ChemicalBook > CAS DataBase List > Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)

Product Name
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.
173340-25-5
Chemical Name
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms
Carbamic acid, N-[(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester;cc-000004;R-3-N-Boc-aMinoMethypyrrolidine;(R)-3-N-Boc-aminomethylpyrrolidine;tert-Butyl (3R)-pyrrolidin-3-ylmethylcarbamate;tert-butyl N-[(3R)-pyrrolidin-3-ylmethyl]carbamate;(R)-3-N-Boc-aminomethyl pyrrolidine, CAS 173340-25-5;1,1-Dimethylethyl N-[(3R)-3-pyrrolidinylmethyl]carbamate;(R)-1-pyrrolidin-3-ylmethylcarbamic acid tert-butyl ester;Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
CBNumber
CB91048561
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
173340-25-5.mol
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Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Property

Boiling point:
303.9±15.0 °C(Predicted)
Density 
0.997±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
12.71±0.46(Predicted)
Appearance
white solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
4H51-1-12
Product name
(R)-N-Boc-3-aminomethylpyrrolidine
Purity
95%
Packaging
1g
Price
$125
Updated
2021/12/16
Activate Scientific
Product number
AS36013-A
Product name
(R)-3-N-Boc-(aminomethyl)pyrrolidine
Purity
95+% ee
Packaging
1g
Price
$308
Updated
2021/12/16
Matrix Scientific
Product number
118904
Product name
(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
Purity
95+%
Packaging
1g
Price
$244
Updated
2021/12/16
Activate Scientific
Product number
AS36013-A
Product name
(R)-3-N-Boc-(aminomethyl)pyrrolidine
Purity
95+% ee
Packaging
5G
Price
$935
Updated
2021/12/16
Matrix Scientific
Product number
118904
Product name
(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
Purity
95+%
Packaging
5g
Price
$972
Updated
2021/12/16
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Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production

Uses

(R)-tert-butyl pyrrolidin-3-ylmethylcarbamate is a useful reagent in the research discovery of ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate, a catalytic inhibitor of DNA gyrase and a potential antibacterial agent.

Synthesis

303111-41-3

173340-25-5

General procedure: tert-butyl (R)-(1-benzylpyrrolidin-3-ylmethyl)carbamate (1.00 g, 3.44 mmol) was mixed with 20% Pd/C and subjected to hydrogenation under hydrogen pressure of 50 psi.After 48 h, the reaction mixture was filtered to remove the catalyst, and the filtrate was concentrated to give 511 mg of tert-butyl (3R)-pyrrolidin-3-methylcarbamate ( Yield: 74%). Mass spectrometry analysis (APCI+): m/z 201 ([M + H]+).

References

[1] Patent: WO2005/49602, 2005, A1. Location in patent: Page/Page column 87; 88; 121
[2] Patent: WO2005/49605, 2005, A1. Location in patent: Page/Page column 115; 116; 149

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Career Henan Chemical Co
Product
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) 173340-25-5
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

173340-25-5, Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)Related Search:


  • Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
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