3-BROMOIMIDAZO[1,2-A]PYRAZINE
- Product Name
- 3-BROMOIMIDAZO[1,2-A]PYRAZINE
- CAS No.
- 57948-41-1
- Chemical Name
- 3-BROMOIMIDAZO[1,2-A]PYRAZINE
- Synonyms
- 3-BROMOIMIDAZO[1,2-A]PYRAZINE;IMidazo[1,2-a]pyrazine, 3-broMo-;3-Bromoimidazo[1,2-a]pyrazine;6-methyl-2-phenyl-4-pyrimidinethiolate;3-BROMOIMIDAZO[1,2-A]PYRAZINE ISO 9001：2015 REACH;3-Bromoimidazo[1,2-a]pyrazine3-Bromoimidazo[1,2-a]pyrazine
- CBNumber
- CB9101685
- Molecular Formula
- C6H4BrN3
- Formula Weight
- 198.02
- MOL File
- 57948-41-1.mol
3-BROMOIMIDAZO[1,2-A]PYRAZINE Property
- Melting point:
- 191-196 °C
- Density
- 1.89±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 1.35±0.30(Predicted)
- form
- powder
- color
- Faint to light beige
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-36/37
- WGK Germany
- 3
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 685798
- Product name
- 3-Bromoimidazo[1,2-a]pyrazine
- Purity
- 96%
- Packaging
- 250mg
- Price
- $139
- Updated
- 2023/06/20
- Product number
- B696293
- Product name
- 3-Bromoimidazo[1,2-a]pyrazine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B696293
- Product name
- 3-Bromoimidazo[1,2-a]pyrazine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR01540
- Product name
- 3-Bromoimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 3H32-9-M8
- Product name
- 3-Bromoimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
3-BROMOIMIDAZO[1,2-A]PYRAZINE Chemical Properties,Usage,Production
Synthesis
274-79-3
57948-41-1
The general procedure for the synthesis of 3-bromoimidazo[1,2-A]pyrazines from indolo[1,2-A]pyrazines was as follows: imidazo[1,2-α]pyrazines (90 mg, 0.76 mmol) and sodium acetate (75 mg, 0.91 mmol) were dissolved in methanol (2 mL) saturated with potassium bromide and the mixture was cooled to -10 °C. Subsequently, bromine (121 mg, 0.76 mmol) was slowly added dropwise over 5 min. After the dropwise addition was completed, 1N sodium sulfite solution (2 mL) was added to terminate the reaction, followed by removal of the solvent under vacuum. The residue was dissolved in a mixture of water (15 mL) and saturated sodium bicarbonate solution (15 mL) and extracted with ethyl acetate (2 x 40 mL). The organic phases were combined, washed with brine (40 mL), dried over anhydrous sodium sulfate and the solvent evaporated to give 3-bromoimidazo[1,2-α]pyrazine (150 mg, 100% yield) as a white crystalline solid. The NMR hydrogen spectrum (400 MHz, CDCl3) data were as follows: δH 7.80 (1H, s), 6.87 (1H, d, J=7 Hz), 7.71 (1H, s), 8.27 (1H, d, J=7 Hz).
References
[1] Patent: US2004/19057, 2004, A1. Location in patent: Page/Page column 9
[2] Tetrahedron, 2011, vol. 67, # 47, p. 9063 - 9066
[3] Patent: WO2010/125101, 2010, A1. Location in patent: Page/Page column 50
[4] Patent: CN104341425, 2018, B. Location in patent: Paragraph 0169; 0171; 0174; 0175
3-BROMOIMIDAZO[1,2-A]PYRAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMOIMIDAZO[1,2-A]PYRAZINE manufacturers
- Product
- 3-bromoimidazo[1,2-a]pyrazine 57948-41-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 800 tons
- Release date
- 2020-04-29
- Product
- 3-BROMOIMIDAZO[1,2-A]PYRAZINE 57948-41-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-10