9(CAS DataBase Reference)
NIST Chemistry Reference
Spiro[furan-2(3h),1'(3'h)-isobenzofuran]-3,3'-dione, 4-phenyl-(38183-12-9)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/38-66-67-36-36/37/38
Safety Statements 
22-24/25-36/37-33-29-26-16-9-37/39
RIDADR 
UN 1090 3/PG 2
WGK Germany 
3
F 
10-21
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0192
Product name
Fluorescamine [for HPLC Labeling]
Packaging
100mg
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
F0192
Product name
Fluorescamine [for HPLC Labeling]
Packaging
1g
Price
$438
Updated
2024/03/01
Alfa Aesar
Product number
043749
Product name
Fluorescamine
Packaging
25mg
Price
$33.8
Updated
2024/03/01
Alfa Aesar
Product number
043749
Product name
Fluorescamine
Packaging
100mg
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
F9015
Product name
Fluorescamine
Purity
≥98% (TLC), powder, used for detection of primary amines
Packaging
100mg
Price
$133
Updated
2024/03/01
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Fluorescamine Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

For fluorescent detection of amino acids, peptides and proteins.Fluorescamine plays an important role as a reagent for the detection of amines, peptides and proteins. It is also used as a substrate for measuring protease activity. It is utilized in the detection and quantitation of residual aminopenicillins and sulfonamides in honey by HPLC. It finds application in the determination of lisinopril in human plasma and urine.

Uses

Fluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.

Uses

Analytical reagent.

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 5927, 1972 DOI: 10.1021/ja00771a084

Purification Methods

Fluram is a non-fluorescent reagent that reacts with primary amines to form highly fluorescent compounds. Purify it by dissolving (~1g) in Et2O/*C6H6 (1:1, 180 mL), washing with 1% aqueous NaHCO3 (50mL), drying (Na2SO4), and evaporating in a vacuum. Dissolve the residue in warm CH2Cl2 (5mL), dilute with Et2O (12mL) and refrigerate. Collect the solid and dry it in a vacuum. IR (CHCl3): 1810, 1745, 1722, 1625 and 1600 cm-1, and 1HNMR (CDCl3): 8.71 (s, -OHC=). [Weigele et max al. J Am Chem Soc 94 5927 1972, Weigele et al. J Org Chem 41 388 1976, Lai Methods Enzymol 47 236 1977.] Forskolin (Colforsin, Coleonol, 5-[acetyloxy]-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7, 10a-penta-methyl-[3R -{3

Fluorescamine Preparation Products And Raw materials

Raw materials

Ethanol Diethyl phthalate TRIS(DIMETHYLAMINO)METHANE Piperidine Hydrogen peroxide Sodium Chloroform Aluminum chloride Benzaldehyde Diethyl ether Benzene Hydrochloric acid Government regulation Methanol Sodium hydroxide N,N-Dimethylformamide dimethyl acetal Ammonium acetate Benzoic acid Dimethylamine 2-Acetylbenzoic acid Malonic acid

Preparation Products

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Fluorescamine Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 166 Europe 4 Germany 6 India 17 Japan 3 Lithuania 2 Poland 2 South Korea 1 Switzerland 5 Ukraine 3 United Kingdom 11 United States 31 Global 255
Changzhou Jianuokang Pharmaceutical Co., Ltd.
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View Lastest Price from Fluorescamine manufacturers

Career Henan Chemical Co
Product
Fluorescamine 38183-12-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98-99.9%
Supply Ability
100kg
Release date
2020-02-03

38183-12-9, FluorescamineRelated Search:

Fluorescent Brightener 28 Tetrahydrofuran Furan Fluorescein Sodium Fluorescein diacetate Fura 2-AM FLUORESCIN Fluorescein GLYCERYL MONOSTEARATE STEARIC ACID HYDRAZIDE Fluorescent powder ACETIC ACID 3-PHENYL-BUT-3-ENYL ESTER 4-Phenyl-2-butanol 2,3-Dihydrofuran 1-PHENYL-2-BUTANONE 3-ACETOXY-2-BUTANONE 1,2-Benzenedimethanol POLY(TETRAHYDROFURAN) STANDARD 15000

  • FLUORESCAMINE
  • FLUORESCAMINE SPRAY REAGENT
  • FLURAM
  • FLURAM(R)
  • 4'-PHENYL-SPIRO[2-BENZOFURAN-1(3H),2'(3'H)-FURAN]-2',3-DIONE
  • 4-PHENYL SPIRO-[FURAN-2(3H),1-PHTHALAN]-3,3'-DIONE
  • 4-PHENYLSPIRO[FURAN-2(3H),1'-PHTHALAN]-3,3'-DIONE
  • SPIRO[FURAN-2(3H),1'(3'H)-ISOBENZOFURAN]-3,3'-DIONE, 4-PHENYL-
  • RO 20-7234
  • 4-phenylspiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione
  • Fluorescamine [for HPLC Labeling]
  • FLURAM(R) (FLUORESCAMINE), FOR FLUORESCE NCE
  • FluorescamineA.R.
  • Fluorescamine, pure
  • FLUORESCAMINE extrapure AR
  • 4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3μ-dione, Fluorescamine
  • Supelco(R) TLC Spray Reagents
  • FLURAMANALYTICAL GRADE
  • Fluram,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione, Fluorescamine
  • Fluorescamine,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione
  • Fluorescamine, reagent grade
  • Fluorescamin
  • Fluaram
  • FluorescaMine, pure 100MG
  • FluorescaMine, pure 25MG
  • FluorescaMine, pure 500MG
  • 4-phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dione
  • 4'-phenylspiro[2-benzofuran-3,2'-furan]-1,3'-dione
  • Fluorescamine, For TLC analysis
  • Fluorescamine *CAS 38183-12-9*
  • Fluorescamine Labeling
  • Fluorescamine, 98%, for synthesis
  • 4''-phenyl-3H,3''H-spiro[2-benzofuran-1,2''-furan]-3,3''-dione
  • Fluorescamine extrapure AR, ExiPlus, Multi-Compendial, 99%
  • 4'-phenyl-3,3'-dihydrospiro[2-benzofur an-1,2'-furan]-3,3'-dione
  • Fluorescamine, 10 mM in DMSO
  • 38183-12-9
  • 39183-12-9
  • C17H10O4
  • Peptide Analysis and Characterization
  • Other Fluorescent Labels
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Labels
  • Functional Group Reactive Labels
  • Functional Group Reactive Labels for Flow Cytometry
  • Detection
  • Biochemicals and Reagents
  • Amino Acid Analysis Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Amino Acid Analysis
  • Amino Group Labeling Reagents for Fluorescence HPLC
  • HPLC Labeling Reagents
  • Fluorescence Detection (HPLC Labeling Reagents)
  • marker
  • Amino Acid Analysis
  • Amino Acid Analysis Reagents
  • Peptide Analysis and Characterization