methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride
- Product Name
- methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride
- CAS No.
- 1248-42-6
- Chemical Name
- methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride
- Synonyms
- Pitophenone hydrochloride;Baralgin Ketone Hydrochloride;PITOFENONEHYDROCHLORIDE(FORR&DONLY);Pitofenone hydrochloride, 10 mM in DMSO;methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride;methyl 2-[4-(2-piperidin-1-ylethoxy)benzoyl]benzoate hydrochloride;2-[4-(2-piperidinoethoxy)benzoyl]benzoic acid methyl ester hydrochloride;methyl 2-[4-(2-piperidin-1-ylethoxy)phenyl]carbonylbenzoate hydrochloride;Pitofenone hydrochloride,Pitofenone,inhibit,Inhibitor,Cholinesterase (ChE);Benzoic acid,2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-, methyl ester, hydrochloride (1:1)
- CBNumber
- CB8901347
- Molecular Formula
- C22H26ClNO4
- Formula Weight
- 403.89914
- MOL File
- 1248-42-6.mol
methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride Property
- Melting point:
- 169-170°C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- Water Solubility
- H2O: 2mg/mL, clear
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
- Precautionary statements
-
P281Use personal protective equipment as required.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 23865
- Product name
- Pitofenone (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 23865
- Product name
- Pitofenone (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 23865
- Product name
- Pitofenone (hydrochloride)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $286
- Updated
- 2024/03/01
- Product number
- 23865
- Product name
- Pitofenone (hydrochloride)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $535
- Updated
- 2024/03/01
- Product number
- P536500
- Product name
- PitofenoneHydrochloride
- Packaging
- 10mg
- Price
- $145
- Updated
- 2021/12/16
methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride Chemical Properties,Usage,Production
Description
Pitofenone is an antispasmodic agent and an inhibitor of acetylcholinesterase (AChE; Kis = 36 and 45 μM for bovine erythrocyte and electric eel enzyme, respectively). It inhibits acetylcholine-induced contractions of isolated guinea pig ileum when used at a concentration of 2.5 μM.
Chemical Properties
White Solid
Uses
Diclofenac and its combination with Pitofenone and Fenpiverinium shows antispasmodic activity.
IC 50
AChE
References
[1] N S PUNEKAR A V K. Acetylcholinesterase inhibition by pitofenone: a spasmolytic compound.[J]. Biotechnology and applied biochemistry, 1991, 14 3: 378-382.
[2] SHRINIVAS K KULKARNI. Modulatory effect of diclofenac on antispasmodic effect of pitofenone in cholinergic spasm.[J]. Indian journal of experimental biology, 2004, 42 6: 567-569.
methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride manufacturers
- Product
- Pitofenone Hydrochloride 1248-42-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000Kg
- Release date
- 2024-08-08