ChemicalBook > CAS DataBase List > Tusamitamab
Tusamitamab
- Product Name
- Tusamitamab
- CAS No.
- 2349294-95-5
- Chemical Name
- Tusamitamab
- Synonyms
- Tusamitamab;Research Grade Tusamitamab;Tusamitamab (anti-CEACAM5);Research Grade Tusamitamab(DHC21006)
- CBNumber
- CB910617060
- Formula Weight
- 0
- MOL File
- Mol file
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Tusamitamab Property
- form
- Liquid
- color
- Colorless to light yellow
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Tusamitamab Chemical Properties,Usage,Production
Uses
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize ADC Tusamitamab ravtansine (SAR408701) (HY-P99542)[1].
Biological Activity
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative).
References
[1] Clemence Pouzin, et al. Covariate analysis of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate, based on first-in-human study. CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11(3):384-394. DOI:10.1002/psp4.12769
Tusamitamab Preparation Products And Raw materials
Raw materials
Preparation Products
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Tusamitamab Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
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