7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine

Product Name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
CAS No.: 34950-82-8
Chemical Name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Synonyms: 7-bromo-2H,3H,4H-pyrido[3,2-b][1,4]oxazine;7-bromo-3,4-dihydro-2H-pyrido[3,2-β][1,4]oxazine;7-BROMO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE;2H-Pyrido[3,2-b]-1,4-oxazine, 7-bromo-3,4-dihydro-
CBNumber: CB8853534
Molecular Formula: C7H7BrN2O
Formula Weight: 215.05
MOL File: 34950-82-8.mol

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7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Property

Melting point:: 116 °C
Boiling point:: 316.8±42.0 °C(Predicted)
Density: 1.619±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 7.32±0.20(Predicted)
form: solid
Appearance: Light yellow to green yellow Solid

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Safety

WGK Germany: 3
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE001250
Product name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Purity: Aldrich
Packaging: 1g
Price: $817
Updated: 2025/07/31

TRC

Product number: B699683
Product name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B699683
Product name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B699683
Product name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Matrix Scientific

Product number: 048483
Product name: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Packaging: 250mg
Price: $342
Updated: 2021/12/16

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7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Chemical Properties,Usage,Production

Synthesis

20348-23-6

34950-82-8

3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine (500 mg, 3.67 mmol) was used as starting material and dissolved in DMF (10 mL). To this solution was added N-bromosuccinimide (NBS, 719 mg, 4.04 mmol) at 0 °C. The reaction mixture was stirred continuously for 2 h at 0 °C. Upon completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 solution and stirring was continued for 20 min at 0 °C. The resulting precipitate was collected by filtration and the solid product was washed with water and dried under vacuum to afford 7-bromo-3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine (549 mg, 2.55 mmol, 69.5% yield) as a brown solid. The product was analyzed by mass spectrometry (ESI+) with a measured value of 215.2 (M + H).1H NMR (300 MHz, CDCl3) δ: 3.50-3.58 (2H, m), 4.18-4.26 (2H, m), 4.82 (1H, brs), 7.10 (1H, d, J = 1.9 Hz), 7.72 (1H, d, J = 2.3 Hz).

References

[1] Patent: WO2018/30550, 2018, A1. Location in patent: Paragraph 0596
[2] Patent: EP2341052, 2011, A1. Location in patent: Page/Page column 40
[3] Acta Chemica Scandinavica (1947-1973), 1971, vol. 25, p. 3135 - 3143
[4] Patent: KR101576386, 2015, B1. Location in patent: Paragraph 0158-0160

7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Suppliers

Belgium 1 China 63 India 1 United States 7 Global 72

Maybridge Chemical Co., Ltd.

Tel: --
Fax: --
Country: Belgium
ProdList: 6293
Advantage: 73

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View Lastest Price from 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine 34950-82-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-08

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34950-82-8