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Tetramethylol acetylenediurea

Product Name
Tetramethylol acetylenediurea
CAS No.
5395-50-6
Chemical Name
Tetramethylol acetylenediurea
Synonyms
Tetramethylol acetyl;Tetrahydroxy glycoluril;Tetramethylol glycoluril;Tetramethylol acetylenedurea;Tetramethylol acetylenediurea;Tetramethylol acetylene diuriene;Tetramethylol acetylenediurea TMAD;Tetrakis (hydroxy methy1) glycoluril;1,3,4,6-tetramethylol-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-quinone;Factory supply Tetramethylol Acetylenediurea CAS 5395-50-6 high quality
CBNumber
CB8855149
Molecular Formula
C8H14N4O6
Formula Weight
262.22
MOL File
5395-50-6.mol
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Tetramethylol acetylenediurea Property

Melting point:
137-138 °C
Boiling point:
624.2±55.0 °C(Predicted)
Density 
1.697±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
13.90±0.10(Predicted)
color 
White to Off-White
InChI
InChI=1S/C8H14N4O6/c13-1-9-5-6(11(3-15)7(9)17)12(4-16)8(18)10(5)2-14/h5-6,13-16H,1-4H2
InChIKey
UUGLSEIATNSHRI-UHFFFAOYSA-N
SMILES
C(N1C(N(C2N(C(N(C21)CO)=O)CO)CO)=O)O
EPA Substance Registry System
Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)- (5395-50-6)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3297
Product name
1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
Purity
min. 95.0 %
Packaging
25G
Price
$48
Updated
2025/07/31
TCI Chemical
Product number
T3297
Product name
1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
Purity
min. 95.0 %
Packaging
100G
Price
$118
Updated
2025/07/31
TRC
Product number
T889708
Product name
TetramethylolAcetylenediurea
Packaging
5g
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
098202
Product name
1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo-[4,5-d]imidazole-2,5(1H,3H)-dione
Purity
95+%
Packaging
10g
Price
$19
Updated
2021/12/16
AK Scientific
Product number
J55398
Product name
Tetramethylolacetylenediurea
Packaging
25g
Price
$20
Updated
2021/12/16
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Tetramethylol acetylenediurea Chemical Properties,Usage,Production

Uses

Crosslinker, Fungicide, Concrete additive

Uses

Tetramethylol acetylene diurea is a formaldehyde type of textile-finish resin.

Uses

Tetramethylol Acetylenediurea is a useful additive for forming etching patterns in semiconductor manufacturing.

Flammability and Explosibility

Not classified

Synthesis

50-00-0

496-46-8

5395-50-6

In a suitable reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser, 688 parts (10 mol) of a 44% aqueous formaldehyde solution were added and the pH was adjusted to 8.7 with 22 parts of 0.5 N NaOH solution.The temperature of the reaction system was maintained at 40 °C to which 284 parts (2 mol) of glyburide were subsequently added. During the reaction, the temperature was gradually increased to 55 °C, at which time most of the glyburide was dissolved. After about 15 minutes, the pH of the reaction system was adjusted to 8.0 with 5 parts of 0.5N NaOH solution to obtain a clarified light yellow solution. This solution was subjected to reduced pressure distillation at 50°C to remove the water until about 640 parts remained in the reaction vessel. The concentrated syrupy product was poured into 800 parts of methanol and a white crystalline precipitate was precipitated. After filtration and drying, 483 parts (92% yield) of 1,3,4,6-tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione were obtained with a melting point of 132°C~136°C.

References

[1] Patent: WO2014/166347, 2014, A1. Location in patent: Page/Page column 14
[2] Patent: WO2015/143974, 2015, A1. Location in patent: Page/Page column 15; 16
[3] Chemistry of Heterocyclic Compounds, 2006, vol. 42, # 3, p. 365 - 376
[4] Russian Journal of Applied Chemistry, 2016, vol. 89, # 1, p. 132 - 139
[5] Zh. Prikl. Khim. (S.-Peterburg, Russ. Fed.), 2016, vol. 89, # 1, p. 103 - 111,9

Tetramethylol acetylenediurea Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tetramethylol acetylenediurea manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Tetramethylol acetylenediurea 5395-50-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98
Supply Ability
10000KGS
Release date
2025-11-13
Hebei Chuanghai Biotechnology Co., Ltd
Product
Tetramethylol acetylenediurea 5395-50-6
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Yanxi Chemical Co., Ltd.
Product
Tetramethylol acetylenediurea 5395-50-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-29

5395-50-6, Tetramethylol acetylenediureaRelated Search:

TETRAPHENYLOLETHANE GLYCIDYL ETHER (Hydroxymethyl)urea Urea formaldehyde 2-Hydroxyethyl methacrylate Trimethylolpropane methylol cellulose Imidazole Tetrakis(hydroxymethyl)phosphonium sulfate Tris(hydroxymethyl)aminomethane Glycoluril 1-METHYL-2-IMIDAZOLIDINONE mebikar Dimethylolurea 1,3-Dimethyl-2-imidazolidinone 1,3,4,6-Tetrakis(methoxymethyl)glycoluril DIMETHYLOL ETHYLENE UREA 1,3,4,6-TETRAKIS(BUTOXYMETHYL)GLYCOLURIL, TECH. N-(2-DIMETHYLAMINOETHYL)-N-METHYLFORMAM&

  • Tetramethylol acetylenediurea
  • 1,3,4,6-Tetrakis-hydroxymethyl-tetrahydro-imidazo(4,5-d)imidazole-2,5-dione
  • tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione
  • Tetramethylol acetylenedurea
  • Imidazo4,5-dimidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-
  • Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazol-2,5(1H,3H)-dion
  • Tetramethylol acetylene diuriene
  • Tetrakis (hydroxy methy1) glycoluril
  • 1,3,4,6-Tetrakis(hydroxymethyl)-3a,4,6,6a-tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
  • 1,3,4,6-Tetrakis(hydroxymethyl)octahydroimidazo[4,5-d]imidazole-2,5-dione
  • 3a,4,6,6a-Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione
  • 1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
  • 1,3,4,6-tetramethylol-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-quinone
  • Tetramethylol acetyl
  • 1,3,4,6-Tetrakis(hydroxyMethyl)tetrahydroiMidazo[4,5-d]iMidazole-2,5(1H,3H)-dione
  • 1,3,4,6-Tetrakis-hydroxymethyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dionr in aqueous solution
  • Tetrahydroxy glycoluril
  • Tetramethylol glycoluril
  • Factory supply Tetramethylol Acetylenediurea CAS 5395-50-6 high quality
  • Tetramethylol acetylenediurea TMAD
  • Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione (TMAD)
  • 5395-50-6
  • C8H14N4O6