Methyl thiocyanate Property

Melting point:

-5 °C

Boiling point:

131 °C

Density 

1.08

refractive index 

1.467-1.469

Flash point:

38 °C

storage temp. 

Poison room

Water Solubility 

Practically insoluble in water

solubility 

Chloroform (Soluble), Methanol (Slightly)

form 

Liquid

color 

Clear colorless to light yellow

Odor

at 0.01?%?in?propylene glycol. sulfury onion

Sensitive 

Moisture Sensitive

Merck 

14,6127

Dielectric constant

4.3（19℃）

LogP

0.502 (est)

CAS DataBase Reference

556-64-9(CAS DataBase Reference)

NIST Chemistry Reference

Thiocyanic acid, methyl ester(556-64-9)

EPA Substance Registry System

Methyl thiocyanate (556-64-9)

Safety

Hazard Codes 

T

Risk Statements 

23/24/25-10-36/37

Safety Statements 

28A-27-26-16-45-36/37/39

RIDADR 

UN1992

WGK Germany 

3

RTECS 

XL1575000

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29309099

Hazardous Substances Data

556-64-9(Hazardous Substances Data)

Toxicity

LD50 i.p. in mice: 315 nmoles/g (Ohkawa)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Methyl thiocyanate Chemical Properties,Usage,Production

Description

Methyl thiocyanate is a colorless liquid withan onion-like odor. Molecular weight = 73.12; Boilingpoint= 130-133℃; Freezing/Melting point= - 51℃.Very slightly soluble in water.

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Chemical Properties

Methyl thiocyanate is a colorless liquid. Onion-like odor

Uses

Methyl thiocyanate is a reagent that is used in the synthesis of WAK 4103 (W498200), which is a metabolite of Imidacloprid (I274990), a neonicotinoid; the active ingredient in certain neuro-active insecticides. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.Nauen, R., et. al.: Pestic. Sci., 55, 265 (1999); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009); Patial, A., et al.: Env. Ecol., 27, 320 (2009); Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009); Chem. and Eng. News 90: 10 (2012)

Definition

ChEBI: Methyl thiocyanate is a member of the class of thiocyanates, being the methyl ester of thiocyanic acid.

General Description

Colorless liquid and an odor of onions. Used as an agricultural insecticide, a fumigant and as a research chemical. No evidence of commercial production in the U.S.

Air & Water Reactions

Very slightly soluble in water [Merck].

Reactivity Profile

Methyl thiocyanate is a moderately toxic liquid, flammable. Violent, possibly explosive oxidation reaction when mixed with chlorates, nitrates, nitric acid, organic or inorganic peroxides, perchlorates. On contact with mineral acids or acid fumes deadly toxic hydrogen cyanide gas is produced. When heated to decomposition or on contact with mineral acids Methyl thiocyanate emits highly toxic fumes of nitriles, oxides of sulfur and nitrogen [Lewis, 3rd ed., 1993, p. 879, 1234].

Health Hazard

Methyl thiocyanate is highly toxic if ingested. It is a rapidly acting poison.

Fire Hazard

When heated to decomposition, Methyl thiocyanate emits very toxic fumes of oxides of nitrogen and sulfur. (Non-Specific -- Thiocyanates) Incompatible with nitric acid. Violent reactions have occurred when mixed with chlorates, nitrates, nitric acid, organic peroxides, peroxides, potassium chlorate, and sodium chlorate. Methyl thiocyanate is volatile.

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Potential Exposure

It is used as an agricultural insecticide; a fumigant; and as a research chemical. No evidence of commercial production in the United States.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note: Because cyanide is probably largely responsible forpoisonings, antidotal measures against cyanide should beinstituted promptly. Use amyl nitrate capsules if symptomsdevelop. All area employees should be trained regularly inemergency measures for cyanide poisoning and in CPR. Acyanide antidote kit should be kept in the immediate workarea and must be rapidly available. Kit ingredients shouldbe replaced every 1- 2 years to ensure freshness. Personstrained in the use of this kit, oxygen use, and CPR must bequickly available.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers. Where possible, automatically pump liquid from drums or other storage containers to process containers.

Shipping

UN2929 Toxic liquids, flammable, organic, n.o.s., Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Technical Name Required. UN1992 Flammable liquids, toxic, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with nitric acid. Violent reactions have occurred when mixed with chlorates, nitrates, nitric acid; peroxides, potassium chlorate; and sodium chlorate.