4-Vinylpyridine

ChemicalBook > CAS DataBase List > 4-Vinylpyridine

Product Name: 4-Vinylpyridine
CAS No.: 100-43-6
Chemical Name: 4-Vinylpyridine
Synonyms: 4VP;4-Ethenylpyridine;4-vinylpyridine monomer;4-VINYLPYRIDINE;4-vinyl-pyridin;Vinylpyridine,4-;4-ethenyl-pyridin;4-Pyridylethylene;Pyridine, 4-vinyl-;gamma-vinylpyridine
CBNumber: CB8852582
Molecular Formula: C7H7N
Formula Weight: 105.14
MOL File: 100-43-6.mol

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4-Vinylpyridine Property

Melting point:: <25 °C
Boiling point:: 62-65 °C/15 mmHg (lit.)
Density: 0.975 g/mL at 25 °C (lit.)
vapor pressure: 2.28hPa at 25℃
refractive index: n20/D 1.549(lit.)
Flash point:: 125 °F
storage temp.: -20°C
solubility: Chloroform, Methanol (Slightly)
form: Liquid
pka: pK1:5.62(+1) (25°C)
color: Clear colorless to yellow-brown
Water Solubility: 29 G/L (20 ºC)
BRN: 104506
Exposure limits: ACGIH: TWA 1 mg/m3
OSHA: TWA 2 mg/m3
NIOSH: IDLH 50 mg/m3; Ceiling 2 mg/m3
Stability:: Stable. Incompatible with strong acids, strong oxidizing agents.
LogP: 1.36 at 20℃
CAS DataBase Reference: 100-43-6(CAS DataBase Reference)
NIST Chemistry Reference: Pyridine, 4-ethenyl-(100-43-6)
EPA Substance Registry System: 4-Vinylpyridine (100-43-6)

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Safety

Hazard Codes: T
Risk Statements: 10-25-34-42/43-23/25
Safety Statements: 23-26-36/37/39-45-28A-16
RIDADR: UN 3073 6.1/PG 2
WGK Germany: 3
RTECS: UU1045000
F: 8-10
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29333990
Hazardous Substances Data: 100-43-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: V3204
Product name: 4-Vinylpyridine
Purity: contains 100 ppm hydroquinone as inhibitor, 95%
Packaging: 5ml
Price: $27.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: V3204
Product name: 4-Vinylpyridine
Purity: contains 100 ppm hydroquinone as inhibitor, 95%
Packaging: 100ml
Price: $54
Updated: 2024/03/01

TCI Chemical

Product number: V0150
Product name: 4-Vinylpyridine (stabilized with HQ)
Purity: >95.0%(GC)
Packaging: 25mL
Price: $40
Updated: 2024/03/01

TCI Chemical

Product number: V0150
Product name: 4-Vinylpyridine (stabilized with HQ)
Purity: >95.0%(GC)
Packaging: 500mL
Price: $450
Updated: 2024/03/01

Alfa Aesar

Product number: H36621
Product name: 4-Vinylpyridine, 96%, low polymer, stab. with 100ppm hydroquinone
Packaging: 25ml
Price: $43.65
Updated: 2024/03/01

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4-Vinylpyridine Chemical Properties,Usage,Production

Description

4-vinylpyridine (4VP) is a pyridine derivative with a vinyl group in the 4-position. It is a colorless liquid, although impure samples are often brown. This compound belongs to a class of polar vinyl monomers that are important in many applications due to the ability of their polymers to form complexes of the electron-rich pyridine ring and to form polyelectrolytes through protonation or quaternization with alkyl or aryl halides. 4VP is sometimes used in biochemistry to alkylate protein cysteine residues. When compared to other alkylation agents, such as iodoacetamide, acrylamide, and N-ethylmaleimide, 4VP is less reactive, meaning the completion rate of cysteine alkylation is lower, but it also yields fewer side reactions[1].

Chemical Properties

dark brown to yellow liquid. 2.9g can be dissolved in 100g of water at 20℃, soluble in methanol, ether, benzene, acetone, and slightly soluble in ether. When exposed to light and heat, polymerization occurs, and 0.1%-0.2% hydroquinone is often added as a polymerization inhibitor during storage.

Uses

4-Vinylpyridine acts as a co-monomer in styrene-butadiene polymers to promote adhesion between the rubber compound and supporting fibers (or cords) in tires, belts and hoses. It serves as an intermediate for manufacturing chemicals and pharmaceuticals. Further, it is used as a reagent for the modification of cysteine. In addition to this, it is used to make poly(4-vinylpyridine) and elastomers.

Application

4-Vinylpyridine was used as a monomer in polymer chemistry and induced nonimmunological contact urticaria and allergic contact dermatitis. No crossreactivity is observed between pyridine derivatives. It can be copolymerized with many other monomers, in particular cationic monomers, such as acrylamide, acrylates, and also with other vinyl-based monomers (e.g. styrene).?

Preparation

4-Vinylpyridine is synthesized by reacting 4-picoline with formaldehyde to generate 4-pyridineethanol, which is then dehydrated.

Flammability and Explosibility

Flammable

Purification Methods

6 2 . Purify the monomer by fractional distillation under a good vacuum and in a N2 atmosphere and store it in sealed ampoules under N2, and keep it in the dark at -20o. The picrate has m 175-176o. [UV: Coleman & Fuoss J Am Chem Soc 77 5472 1955, Overberger et al. J Polymer Sci 27 381 1958, Petro & Smyth J Am Chem Soc 79 6142 1957.] It is used for alkylating SH groups in peptides [Anderson & Friedman Can J Biochem 49 1042 1971, Cawins & Friedman Anal Biochem 35 489 1970]. [Beilstein 20 II 170, 20 III/IV 2887, 20/6 V 213.]

References

[1] Baskaran, D. and A. Müller. “Anionic Polymerization of Polar Vinyl Monomers.” (2012): 623-655

4-Vinylpyridine Preparation Products And Raw materials

Raw materials

Potassium tert-butoxide 4-tert-Butylcatechol Potassium hydroxide 4-Pyridineethanol Methylene Blue trihydrate 4-Methylpyridine Formaldehyde Hydroquinone Potassium phosphate tribasic Sodium hydroxide 2-Aminophenol Potassium Acetate Sodium nitrate Rubidium nitrate Aluminum oxide Potassium nitrate

Preparation Products

4-PYRIDINEETHANETHIOL HYDROCHLORIDE 1-[2-(4-PYRIDYL)ETHYL]PIPERAZINE 2-PYRIDIN-4-YL-ETHANESULFONYL CHLORIDEHYDROCHLORIDE

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View Lastest Price from 4-Vinylpyridine manufacturers

Hebei Mojin Biotechnology Co., Ltd

Product: 4-Vinylpyridine 100-43-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-13

Hebei Guanlang Biotechnology Co., Ltd.

Product: 4-Vinylpyridine 100-43-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-03-02

Hebei Guanlang Biotechnology Co,.LTD

Product: 4-Vinylpyridine 100-43-6
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99% min
Supply Ability: 100tons
Release date: 2023-08-25

100-43-6, 4-VinylpyridineRelated Search:

Triethoxyvinylsilane Vinylmagnesium bromide 4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE VINYL PROPIONATE Vinyl resin POLY(4-VINYLPYRIDINE) Silicone rubber,methyl-vinyl alpha-Vinylpyridine,2-VINYLPYRIDINE Vinyl ester resin 1,2-BIS(2-PYRIDYL)ETHYLENE CYANINE 1,1'-DIETHYL-4,4'-CARBOCYANINE IODIDE 4-Pyridineacrylic acid N-Vinyl-2-pyrrolidone 4-(1-NAPHTHYLVINYL)PYRIDINE 3-(2-NITROETHENYL)PYRIDINE POLY(4-VINYLPYRIDINE) SULFUR TRIOXIDE COMPLEX F16

4-Ethenylpyridine

4-vinylpyridine monomer

Vinylpyridine,4-

4-Vinylpyridine, 96%, stab. with 100ppm hydroquinone

4-Vinylpyridine (stabilized with TBC)

4-Vinylpyridine, stabilized, 95+%

4-Vinylpyridine, 95%, stabilized

1-(4-Pyridinyl)ethene

4-Vinylpyridine, Stab. With 100Ppm Hydroquinone

4-Vinylpyridine ,95% [stabilized with TBC]

4-Vinylpyridine contains 100 ppM hydroquinone as inhibitor, 95%

4-Vinylpyridine, stabilized with 100ppm hydroquinone

4-Vinylpyridine, stabilized, 95% 100ML

4-Vinylpyridine, stabilized, 95% 250ML

4-Vinylpyridine, stabilized, 95%

4-Vinylpyridine, Stabilized(stabilized with TBC)

4-Vinylpyridine, 95%, stabilized with HQ

4-Vinylpyridine, stabilized with HQ

4-Vinylpyridine, 96%, low polyMer, stab. with 100ppM hydroquinone

4VP

4-VINYLPYRIDINE

4-ethenyl-pyridin

4-Pyridylethylene

4-vinyl-pyridin

gamma-vinylpyridine

Pyridine, 4-vinyl-

Pyridine,4-ethenyl-

4-Vinylpyridine (stabilized with hydroquinone)

4-Vinylpyridine ISO 9001：2015 REACH

4-Vinylpyridine（80-120ppm hydroquinone）

Tirofiban Impurity 41 (4-Vinylpyridine)

100-43-6

Organics

Monomers

Polymer Science

Vinyl Halides, Amines, Amides, and Other Vinyl Monomers