7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Product Name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- CAS No.
- 34950-82-8
- Chemical Name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Synonyms
- 7-bromo-2H,3H,4H-pyrido[3,2-b][1,4]oxazine;7-bromo-3,4-dihydro-2H-pyrido[3,2-β][1,4]oxazine;7-BROMO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE;2H-Pyrido[3,2-b]-1,4-oxazine, 7-bromo-3,4-dihydro-
- CBNumber
- CB8853534
- Molecular Formula
- C7H7BrN2O
- Formula Weight
- 215.05
- MOL File
- 34950-82-8.mol
7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Property
- Melting point:
- 116 °C
- Boiling point:
- 316.8±42.0 °C(Predicted)
- Density
- 1.619±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 7.32±0.20(Predicted)
- form
- solid
- Appearance
- Light yellow to green yellow Solid
Safety
- WGK Germany
- 3
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- ADE001250
- Product name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $817
- Updated
- 2025/07/31
- Product number
- B699683
- Product name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B699683
- Product name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B699683
- Product name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 048483
- Product name
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
- Packaging
- 250mg
- Price
- $342
- Updated
- 2021/12/16
7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Chemical Properties,Usage,Production
Synthesis
20348-23-6
34950-82-8
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine (500 mg, 3.67 mmol) was used as starting material and dissolved in DMF (10 mL). To this solution was added N-bromosuccinimide (NBS, 719 mg, 4.04 mmol) at 0 °C. The reaction mixture was stirred continuously for 2 h at 0 °C. Upon completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 solution and stirring was continued for 20 min at 0 °C. The resulting precipitate was collected by filtration and the solid product was washed with water and dried under vacuum to afford 7-bromo-3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine (549 mg, 2.55 mmol, 69.5% yield) as a brown solid. The product was analyzed by mass spectrometry (ESI+) with a measured value of 215.2 (M + H).1H NMR (300 MHz, CDCl3) δ: 3.50-3.58 (2H, m), 4.18-4.26 (2H, m), 4.82 (1H, brs), 7.10 (1H, d, J = 1.9 Hz), 7.72 (1H, d, J = 2.3 Hz).
References
[1] Patent: WO2018/30550, 2018, A1. Location in patent: Paragraph 0596
[2] Patent: EP2341052, 2011, A1. Location in patent: Page/Page column 40
[3] Acta Chemica Scandinavica (1947-1973), 1971, vol. 25, p. 3135 - 3143
[4] Patent: KR101576386, 2015, B1. Location in patent: Paragraph 0158-0160
7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine Preparation Products And Raw materials
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View Lastest Price from 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine manufacturers
- Product
- 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine 34950-82-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-08