Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)

Product Name: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
CAS No.: 478149-00-7
Chemical Name: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
Synonyms: thieno[2,3-c]pyridine-2-carboxylic acid;Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
CBNumber: CB91045272
Molecular Formula: C8H5NO2S
Formula Weight: 179.2
MOL File: 478149-00-7.mol

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Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Property

Boiling point:: 418.3±25.0 °C(Predicted)
Density: 1.508±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 2.31±0.30(Predicted)
Appearance: Light brown to brown Solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T344563
Product name: Thieno[2,3-c]pyridine-2-carboxylicAcid
Packaging: 10mg
Price: $40
Updated: 2021/12/16

Matrix Scientific

Product number: 189389
Product name: Thieno[2,3-c]pyridine-2-carboxylic acid
Packaging: 5g
Price: $2206
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: G14637
Product name: Thieno[2,3-c]pyridine-2-carboxylicacid
Packaging: 500mg
Price: $160
Updated: 2021/12/16

Apolloscientific

Product number: OR918586
Product name: Thieno[2,3-c]pyridine-2-carboxylicacid
Purity: 96%
Packaging: 250mg
Price: $210
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: G14637
Product name: Thieno[2,3-c]pyridine-2-carboxylicacid
Packaging: 1g
Price: $240
Updated: 2021/12/16

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Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Chemical Properties,Usage,Production

Uses

Thieno[2,3-c]pyridine-2-carboxylic Acid is used in the preparation of inhibitors such as BET bromodomain inhibitors.

Synthesis

478148-99-1

478149-00-7

Ethyl thieno[2,3-c]pyridine-2-carboxylate (C121, 577 mg, 2.99 mmol) was added to a solvent mixture of methanol (15 mL) and water (1.5 mL) with 2 M sodium hydroxide solution (1.5 mL, 3.0 mmol). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solvent was removed by vacuum concentration and the residue was dissolved in water (75 mL). The solution was acidified to pH 3 with concentrated hydrochloric acid to form a slurry. The solid product was collected by filtration, washed sequentially with water and ether, and dried to give thieno[2,3-c]pyridine-2-carboxylic acid (C122) as an off-white solid in 38% yield. High-resolution mass spectrometry (FAB) analysis showed that the calculated value of C8H5NO2S + H was 180.0119 and the measured value was 180.0119 (M + H)+.

References

[1] Patent: US2003/45540, 2003, A1

Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Suppliers

China 40 Europe 1 India 1 United States 2 Global 44

J & K SCIENTIFIC LTD.

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View Lastest Price from Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) manufacturers

Career Henan Chemical Co

Product: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) 478149-00-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-14

478149-00-7, Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)Related Search:

Thieno[3,2-b]pyridine-5-carboxylic Acid THIENO[2,3-B]PYRIDINE-5-CARBONITRILE Thieno[3,2-b]pyridine-6-carbonitrile (9CI) THIENO[2,3-B]THIOPHENE-2-CARBOXYLIC ACID Thieno[2,3-c]pyridine-7-carboxylic acid (9CI) Thieno[3,2-c]pyridine-2-carboxylic acid thiazolo[4,5-b]pyridine-2(3H)-thione Thieno[2,3-b]pyridin-5-amine (9CI) THIENO[2,3-B]PYRIDINE-2-CARBALDEHYDE PYRIDO[3,2-D][1,3]THIAZOLE-2-THIOL THIENO[3,2-D]PYRIMIDIN-4-AMINE Thieno[2,3-c]pyridin-7-amine (9CI) thiazolo[4,5-b]pyridine-2,6-diaMine Thieno[3,2-b]pyridine-2-c... Thieno[2,3-b]pyrazine Thieno[3,2-b]thiophene-2-carbonitrile THIAZOLO[5,4-B]PYRIDIN-2-AMINE THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID

Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)

thieno[2,3-c]pyridine-2-carboxylic acid

478149-00-7

THIENOPYRIDINE