ChemicalBook > CAS DataBase List > Romlusevimab
Romlusevimab
- Product Name
- Romlusevimab
- CAS No.
- 2509447-08-7
- Chemical Name
- Romlusevimab
- Synonyms
- Romlusevimab;Research Grade Romlusevimab;Research Grade Romlusevimab (DVV00312)
- CBNumber
- CB910617121
- Formula Weight
- 0
- MOL File
- Mol file
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Romlusevimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Romlusevimab Chemical Properties,Usage,Production
Uses
Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1][2].
in vivo
Romlusevimab (10 mg/kg, ip, single) in combination with Amubarvimab (HY-P99435) protects animals from Omicron infection in a mouse model of SARS-CoV-2 infection[1].
References
[1] Hoy SM. Amubarvimab/Romlusevimab: First Approval. Drugs. 2022 Aug;82(12):1327-1331. DOI:10.1007/s40265-022-01759-3
[2] Ji Y, et al. Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2. Front Immunol. 2022 Sep 14;13:980435. DOI:10.3389/fimmu.2022.980435
Romlusevimab Preparation Products And Raw materials
Raw materials
Preparation Products
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