ChemicalBook > CAS DataBase List > Formyl acetate

Formyl acetate

Product Name
Formyl acetate
CAS No.
2258-42-6
Chemical Name
Formyl acetate
Synonyms
acetic formic anhydride;Acetic acid, anhydride with formic acid;Formic acetic anhydride;FORMYL ACETATE;O-ForMyl Acetate;methanoyl ethanoate;Velpatasvir Impurity 30;Acetic acid formyl ester;2-Thiazolidinethione,4-phenyl-,(5R)-
CBNumber
CB8875125
Molecular Formula
C3H4O3
Formula Weight
88.06
MOL File
2258-42-6.mol
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Formyl acetate Property

Boiling point:
27-28 °C(Press: 1 Torr)
Density 
1.116±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Ethyl Acetate (Soluble), Methanol (Slightly)
form 
Oil
color 
Colourless
Stability:
Air Sensitive, Hygroscopic
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Safety

HS Code 
29159000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0078200
Product name
FORMYL ACETATE
Purity
95.00%
Packaging
500MG
Price
$704.03
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078200
Product name
FORMYL ACETATE
Purity
95.00%
Packaging
1G
Price
$909.56
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078200
Product name
FORMYL ACETATE
Purity
95.00%
Packaging
5G
Price
$1890
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078200
Product name
FORMYL ACETATE
Purity
95.00%
Packaging
10G
Price
$2940
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078200
Product name
FORMYL ACETATE
Purity
95.00%
Packaging
25G
Price
$6825
Updated
2021/12/16
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Formyl acetate Chemical Properties,Usage,Production

Description

Acetic formic anhydride, or ethanoic methanoic anhydride is a chemical compound with formula C3H4O3, or H3C-(C=O)-O-(C=O)H. It can be viewed as the mixed anhydride of acetic acid (H3C- (C=O)OH) and formic acid (H(C= O)OH) by removal of a molecule of water.
It can be produced by reaction between sodium formate and acetyl chloride in anhydrous diethyl ether, at 23–27 °C.Among other uses, it is a formylation agent for amines, amino acids, and alcohols, and a starting material for formyl fluoride.

Chemical Properties

Liquid. Boiling point 27-28°C (1.33kPa). Contact with water accelerates decomposition to produce acetic acid and carbon monoxide.

Uses

Formyl acetate is a useful formylating agent for the hydroxyl, phenol, and amine groups as well as other heteroatoms; useful for the synthesis of aldehydes from aromatic Grignard reagents, for the preparation of formyl  fluoride, and for the preparation of diazoacetaldehyde.

Preparation

Preparative Methods of Formyl acetate: acetic formic anhydride is not comercially available. The easiest method of  preparation is by the reaction of sodium formate and Acetyl Chloride in dry ether as reported by Krimen. Alternatively, Ketene and Formic Acid form the title compound at room temperature or below. Acetic formic anhydride can be prepared rapidly in situ by stirring formic acid, acetyl chloride, and Triethylamine in THF at -70 °C for 10 min. AFA is found in a mixture of formic acid (excess) with Acetic Anhydride. The mixture is more accurately described as formic acid-acetic anhydride mixture (FAM) and is also used  as a formylating agent. Purification: by fractional distillation at low pressure.

storage

Handling, Storage, and Precautions of formyl acetate: it decomposes slowly at room temperature and faster at elevated temperatures, giving acetic acid and carbon monoxide. Due to gas evolution, AFA is best stored at 4 °C in a flask fitted with a polyethylene stopper since sealed samples can explode. The compound is an eye and skin irritant and should be handled in a fume hood.

Formyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Formyl acetate Suppliers

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View Lastest Price from Formyl acetate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Formyl acetate 2258-42-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2025-04-23
Shaanxi Dideu New Materials Co. Ltd
Product
Formyl acetate 2258-42-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-03-31
Shanghai Rlavie Technology Co ltd
Product
Formyl acetate 2258-42-6
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minGC
Supply Ability
50kgs/month
Release date
2021-11-17

2258-42-6, Formyl acetateRelated Search:


  • acetic formic anhydride
  • Acetic acid, anhydride with formic acid
  • Formic acetic anhydride
  • FORMYL ACETATE
  • Acetic acid formyl ester
  • methanoyl ethanoate
  • O-ForMyl Acetate
  • 2-Thiazolidinethione,4-phenyl-,(5R)-
  • Velpatasvir Impurity 30
  • 2258-42-6