ChemicalBook > CAS DataBase List > Fluorescamine

Fluorescamine

Product Name
Fluorescamine
CAS No.
38183-12-9
Chemical Name
Fluorescamine
Synonyms
FLURAM;Fluaram;FLURAM(R);RO 20-7234;Fluorescamin;FLUORESCAMINE;FluorescamineA.R.;Fluorescamine, pure;FLURAMANALYTICAL GRADE;Fluorescamine Labeling
CBNumber
CB8755458
Molecular Formula
C17H10O4
Formula Weight
278.26
MOL File
38183-12-9.mol
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Fluorescamine Property

Melting point:
153-157 °C (lit.)
Boiling point:
381.08°C (rough estimate)
Density 
1.2661 (rough estimate)
refractive index 
1.5447 (estimate)
Flash point:
-17 °C
storage temp. 
room temp
solubility 
acetonitrile: soluble
form 
powder
color 
off-white to yellow
Water Solubility 
Soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water.
Merck 
14,4158
BRN 
921143
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
38183-12-9(CAS DataBase Reference)
NIST Chemistry Reference
Spiro[furan-2(3h),1'(3'h)-isobenzofuran]-3,3'-dione, 4-phenyl-(38183-12-9)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/38-66-67-36-36/37/38
Safety Statements 
22-24/25-36/37-33-29-26-16-9-37/39
RIDADR 
UN 1090 3/PG 2
WGK Germany 
3
10-21
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0192
Product name
Fluorescamine [for HPLC Labeling]
Packaging
100mg
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
F0192
Product name
Fluorescamine [for HPLC Labeling]
Packaging
1g
Price
$438
Updated
2024/03/01
Alfa Aesar
Product number
043749
Product name
Fluorescamine
Packaging
25mg
Price
$33.8
Updated
2024/03/01
Alfa Aesar
Product number
043749
Product name
Fluorescamine
Packaging
100mg
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
F9015
Product name
Fluorescamine
Purity
≥98% (TLC), powder, used for detection of primary amines
Packaging
100mg
Price
$133
Updated
2024/03/01
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Fluorescamine Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

For fluorescent detection of amino acids, peptides and proteins.Fluorescamine plays an important role as a reagent for the detection of amines, peptides and proteins. It is also used as a substrate for measuring protease activity. It is utilized in the detection and quantitation of residual aminopenicillins and sulfonamides in honey by HPLC. It finds application in the determination of lisinopril in human plasma and urine.

Uses

Fluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.

Uses

Analytical reagent.

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 5927, 1972 DOI: 10.1021/ja00771a084

Purification Methods

Fluram is a non-fluorescent reagent that reacts with primary amines to form highly fluorescent compounds. Purify it by dissolving (~1g) in Et2O/*C6H6 (1:1, 180 mL), washing with 1% aqueous NaHCO3 (50mL), drying (Na2SO4), and evaporating in a vacuum. Dissolve the residue in warm CH2Cl2 (5mL), dilute with Et2O (12mL) and refrigerate. Collect the solid and dry it in a vacuum. IR (CHCl3): 1810, 1745, 1722, 1625 and 1600 cm-1, and 1HNMR (CDCl3): 8.71 (s, -OHC=). [Weigele et max al. J Am Chem Soc 94 5927 1972, Weigele et al. J Org Chem 41 388 1976, Lai Methods Enzymol 47 236 1977.] Forskolin (Colforsin, Coleonol, 5-[acetyloxy]-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7, 10a-penta-methyl-[3R -{3

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Fluorescamine Suppliers

Changzhou Jianuokang Pharmaceutical Co., Ltd.
Tel
0519-85202684; 13775120798
Fax
0519-85202684
Email
jnkpharmtech@163.com
Country
China
ProdList
298
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
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View Lastest Price from Fluorescamine manufacturers

Career Henan Chemical Co
Product
Fluorescamine 38183-12-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98-99.9%
Supply Ability
100kg
Release date
2020-02-03

38183-12-9, FluorescamineRelated Search:


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