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ChemicalBook > CAS DataBase List > (R)-alpha,alpha-Diphenylmethylprolinol

(R)-alpha,alpha-Diphenylmethylprolinol

Reaction
Product Name
(R)-alpha,alpha-Diphenylmethylprolinol
CAS No.
144119-12-0
Chemical Name
(R)-alpha,alpha-Diphenylmethylprolinol
Synonyms
(2R)-(-)-N-Methyl-α;(R)-A,A-DIPHENYLMETHYLPROLINOL;a,a-Diphenyl-N-methyl-D-prolinol;à,à-diphenyl-n-methyl-d-prolinol;α,α-diphenyl-n-methyl-d-prolinol;1,1-Diphenyl-N-methyl-D-prolinol;α,α-diphenyl-N-Methyl-D-Prolinol;(R)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL;ALPHA,ALPHA-DIPHENYL-N-METHYL-D-PROLINOL;-diphenyl-2-pyrrolidinemethanol, min. 98%
CBNumber
CB8853099
Molecular Formula
C18H21NO
Formula Weight
267.37
MOL File
144119-12-0.mol
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(R)-alpha,alpha-Diphenylmethylprolinol Property

Melting point:
68-71 °C
alpha 
-52° (c=1, CHCl3)
Boiling point:
406.8±25.0 °C(Predicted)
Density 
1.116±0.06 g/cm3(Predicted)
refractive index 
-55 ° (C=1, CHCl3)
storage temp. 
Sealed in dry,Room Temperature
form 
Powder
pka
13.15±0.29(Predicted)
color 
white to light-yellow
optical activity
[α]20/D 55.0±4.0°, c = 1% in chloroform stab. with amylenes
BRN 
1535407
CAS DataBase Reference
144119-12-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
10-34
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
43118
Product name
α,α-Diphenyl-N-methyl-D-prolinol
Purity
≥99% (sum of enantiomers, GC)
Packaging
250mg
Price
$81.6
Updated
2023/06/20
TCI Chemical
Product number
H0784
Product name
(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine
Purity
>98.0%(GC)
Packaging
1g
Price
$157
Updated
2024/03/01
TCI Chemical
Product number
H0784
Product name
(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine
Purity
>98.0%(GC)
Packaging
5g
Price
$630
Updated
2024/03/01
Alfa Aesar
Product number
L19398
Product name
alpha,alpha-Diphenyl-N-methyl-D-prolinol, 97%
Purity
ee 99+%
Packaging
250mg
Price
$85
Updated
2021/12/16
Strem Chemicals
Product number
07-1170
Product name
(2R)-(-)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98%
Packaging
100mg
Price
$47
Updated
2024/03/01
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(R)-alpha,alpha-Diphenylmethylprolinol Chemical Properties,Usage,Production

Reaction

  1. Chiral amino alcohol assisted asymmetric, enantioselective, aryl transfer of triphenylboroxin to a set of aryl aldehydes in the presence of chiral amino alcohols derived from (S)-proline.
  2. Pyrrolidinylmethanol compound used for the zinc-catalyzed addition of arylboronic acids to aromatic aldehydes, proceeding in high yields and high enantioselectivities (up to 98% ee).

Chemical Properties

white to off-white crystalline powder

(R)-alpha,alpha-Diphenylmethylprolinol Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-alpha,alpha-Diphenylmethylprolinol Suppliers

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View Lastest Price from (R)-alpha,alpha-Diphenylmethylprolinol manufacturers

Career Henan Chemical Co
Product
(R)-alpha,alpha-Diphenylmethylprolinol 144119-12-0
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-24

144119-12-0, (R)-alpha,alpha-DiphenylmethylprolinolRelated Search:

D(-)Prolinol Methanol (S)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL N-Methyl-L-prolinol (R)-2-AMINO-1,2-DIPHENYL-1-PROPANOL (+)-N-METHYLEPHEDRINE (-)-Pseudoephedrine (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol (R)-alpha,alpha-Diphenylmethylprolinol (S)-2-Dimethylamino-1-phenyletanol N-Methyl-D-prolinol 2-BENZYLPYRROLIDINE (R)-1,1-DIPHENYL-2-AMINOPROPANE (R)-(+)-2-(DIPHENYLMETHYL)PYRROLIDINE (R,R)-(-)-2,6-BIS[2-(HYDROXYDIPHENYLMETHYL)-1-PYRROLIDINYL-METHYL]-4-METHYLPHENOL (R*,R*)-alpha-(1-aminoethyl)benzyl alcohol N-Methyl-DL-prolinol (1R,2R)-(-)-N-METHYLPSEUDOEPHEDRINE

  • (2R)-(-)-2-[Diphenyl(hydroxy)methyl]-1-methylpyrrolidine, (-)-alpha,alpha-Diphenyl-N-methyl-D-prolinol
  • (2R)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol
  • (2R)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol,99%e.e.
  • (2R)-(-)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98%
  • [(2R)-1-methylpyrrolidin-2-yl]-diphenylmethanol
  • (2R)-(-)-N-Methyl-α
  • -diphenyl-2-pyrrolidinemethanol, min. 98%
  • α,α-Diphenyl-N-methyl-D-prolinol, 98%, ee: 98%
  • (R)-(-)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE
  • (R)-A,A-N-METHYL DIPHENYL-2-PYRROLIDINE METHANOL
  • R-N-methyl-α,α-Diphenyl-2-pyrrolidinemethanol
  • (R)-(1-Methylpyrrolidin-2-yl)diphenylMethanol
  • α,α-Diphenyl-N-Methyl-D-prolinol >=99% (suM of enantioMers, GC)
  • α,α-Diphenyl-N-Methyl-D-prolinol, ee: 98%
  • (R)-A,A-DIPHENYLMETHYLPROLINOL
  • (R)-A,A-DIPHENYL-N-METHYL-2-PYRROLIDINEMETHANOL
  • (R)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL
  • (R)-ALPHA,ALPHA-DIPHENYL-N-METHYL-2-PYRROLIDINEMETHANOL
  • (R)-(-)-DIPHENYL(1-METHYLPYRROLIDIN-2-YL)METHANOL
  • (R)-N-METHYL- ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINE METHANOL
  • ALPHA,ALPHA-DIPHENYL-N-METHYL-D-PROLINOL
  • 1,1,1-DIPHENYL-(N-METHYL-PYRROLINE-2YL)-METHANOL
  • (2R)-1-METHYL-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL
  • (R)-N-Methyl-alpha,alpha-diphenylpyrrolidinemethanol
  • a,a-Diphenyl-N-methyl-D-prolinol
  • (R)-Diphenyl-N-methyl-2-pyrrolidinemethanol
  • (r)-n-methyl-à,à-diphenylpyrrolidinemethanol
  • à,à-diphenyl-n-methyl-d-prolinol
  • α,α-diphenyl-n-methyl-d-prolinol
  • 1,1-Diphenyl-N-methyl-D-prolinol
  • ALPHA,ALPHA-DIPHENYL-N-METHYL-D-PROLINOL , EE 99%
  • ɑ,ɑ-Diphenyl-N-methyl-D-prolinol, 97%, ee 99+%
  • (R)-N-Methyl-alpha,alpha-diphenyl-2-pyrrolidine
  • 1,1-DIPHENYL-(N-METHYL-PYRROLINE-2-YL)-METHANOL
  • alpha,alpha-Diphenyl-N-methyl-D-prolinol, 97%, ee 99+%
  • ^a,^a-Diphenyl-N-methyl-D-prolinol, 97%, ee 99+%
  • (R)-alpha,alpha-Diphenylmethylprolinol,98%
  • [( R)-α-Diphenyl-N-methyl-2-pyrrolidnemethanol]
  • (R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine&gt
  • (R)-N-Methyl-a,a-diphenyl-2-pyrrolidinemethanol
  • (R)-(1-Methyl-2-pyrrolidyl)diphenylmethanol
  • 2-Pyrrolidinemethanol, 1-methyl-α,α-diphenyl-, (2R)-
  • (R)-alpha,alpha-Diphenylmethylprolinol USP/EP/BP
  • 2-Pyrrolidinemethanol, 1-methyl-α,α-diphenyl-, (2R)-
  • α,α-diphenyl-N-Methyl-D-Prolinol
  • (2R)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol
  • 144119-12-0
  • 144199-12-0
  • Chiral Catalysts, Ligands, and Reagents
  • Asymmetric Synthesis
  • Proline-Based Organocatalysts
  • Asymmetric Synthesis
  • Synthetic Organic Chemistry