ChemicalBook > CAS DataBase List > N-Methyl-4-piperidinol

N-Methyl-4-piperidinol

Product Name
N-Methyl-4-piperidinol
CAS No.
106-52-5
Chemical Name
N-Methyl-4-piperidinol
Synonyms
1-methylpiperidin-4-ol;1-METHYL-4-PIPERIDINOL;4-Piperidinol, 1-methyl-;H431;NM4PPOL;-4-piperidinoL;N-Methylpiperidol;N-Methyl-4-hydroxy;TIMTEC-BB SBB004301;1-methyl-4-piperidino
CBNumber
CB8852683
Molecular Formula
C6H13NO
Formula Weight
115.17
MOL File
106-52-5.mol
More
Less

N-Methyl-4-piperidinol Property

Melting point:
29-31 °C(lit.)
Boiling point:
200 °C(lit.)
Density 
0.98 g/mL at 20 °C(lit.)
vapor pressure 
8.13-11Pa at 25℃
refractive index 
n20/D 1.479
Flash point:
190 °F
storage temp. 
2-8°C
form 
Liquid After Melting
pka
14.87±0.20(Predicted)
color 
Clear colorless to brown
Water Solubility 
MISCIBLE
Sensitive 
Hygroscopic
BRN 
103024
LogP
-0.14-0.756 at 25℃
CAS DataBase Reference
106-52-5(CAS DataBase Reference)
NIST Chemistry Reference
4-Hydroxy-N-methylpiperidine(106-52-5)
EPA Substance Registry System
4-Piperidinol, 1-methyl- (106-52-5)
More
Less

Safety

Hazard Codes 
Xi,C
Risk Statements 
37/38-41-36/37/38-34
Safety Statements 
26-37/39-45-36/37/39-27
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H42206
Product name
N-Methyl-4-piperidinol
Purity
98%
Packaging
100g
Price
$89.5
Updated
2024/03/01
TCI Chemical
Product number
M0933
Product name
4-Hydroxy-1-methylpiperidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
M0933
Product name
4-Hydroxy-1-methylpiperidine
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$223
Updated
2024/03/01
Alfa Aesar
Product number
L06415
Product name
4-Hydroxy-1-methylpiperidine, 98%
Packaging
100g
Price
$44.65
Updated
2024/03/01
Alfa Aesar
Product number
L06415
Product name
4-Hydroxy-1-methylpiperidine, 98%
Packaging
500g
Price
$149.65
Updated
2024/03/01
More
Less

N-Methyl-4-piperidinol Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellowish liquid after melting

Uses

Reactant for:• ;Optimization of Novobiocin scaffold to product antitumor agents1• ;Substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis2Reactant for synthesis of:• ;CaMKII inhibitors3• ;VEGFR and FGFR kinase inhibitors4• ;Phosphoinositide-3-kinase inhibitors5• ;Protein lysine methyltransferase G9a inhibitors6

Uses

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

Flammability and Explosibility

Not classified

N-Methyl-4-piperidinol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Methyl-4-piperidinol Suppliers

Alkemi BVBA
Tel
--
Fax
--
Email
nfo@alkemi.be
Country
Belgium
ProdList
2201
Advantage
58
Acros Organics (Part of Thermo Fisher Scientific )
Tel
--
Fax
--
Email
fo@acros.com
Country
Belgium
ProdList
3824
Advantage
58
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
More
Less

View Lastest Price from N-Methyl-4-piperidinol manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
1-Methyl-4-Hydroxypiperidine 106-52-5
Price
US $100.00-2000.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
5MT per Month
Release date
2021-01-15
Shaanxi Dideu Medichem Co. Ltd
Product
N-Methyl-4-piperidinol 106-52-5
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-08-05
Anhui Ruihan Technology Co., Ltd
Product
1-Methyl-4-piperidinol 106-52-5
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-21

106-52-5, N-Methyl-4-piperidinol Related Search:


  • 1-methyl-4-piperidino
  • 1-Methylpiperidinol-(4)
  • 4-Piperidinol, 1-methyl-
  • N-Methylpiperidol
  • 4-HYDROXY-1-METHYLPIPERIDINE
  • 4-HYDROXY-N-METHYLPIPERIDINE
  • N-METHYL-4-HYDROXY PIPERIDINE
  • NM4PPOL
  • N-METHYL-4-PIPERIDINOL
  • 1-HYDROXY-4-METHYLPIPERIDINE
  • 1-METHYL-4-PIPERIDINOL
  • 1-METHYL-4-PIPERIDINOL HCL
  • 1-METHYL-4-PIPERIDINOLHYDROCHOLORIDE
  • 1-METHYL-4-HYDROXYPIPERIDINE
  • TIMTEC-BB SBB004301
  • 1-methylpiperidin-4-ol
  • N-Methyl-4-hydroxy
  • 4-Hydroxy-1-methylpiperidine 98%
  • 1-Methyl-4-piperidinol, 4-Hydroxy-1-methylpiperidine
  • 4-Hydroxy-l-methylpiperidine
  • N-METIL-4-IDROSSIPIPERIDINA
  • 4-Hydroxy-N-Methylpiperidine, 98% 100GR
  • H431
  • 1- Methyl-4- piperidinealcohol
  • N-Methyl-4-piperidinol, 98%+
  • 4-Hydroxy-1-methylpiperidine,98%
  • N-Methyl-4-piperidinol 98%
  • 1-methyl-4-piperidin-1-iumol
  • Pimavanserin Impurity 12
  • 4-Hydroxy-1-methylpiperidine&gt
  • -4-piperidinoL
  • 4-Hydro xy-Ninethylp iperidine
  • Loratadine Impurity 40
  • N-Methyl-4-hydroxy-piperidine (NMHP)
  • 106-52-5 N-Methyl-4-piperidinol
  • 106-52-5
  • 102-52-5
  • Building Blocks
  • Heterocyclic Building Blocks
  • Piperidines
  • Building Blocks
  • C5 to C7
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Piperidines
  • PHARMACEUTICAL INTERMEDIATES
  • Piperidine