Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
- Product Name
- Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 173340-25-5
- Chemical Name
- Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- Carbamic acid, N-[(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester;cc-000004;R-3-N-Boc-aMinoMethypyrrolidine;(R)-3-N-Boc-aminomethylpyrrolidine;tert-Butyl (3R)-pyrrolidin-3-ylmethylcarbamate;tert-butyl N-[(3R)-pyrrolidin-3-ylmethyl]carbamate;(R)-3-N-Boc-aminomethyl pyrrolidine, CAS 173340-25-5;1,1-Dimethylethyl N-[(3R)-3-pyrrolidinylmethyl]carbamate;(R)-1-pyrrolidin-3-ylmethylcarbamic acid tert-butyl ester;Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
- CBNumber
- CB91048561
- Molecular Formula
- C10H20N2O2
- Formula Weight
- 200.28
- MOL File
- 173340-25-5.mol
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Property
- Boiling point:
- 303.9±15.0 °C(Predicted)
- Density
- 0.997±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 12.71±0.46(Predicted)
- Appearance
- white solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4H51-1-12
- Product name
- (R)-N-Boc-3-aminomethylpyrrolidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- AS36013-A
- Product name
- (R)-3-N-Boc-(aminomethyl)pyrrolidine
- Purity
- 95+% ee
- Packaging
- 1g
- Price
- $308
- Updated
- 2021/12/16
- Product number
- 118904
- Product name
- (R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $244
- Updated
- 2021/12/16
- Product number
- AS36013-A
- Product name
- (R)-3-N-Boc-(aminomethyl)pyrrolidine
- Purity
- 95+% ee
- Packaging
- 5G
- Price
- $935
- Updated
- 2021/12/16
- Product number
- 118904
- Product name
- (R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $972
- Updated
- 2021/12/16
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production
Uses
(R)-tert-butyl pyrrolidin-3-ylmethylcarbamate is a useful reagent in the research discovery of ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate, a catalytic inhibitor of DNA gyrase and a potential antibacterial agent.
Synthesis
303111-41-3
173340-25-5
General procedure: tert-butyl (R)-(1-benzylpyrrolidin-3-ylmethyl)carbamate (1.00 g, 3.44 mmol) was mixed with 20% Pd/C and subjected to hydrogenation under hydrogen pressure of 50 psi.After 48 h, the reaction mixture was filtered to remove the catalyst, and the filtrate was concentrated to give 511 mg of tert-butyl (3R)-pyrrolidin-3-methylcarbamate ( Yield: 74%). Mass spectrometry analysis (APCI+): m/z 201 ([M + H]+).
References
[1] Patent: WO2005/49602, 2005, A1. Location in patent: Page/Page column 87; 88; 121
[2] Patent: WO2005/49605, 2005, A1. Location in patent: Page/Page column 115; 116; 149
Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) manufacturers
- Product
- Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) 173340-25-5
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08